46 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PPARA	Peroxisome proliferator activated receptor alpha. (448 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (970 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (784 aa)
	OSBPL8	Oxysterol-binding protein; Belongs to the OSBP family. (889 aa)
	NR1H2	Nuclear receptor subfamily 1 group H member 2. (459 aa)
	VSTM2A	V-set and transmembrane domain containing 2A. (310 aa)
	PPARD	Peroxisome proliferator activated receptor delta. (441 aa)
	APOC4	Uncharacterized protein. (127 aa)
	TTC39B	Tetratricopeptide repeat domain 39B. (682 aa)
	CRP	Pentaxin. (224 aa)
	MSR1	Macrophage scavenger receptor 1. (451 aa)
	SIRT1	Sirtuin 1. (600 aa)
	ACACB	Acetyl-CoA carboxylase beta. (2438 aa)
	NFKBIA	NFKB inhibitor alpha. (317 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type. (403 aa)
	PLIN2	Perilipin; Belongs to the perilipin family. (445 aa)
	OSBPL11	Oxysterol-binding protein; Belongs to the OSBP family. (742 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (453 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2. (230 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
	ITGAV	Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
	ENSCANP00000001668	Uncharacterized protein. (329 aa)
	LOC105507530	Uncharacterized protein. (462 aa)
	VSTM2B	V-set and transmembrane domain containing 2B. (199 aa)
	APOB	Apolipoprotein B. (4555 aa)
	ABHD5	Abhydrolase domain containing 5. (349 aa)
	C3	Complement C3. (1508 aa)
	ABCA1	ATP binding cassette subfamily A member 1. (2264 aa)
	FITM1	Fat storage inducing transmembrane protein 1. (292 aa)
	LPL	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
	SREBF1	Sterol regulatory element binding transcription factor 1. (1148 aa)
	ALKBH7	AlkB homolog 7. (187 aa)
	TTC39A	Tetratricopeptide repeat domain 39A. (612 aa)
	PNPLA2	Patatin like phospholipase domain containing 2. (428 aa)
	ZC3H12A	Zinc finger CCCH-type containing 12A. (601 aa)
	PLIN5	Perilipin; Belongs to the perilipin family. (466 aa)
	CPT1A	Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
	CIDEA	Cell death inducing DFFA like effector a. (219 aa)
	SLC35F5	Solute carrier family 35 member F5. (523 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (472 aa)
	SCARB1	Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
	FBXW7	F-box and WD repeat domain containing 7. (707 aa)
	FITM2	Fat storage inducing transmembrane protein 2. (262 aa)
	IKBKE	Inhibitor of nuclear factor kappa B kinase subunit epsilon. (636 aa)
	SREBF2	Sterol regulatory element binding transcription factor 2. (1123 aa)
	ABCG1	ATP binding cassette subfamily G member 1. (684 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	APOB	ENSCANP00000013051	ENSCANP00000000289	ATP binding cassette subfamily A member 1.	Apolipoprotein B.	0.521
ABCA1	CD36	ENSCANP00000013051	ENSCANP00000033730	ATP binding cassette subfamily A member 1.	CD36 molecule; Belongs to the CD36 family.	0.497
ABCA1	NR1H2	ENSCANP00000013051	ENSCANP00000022606	ATP binding cassette subfamily A member 1.	Nuclear receptor subfamily 1 group H member 2.	0.849
ABCA1	NR1H3	ENSCANP00000013051	ENSCANP00000003636	ATP binding cassette subfamily A member 1.	Nuclear receptor subfamily 1 group H member 3.	0.796
ABCA1	PPARA	ENSCANP00000013051	ENSCANP00000025705	ATP binding cassette subfamily A member 1.	Peroxisome proliferator activated receptor alpha.	0.449
ABCA1	PPARG	ENSCANP00000013051	ENSCANP00000001827	ATP binding cassette subfamily A member 1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.478
ABCA1	SCARB1	ENSCANP00000013051	ENSCANP00000033562	ATP binding cassette subfamily A member 1.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.555
ABCA1	SREBF1	ENSCANP00000013051	ENSCANP00000014093	ATP binding cassette subfamily A member 1.	Sterol regulatory element binding transcription factor 1.	0.540
ABCA1	SREBF2	ENSCANP00000013051	ENSCANP00000027690	ATP binding cassette subfamily A member 1.	Sterol regulatory element binding transcription factor 2.	0.564
ABCG1	NR1H2	ENSCANP00000025257	ENSCANP00000022606	ATP binding cassette subfamily G member 1.	Nuclear receptor subfamily 1 group H member 2.	0.557
ABCG1	NR1H3	ENSCANP00000025257	ENSCANP00000003636	ATP binding cassette subfamily G member 1.	Nuclear receptor subfamily 1 group H member 3.	0.576
ABCG1	PPARG	ENSCANP00000025257	ENSCANP00000001827	ATP binding cassette subfamily G member 1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.430
ABCG1	SCARB1	ENSCANP00000025257	ENSCANP00000033562	ATP binding cassette subfamily G member 1.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.536
ABCG1	SREBF1	ENSCANP00000025257	ENSCANP00000014093	ATP binding cassette subfamily G member 1.	Sterol regulatory element binding transcription factor 1.	0.457
ABCG1	SREBF2	ENSCANP00000025257	ENSCANP00000027690	ATP binding cassette subfamily G member 1.	Sterol regulatory element binding transcription factor 2.	0.519
ABHD5	PLIN2	ENSCANP00000000195	ENSCANP00000005907	Abhydrolase domain containing 5.	Perilipin; Belongs to the perilipin family.	0.741
ABHD5	PLIN5	ENSCANP00000000195	ENSCANP00000037019	Abhydrolase domain containing 5.	Perilipin; Belongs to the perilipin family.	0.647
ABHD5	PNPLA2	ENSCANP00000000195	ENSCANP00000038697	Abhydrolase domain containing 5.	Patatin like phospholipase domain containing 2.	0.943
ACACB	CPT1A	ENSCANP00000007442	ENSCANP00000036344	Acetyl-CoA carboxylase beta.	Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family.	0.908
ACACB	SREBF1	ENSCANP00000007442	ENSCANP00000014093	Acetyl-CoA carboxylase beta.	Sterol regulatory element binding transcription factor 1.	0.580