26 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

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protein homology

Your Input:
	LOC105515301	Uncharacterized protein. (369 aa)
	DERL2	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
	DERL1	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa)
	RANGRF	RAN guanine nucleotide release factor. (186 aa)
	RHBDD1	Rhomboid domain containing 1. (316 aa)
	HM13	Histocompatibility minor 13. (425 aa)
	SEL1L	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (794 aa)
	SEC16A	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2296 aa)
	SLC35D3	Solute carrier family 35 member D3. (416 aa)
	NPLOC4	NPL4 homolog, ubiquitin recognition factor. (560 aa)
	MAP1LC3C	Microtubule associated protein 1 light chain 3 gamma. (177 aa)
	PREB	WD_REPEATS_REGION domain-containing protein. (417 aa)
	AUP1	AUP1 lipid droplet regulating VLDL assembly factor. (410 aa)
	VCP	Valosin containing protein; Belongs to the AAA ATPase family. (804 aa)
	SYVN1	Synoviolin 1. (616 aa)
	FAF2	Fas associated factor family member 2. (445 aa)
	HSP90B1	Heat shock protein 90 beta family member 1. (804 aa)
	LOC105509796	Uncharacterized protein. (294 aa)
	LOC105522998	Uncharacterized protein. (693 aa)
	SEC13	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (368 aa)
	SEC61B	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
	OS9	OS9 endoplasmic reticulum lectin. (731 aa)
	TMEM129	Transmembrane protein 129. (362 aa)
	TECPR2	Tectonin beta-propeller repeat containing 2. (1365 aa)
	SELENOS	Selenoprotein S. (188 aa)
	UFD1	Ubiquitin recognition factor in ER associated degradation 1. (307 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AUP1	DERL2	ENSCANP00000013427	ENSCANP00000023356	AUP1 lipid droplet regulating VLDL assembly factor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.661
AUP1	FAF2	ENSCANP00000013427	ENSCANP00000037175	AUP1 lipid droplet regulating VLDL assembly factor.	Fas associated factor family member 2.	0.682
AUP1	OS9	ENSCANP00000013427	ENSCANP00000014179	AUP1 lipid droplet regulating VLDL assembly factor.	OS9 endoplasmic reticulum lectin.	0.577
AUP1	SEL1L	ENSCANP00000013427	ENSCANP00000008574	AUP1 lipid droplet regulating VLDL assembly factor.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.859
AUP1	SYVN1	ENSCANP00000013427	ENSCANP00000039271	AUP1 lipid droplet regulating VLDL assembly factor.	Synoviolin 1.	0.818
AUP1	VCP	ENSCANP00000013427	ENSCANP00000039737	AUP1 lipid droplet regulating VLDL assembly factor.	Valosin containing protein; Belongs to the AAA ATPase family.	0.639
DERL1	DERL2	ENSCANP00000019535	ENSCANP00000023356	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.969
DERL1	FAF2	ENSCANP00000019535	ENSCANP00000037175	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Fas associated factor family member 2.	0.760
DERL1	HM13	ENSCANP00000019535	ENSCANP00000006666	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Histocompatibility minor 13.	0.802
DERL1	HSP90B1	ENSCANP00000019535	ENSCANP00000034613	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Heat shock protein 90 beta family member 1.	0.438
DERL1	LOC105509796	ENSCANP00000019535	ENSCANP00000031694	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Uncharacterized protein.	0.938
DERL1	LOC105522998	ENSCANP00000019535	ENSCANP00000031127	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Uncharacterized protein.	0.438
DERL1	NPLOC4	ENSCANP00000019535	ENSCANP00000011425	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	NPL4 homolog, ubiquitin recognition factor.	0.928
DERL1	OS9	ENSCANP00000019535	ENSCANP00000014179	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	OS9 endoplasmic reticulum lectin.	0.973
DERL1	SEC61B	ENSCANP00000019535	ENSCANP00000025553	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.413
DERL1	SEL1L	ENSCANP00000019535	ENSCANP00000008574	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.983
DERL1	SELENOS	ENSCANP00000019535	ENSCANP00000014937	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Selenoprotein S.	0.917
DERL1	SYVN1	ENSCANP00000019535	ENSCANP00000039271	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Synoviolin 1.	0.989
DERL1	TMEM129	ENSCANP00000019535	ENSCANP00000014491	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Transmembrane protein 129.	0.711
DERL1	UFD1	ENSCANP00000019535	ENSCANP00000016704	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ubiquitin recognition factor in ER associated degradation 1.	0.938