19 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	USP25	Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family. (1110 aa)
	PML	Promyelocytic leukemia. (882 aa)
	SERBP1	SERPINE1 mRNA binding protein 1. (408 aa)
	ENSCANP00000012396	HECT domain-containing protein. (423 aa)
	USPL1	Ubiquitin specific peptidase like 1. (1093 aa)
	RNF4	Ring finger protein 4. (190 aa)
	UBA2	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (571 aa)
	CBX7	Chromobox 7. (251 aa)
	ENSCANP00000019016	Uncharacterized protein. (149 aa)
	TOLLIP	Toll interacting protein. (272 aa)
	GCNA	Germ cell nuclear acidic peptidase. (577 aa)
	HABP4	Hyaluronan binding protein 4. (371 aa)
	TDG	Thymine DNA glycosylase. (410 aa)
	SIMC1	SUMO interacting motifs containing 1. (844 aa)
	ENSCANP00000034099	Uncharacterized protein. (306 aa)
	HERC2	HECT and RLD domain containing E3 ubiquitin protein ligase 2. (4683 aa)
	CASP8AP2	Caspase 8 associated protein 2. (1985 aa)
	CBX4	Chromobox 4. (613 aa)
	RNF111	Ring finger protein 111. (994 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP8AP2	CBX4	ENSCANP00000037879	ENSCANP00000039724	Caspase 8 associated protein 2.	Chromobox 4.	0.418
CBX4	CASP8AP2	ENSCANP00000039724	ENSCANP00000037879	Chromobox 4.	Caspase 8 associated protein 2.	0.418
CBX4	CBX7	ENSCANP00000039724	ENSCANP00000018443	Chromobox 4.	Chromobox 7.	0.731
CBX7	CBX4	ENSCANP00000018443	ENSCANP00000039724	Chromobox 7.	Chromobox 4.	0.731
PML	RNF4	ENSCANP00000007358	ENSCANP00000014176	Promyelocytic leukemia.	Ring finger protein 4.	0.838
RNF111	RNF4	ENSCANP00000040349	ENSCANP00000014176	Ring finger protein 111.	Ring finger protein 4.	0.431
RNF4	PML	ENSCANP00000014176	ENSCANP00000007358	Ring finger protein 4.	Promyelocytic leukemia.	0.838
RNF4	RNF111	ENSCANP00000014176	ENSCANP00000040349	Ring finger protein 4.	Ring finger protein 111.	0.431