STRINGSTRING
DACT2 DACT2 LOC105517683 LOC105517683 ACVR1 ACVR1 FGF10 FGF10 FSTL3 FSTL3 MEN1 MEN1 IGSF1 IGSF1 DAND5 DAND5 ACVR2A ACVR2A ZC3H3 ZC3H3 FGF9 FGF9 ACVR1B ACVR1B CER1 CER1 ACVR2B ACVR2B SHH SHH SKI SKI MAGI2 MAGI2 LEMD3 LEMD3 NODAL NODAL DMRT1 DMRT1 SMAD2 SMAD2 SMAD7 SMAD7 FST FST
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DACT2Dishevelled binding antagonist of beta catenin 2. (737 aa)
LOC105517683Uncharacterized protein. (1202 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FSTL3Kazal-like domain-containing protein. (70 aa)
MEN1Menin 1. (610 aa)
IGSF1Immunoglobulin superfamily member 1. (1341 aa)
DAND5DAN domain BMP antagonist family member 5. (189 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
ZC3H3Zinc finger CCCH-type containing 3. (948 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (750 aa)
SHHSonic hedgehog signaling molecule. (390 aa)
SKISKI proto-oncogene. (649 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1259 aa)
LEMD3LEM domain containing 3. (903 aa)
NODALNodal growth differentiation factor. (347 aa)
DMRT1Doublesex and mab-3 related transcription factor 1. (373 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
SMAD7Mothers against decapentaplegic homolog. (431 aa)
FSTFollistatin. (317 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.