58 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LDLRAP1	Low density lipoprotein receptor adaptor protein 1. (278 aa)
	SYT7	Synaptotagmin 7. (600 aa)
	CLU	Clusterin. (534 aa)
	ABCG4	ATP binding cassette subfamily G member 4. (646 aa)
	STARD4	StAR related lipid transfer domain containing 4. (205 aa)
	STAR	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
	STARD3NL	MENTAL domain-containing protein. (234 aa)
	NPC1	NPC intracellular cholesterol transporter 1. (1277 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (472 aa)
	SCARB1	Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
	ARL8A	ADP ribosylation factor like GTPase 8A; Belongs to the small GTPase superfamily. Arf family. (174 aa)
	ARV1	ARV1 homolog, fatty acid homeostasis modulator. (271 aa)
	ABCA8	ATP binding cassette subfamily A member 8. (1621 aa)
	LRP6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
	NPC1L1	NPC1 like intracellular cholesterol transporter 1. (1326 aa)
	SOAT1	O-acyltransferase. (525 aa)
	ENSCANP00000029321	Uncharacterized protein. (168 aa)
	STARD5	StAR related lipid transfer domain containing 5. (213 aa)
	PIP4K2A	Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (358 aa)
	ABCA12	ATP binding cassette subfamily A member 12. (2556 aa)
	ABCG1	ATP binding cassette subfamily G member 1. (684 aa)
	ABCG5	ATP binding cassette subfamily G member 5. (651 aa)
	LIMA1	LIM domain and actin binding 1. (753 aa)
	HNF1A	HNF1 homeobox A. (662 aa)
	ABCG8	ATP binding cassette subfamily G member 8. (620 aa)
	LIPG	Lipase G, endothelial type. (500 aa)
	NPC2	NPC intracellular cholesterol transporter 2. (229 aa)
	TPCN2	Two pore segment channel 2. (728 aa)
	CFTR	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1481 aa)
	APOE	Apolipoprotein E. (189 aa)
	ABCA7	ATP binding cassette subfamily A member 7. (2000 aa)
	ABCA5	ATP binding cassette subfamily A member 5. (1642 aa)
	ARL8B	ADP ribosylation factor like GTPase 8B; Belongs to the small GTPase superfamily. Arf family. (186 aa)
	ENSCANP00000017804	Uncharacterized protein. (333 aa)
	RELCH	RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1250 aa)
	CETP	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (493 aa)
	OSBPL2	Oxysterol-binding protein; Belongs to the OSBP family. (470 aa)
	LCAT	Lecithin-cholesterol acyltransferase. (440 aa)
	STARD3	StAR related lipid transfer domain containing 3. (484 aa)
	STX12	Syntaxin 12; Belongs to the syntaxin family. (276 aa)
	ABCA1	ATP binding cassette subfamily A member 1. (2264 aa)
	SOAT2	O-acyltransferase. (460 aa)
	CEL	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (650 aa)
	APOA2	Apolipoprotein A2. (100 aa)
	LIPC	Lipase C, hepatic type. (499 aa)
	SPG11	SPG11 vesicle trafficking associated, spatacsin. (2442 aa)
	LDLR	Low density lipoprotein receptor. (777 aa)
	OSBP	Oxysterol-binding protein; Belongs to the OSBP family. (726 aa)
	MSR1	Macrophage scavenger receptor 1. (451 aa)
	APOA5	Apolipoprotein A5. (366 aa)
	TSPO2	Translocator protein 2. (170 aa)
	SCP2	Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)
	ENSCANP00000005043	MENTAL domain-containing protein. (207 aa)
	TSKU	Tsukushi, small leucine rich proteoglycan. (353 aa)
	VPS4A	Uncharacterized protein; Belongs to the AAA ATPase family. (450 aa)
	APOB	Apolipoprotein B. (4555 aa)
	SERAC1	Serine active site containing 1. (654 aa)
	APOC2	Apolipoprotein C2. (101 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	APOA2	ENSCANP00000013051	ENSCANP00000010601	ATP binding cassette subfamily A member 1.	Apolipoprotein A2.	0.530
ABCA1	APOB	ENSCANP00000013051	ENSCANP00000000289	ATP binding cassette subfamily A member 1.	Apolipoprotein B.	0.521
ABCA1	APOE	ENSCANP00000013051	ENSCANP00000019437	ATP binding cassette subfamily A member 1.	Apolipoprotein E.	0.734
ABCA1	CD36	ENSCANP00000013051	ENSCANP00000033730	ATP binding cassette subfamily A member 1.	CD36 molecule; Belongs to the CD36 family.	0.497
ABCA1	CETP	ENSCANP00000013051	ENSCANP00000016325	ATP binding cassette subfamily A member 1.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.720
ABCA1	LCAT	ENSCANP00000013051	ENSCANP00000015211	ATP binding cassette subfamily A member 1.	Lecithin-cholesterol acyltransferase.	0.546
ABCA1	NPC1	ENSCANP00000013051	ENSCANP00000035788	ATP binding cassette subfamily A member 1.	NPC intracellular cholesterol transporter 1.	0.417
ABCA1	NPC1L1	ENSCANP00000013051	ENSCANP00000030392	ATP binding cassette subfamily A member 1.	NPC1 like intracellular cholesterol transporter 1.	0.423
ABCA1	SCARB1	ENSCANP00000013051	ENSCANP00000033562	ATP binding cassette subfamily A member 1.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.555
ABCA7	CLU	ENSCANP00000019283	ENSCANP00000039028	ATP binding cassette subfamily A member 7.	Clusterin.	0.416
ABCG1	ABCG5	ENSCANP00000025257	ENSCANP00000024966	ATP binding cassette subfamily G member 1.	ATP binding cassette subfamily G member 5.	0.878
ABCG1	APOE	ENSCANP00000025257	ENSCANP00000019437	ATP binding cassette subfamily G member 1.	Apolipoprotein E.	0.557
ABCG1	NPC1	ENSCANP00000025257	ENSCANP00000035788	ATP binding cassette subfamily G member 1.	NPC intracellular cholesterol transporter 1.	0.424
ABCG1	SCARB1	ENSCANP00000025257	ENSCANP00000033562	ATP binding cassette subfamily G member 1.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.536
ABCG4	ABCG5	ENSCANP00000038546	ENSCANP00000024966	ATP binding cassette subfamily G member 4.	ATP binding cassette subfamily G member 5.	0.878
ABCG5	ABCG1	ENSCANP00000024966	ENSCANP00000025257	ATP binding cassette subfamily G member 5.	ATP binding cassette subfamily G member 1.	0.878
ABCG5	ABCG4	ENSCANP00000024966	ENSCANP00000038546	ATP binding cassette subfamily G member 5.	ATP binding cassette subfamily G member 4.	0.878
ABCG5	ABCG8	ENSCANP00000024966	ENSCANP00000022993	ATP binding cassette subfamily G member 5.	ATP binding cassette subfamily G member 8.	0.999
ABCG5	APOB	ENSCANP00000024966	ENSCANP00000000289	ATP binding cassette subfamily G member 5.	Apolipoprotein B.	0.439
ABCG5	APOE	ENSCANP00000024966	ENSCANP00000019437	ATP binding cassette subfamily G member 5.	Apolipoprotein E.	0.494