STRINGSTRING
TWSG1 TWSG1 BMP4 BMP4 ZNF423 ZNF423 GDF2 GDF2 NUMA1 NUMA1 CDH5 CDH5 FKBP8 FKBP8 GDF5 GDF5 SULF1 SULF1 NOTCH1 NOTCH1 SMAD4 SMAD4 SCUBE3 SCUBE3 BMPR2 BMPR2 MSX1 MSX1 KDR KDR TBX20 TBX20 NEO1 NEO1 ENSCANP00000036443 ENSCANP00000036443 SMAD2 SMAD2 GATA4 GATA4 ENG ENG CCN1 CCN1 GATA6 GATA6 KCP KCP PELO PELO RNF165 RNF165 NOTCH2 NOTCH2 CRB2 CRB2 SOX11 SOX11 UBE2O UBE2O FBXL15 FBXL15 ACVRL1 ACVRL1 KIAA1324L KIAA1324L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
ZNF423Zinc finger protein 423. (1191 aa)
GDF2Growth differentiation factor 2. (429 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2118 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (717 aa)
FKBP8Peptidylprolyl isomerase. (421 aa)
GDF5Growth differentiation factor 5. (499 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (873 aa)
NOTCH1Notch receptor 1. (2559 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
SCUBE3Signal peptide, CUB domain and EGF like domain containing 3. (993 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1030 aa)
MSX1Msh homeobox 1. (199 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
TBX20T-box transcription factor 20. (447 aa)
NEO1Neogenin 1. (1451 aa)
ENSCANP00000036443TPR_REGION domain-containing protein. (356 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
GATA4GATA binding protein 4. (236 aa)
ENGEndoglin. (658 aa)
CCN1Cellular communication network factor 1. (381 aa)
GATA6GATA binding protein 6. (462 aa)
KCPKielin cysteine rich BMP regulator. (1575 aa)
PELOProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
RNF165Ring finger protein 165. (346 aa)
NOTCH2Notch receptor 2. (2471 aa)
CRB2Crumbs cell polarity complex component 2. (1287 aa)
SOX11Transcription factor SOX. (372 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1154 aa)
FBXL15F-box and leucine rich repeat protein 15. (300 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
KIAA1324LKIAA1324 like. (1019 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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