33 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FOSL1	FOS like 1, AP-1 transcription factor subunit. (271 aa)
	SRC	Tyrosine-protein kinase. (458 aa)
	CYP1B1	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
	TACR1	Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
	TYMS	Thymidylate synthetase. (313 aa)
	FOSB	FosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	NCOA2	Nuclear receptor coactivator. (1468 aa)
	WBP2	WW domain binding protein 2. (261 aa)
	SOX10	SRY-box transcription factor 10. (466 aa)
	NKX2-2	NK2 homeobox 2. (273 aa)
	THBS1	Thrombospondin 1. (1173 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	FOS	Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
	ACOD1	Aconitate decarboxylase 1. (481 aa)
	YAP1	Yes associated protein 1. (479 aa)
	ABHD2	Abhydrolase domain containing 2. (444 aa)
	SREBF1	Sterol regulatory element binding transcription factor 1. (1148 aa)
	ENSCANP00000013869	Thymidylat_synt domain-containing protein. (134 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1335 aa)
	TSPO	Uncharacterized protein. (65 aa)
	ENSCANP00000010884	Uncharacterized protein. (338 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (179 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (336 aa)
	CSN1S1	Casein alpha s1. (184 aa)
	PTGER2	Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (358 aa)
	BAD	BCL2 associated agonist of cell death. (167 aa)
	CLDN4	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (453 aa)
	UBE3A	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (875 aa)
	TRERF1	Transcriptional regulating factor 1. (1216 aa)
	DSG1	Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1038 aa)
	GABRB1	Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAV1	IGF1R	ENSCANP00000008835	ENSCANP00000013040	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Tyrosine-protein kinase receptor.	0.590
CAV1	SRC	ENSCANP00000008835	ENSCANP00000040204	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Tyrosine-protein kinase.	0.912
ENSCANP00000010884	SRC	ENSCANP00000010884	ENSCANP00000040204	Uncharacterized protein.	Tyrosine-protein kinase.	0.536
ENSCANP00000010884	WBP2	ENSCANP00000010884	ENSCANP00000027342	Uncharacterized protein.	WW domain binding protein 2.	0.701
FOS	FOSB	ENSCANP00000019070	ENSCANP00000035705	Fos proto-oncogene, AP-1 transcription factor subunit.	FosB proto-oncogene, AP-1 transcription factor subunit.	0.990
FOS	FOSL1	ENSCANP00000019070	ENSCANP00000033933	Fos proto-oncogene, AP-1 transcription factor subunit.	FOS like 1, AP-1 transcription factor subunit.	0.935
FOS	NCOA2	ENSCANP00000019070	ENSCANP00000029864	Fos proto-oncogene, AP-1 transcription factor subunit.	Nuclear receptor coactivator.	0.608
FOS	SRC	ENSCANP00000019070	ENSCANP00000040204	Fos proto-oncogene, AP-1 transcription factor subunit.	Tyrosine-protein kinase.	0.913
FOS	THBS1	ENSCANP00000019070	ENSCANP00000021550	Fos proto-oncogene, AP-1 transcription factor subunit.	Thrombospondin 1.	0.461
FOSB	FOS	ENSCANP00000035705	ENSCANP00000019070	FosB proto-oncogene, AP-1 transcription factor subunit.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.990
FOSB	FOSL1	ENSCANP00000035705	ENSCANP00000033933	FosB proto-oncogene, AP-1 transcription factor subunit.	FOS like 1, AP-1 transcription factor subunit.	0.935
FOSL1	FOS	ENSCANP00000033933	ENSCANP00000019070	FOS like 1, AP-1 transcription factor subunit.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.935
FOSL1	FOSB	ENSCANP00000033933	ENSCANP00000035705	FOS like 1, AP-1 transcription factor subunit.	FosB proto-oncogene, AP-1 transcription factor subunit.	0.935
IGF1R	CAV1	ENSCANP00000013040	ENSCANP00000008835	Tyrosine-protein kinase receptor.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.590
IGF1R	SRC	ENSCANP00000013040	ENSCANP00000040204	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase.	0.926
NCOA2	FOS	ENSCANP00000029864	ENSCANP00000019070	Nuclear receptor coactivator.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.608
NCOA2	NR1H3	ENSCANP00000029864	ENSCANP00000003636	Nuclear receptor coactivator.	Nuclear receptor subfamily 1 group H member 3.	0.943
NCOA2	SRC	ENSCANP00000029864	ENSCANP00000040204	Nuclear receptor coactivator.	Tyrosine-protein kinase.	0.440
NR1H3	NCOA2	ENSCANP00000003636	ENSCANP00000029864	Nuclear receptor subfamily 1 group H member 3.	Nuclear receptor coactivator.	0.943
NR1H3	SREBF1	ENSCANP00000003636	ENSCANP00000014093	Nuclear receptor subfamily 1 group H member 3.	Sterol regulatory element binding transcription factor 1.	0.600