STRINGSTRING
TREM2 TREM2 ABHD5 ABHD5 OSBPL11 OSBPL11 PLIN2 PLIN2 APOC4 APOC4 FITM1 FITM1 LPL LPL OSBPL8 OSBPL8 PPARA PPARA FITM2 FITM2 CIDEA CIDEA PLIN5 PLIN5 PNPLA2 PNPLA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
ABHD5Abhydrolase domain containing 5. (349 aa)
OSBPL11Oxysterol-binding protein; Belongs to the OSBP family. (742 aa)
PLIN2Perilipin; Belongs to the perilipin family. (445 aa)
APOC4Uncharacterized protein. (127 aa)
FITM1Fat storage inducing transmembrane protein 1. (292 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
OSBPL8Oxysterol-binding protein; Belongs to the OSBP family. (889 aa)
PPARAPeroxisome proliferator activated receptor alpha. (448 aa)
FITM2Fat storage inducing transmembrane protein 2. (262 aa)
CIDEACell death inducing DFFA like effector a. (219 aa)
PLIN5Perilipin; Belongs to the perilipin family. (466 aa)
PNPLA2Patatin like phospholipase domain containing 2. (428 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
Server load: low (16%) [HD]