33 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	OTP	Orthopedia homeobox. (325 aa)
	CDH1	Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (770 aa)
	SALL1	Spalt like transcription factor 1. (1318 aa)
	WNT4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (345 aa)
	PAX6	Paired box 6. (478 aa)
	SIX3	SIX homeobox 3. (363 aa)
	GATA2	GATA binding protein 2. (480 aa)
	PROP1	PROP paired-like homeobox 1. (226 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	HESX1	HESX homeobox 1. (185 aa)
	SLC6A3	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
	ISL1	ISL LIM homeobox 1. (349 aa)
	GHRHR	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (414 aa)
	GLI2	GLI family zinc finger 2. (1585 aa)
	GLI1	GLI family zinc finger 1. (1065 aa)
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
	GHRH	Growth hormone releasing hormone. (107 aa)
	TBX19	T-box transcription factor 19. (448 aa)
	ENSCANP00000003346	Uncharacterized protein. (126 aa)
	ALDH1A2	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (524 aa)
	DUOX2	Dual oxidase 2. (1481 aa)
	LHX3	LIM homeobox 3. (332 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
	GSX1	GS homeobox 1. (264 aa)
	PCSK1	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (749 aa)
	BMP2	Bone morphogenetic protein 2. (396 aa)
	CREB1	cAMP responsive element binding protein 1. (341 aa)
	BMPR1A	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	PITX1	Homeobox protein. (298 aa)
	PITX2	Homeobox protein. (325 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP2	BMP4	ENSCANP00000012981	ENSCANP00000013712	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.871
BMP2	BMPR1A	ENSCANP00000012981	ENSCANP00000013474	Bone morphogenetic protein 2.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.994
BMP2	FGF8	ENSCANP00000012981	ENSCANP00000009026	Bone morphogenetic protein 2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.457
BMP2	NOG	ENSCANP00000012981	ENSCANP00000003971	Bone morphogenetic protein 2.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.992
BMP2	TBX19	ENSCANP00000012981	ENSCANP00000003532	Bone morphogenetic protein 2.	T-box transcription factor 19.	0.497
BMP4	BMP2	ENSCANP00000013712	ENSCANP00000012981	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.871
BMP4	BMPR1A	ENSCANP00000013712	ENSCANP00000013474	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.988
BMP4	FGF10	ENSCANP00000013712	ENSCANP00000008290	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.529
BMP4	FGF8	ENSCANP00000013712	ENSCANP00000009026	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.507
BMP4	NOG	ENSCANP00000013712	ENSCANP00000003971	Bone morphogenetic protein 4.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.978
BMP4	TBX19	ENSCANP00000013712	ENSCANP00000003532	Bone morphogenetic protein 4.	T-box transcription factor 19.	0.497
BMPR1A	BMP2	ENSCANP00000013474	ENSCANP00000012981	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 2.	0.994
BMPR1A	BMP4	ENSCANP00000013474	ENSCANP00000013712	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4.	0.988
BMPR1A	NOG	ENSCANP00000013474	ENSCANP00000003971	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.516
DRD2	SLC6A3	ENSCANP00000040001	ENSCANP00000035491	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.940
FGF10	BMP4	ENSCANP00000008290	ENSCANP00000013712	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 4.	0.529
FGF10	FGF8	ENSCANP00000008290	ENSCANP00000009026	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.570
FGF10	NOG	ENSCANP00000008290	ENSCANP00000003971	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.400
FGF8	BMP2	ENSCANP00000009026	ENSCANP00000012981	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 2.	0.457
FGF8	BMP4	ENSCANP00000009026	ENSCANP00000013712	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 4.	0.507