14 items (Colobus angolensis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LRP8	LDL receptor related protein 8. (880 aa)
	MTTP	Microsomal triglyceride transfer protein. (909 aa)
	LPL	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
	ABCA1	ATP binding cassette subfamily A member 1. (2264 aa)
	LIPC	Lipase C, hepatic type. (499 aa)
	LILRB4	Leukocyte immunoglobulin like receptor B4. (448 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2. (230 aa)
	VLDLR	Very low density lipoprotein receptor. (873 aa)
	LRP1	LDL receptor related protein 1. (4544 aa)
	PCSK9	Proprotein convertase subtilisin/kexin type 9. (692 aa)
	ENSCANP00000034239	Uncharacterized protein. (1410 aa)
	SCARB1	Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
	LRP4	LDL receptor related protein 4. (1898 aa)
	LCAT	Lecithin-cholesterol acyltransferase. (440 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	LCAT	ENSCANP00000013051	ENSCANP00000015211	ATP binding cassette subfamily A member 1.	Lecithin-cholesterol acyltransferase.	0.546
ABCA1	SCARB1	ENSCANP00000013051	ENSCANP00000033562	ATP binding cassette subfamily A member 1.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.555
ENSCANP00000034239	LIPC	ENSCANP00000034239	ENSCANP00000010110	Uncharacterized protein.	Lipase C, hepatic type.	0.690
ENSCANP00000034239	MTTP	ENSCANP00000034239	ENSCANP00000014396	Uncharacterized protein.	Microsomal triglyceride transfer protein.	0.420
LCAT	ABCA1	ENSCANP00000015211	ENSCANP00000013051	Lecithin-cholesterol acyltransferase.	ATP binding cassette subfamily A member 1.	0.546
LCAT	LIPC	ENSCANP00000015211	ENSCANP00000010110	Lecithin-cholesterol acyltransferase.	Lipase C, hepatic type.	0.612
LCAT	LPL	ENSCANP00000015211	ENSCANP00000013730	Lecithin-cholesterol acyltransferase.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.598
LCAT	SCARB1	ENSCANP00000015211	ENSCANP00000033562	Lecithin-cholesterol acyltransferase.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.410
LIPC	ENSCANP00000034239	ENSCANP00000010110	ENSCANP00000034239	Lipase C, hepatic type.	Uncharacterized protein.	0.690
LIPC	LCAT	ENSCANP00000010110	ENSCANP00000015211	Lipase C, hepatic type.	Lecithin-cholesterol acyltransferase.	0.612
LIPC	LPL	ENSCANP00000010110	ENSCANP00000013730	Lipase C, hepatic type.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.930
LIPC	LRP8	ENSCANP00000010110	ENSCANP00000006932	Lipase C, hepatic type.	LDL receptor related protein 8.	0.447
LIPC	VLDLR	ENSCANP00000010110	ENSCANP00000002238	Lipase C, hepatic type.	Very low density lipoprotein receptor.	0.786
LPL	LCAT	ENSCANP00000013730	ENSCANP00000015211	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	Lecithin-cholesterol acyltransferase.	0.598
LPL	LIPC	ENSCANP00000013730	ENSCANP00000010110	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	Lipase C, hepatic type.	0.930
LPL	LRP1	ENSCANP00000013730	ENSCANP00000039812	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	LDL receptor related protein 1.	0.900
LPL	LRP4	ENSCANP00000013730	ENSCANP00000032573	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	LDL receptor related protein 4.	0.514
LPL	LRP8	ENSCANP00000013730	ENSCANP00000006932	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	LDL receptor related protein 8.	0.430
LPL	SCARB1	ENSCANP00000013730	ENSCANP00000033562	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.472
LPL	VLDLR	ENSCANP00000013730	ENSCANP00000002238	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	Very low density lipoprotein receptor.	0.803