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APOB APOB PLTP PLTP SCARB1 SCARB1 PLA2G2A PLA2G2A ABCG1 ABCG1 APOA5 APOA5 LIPC LIPC APOA2 APOA2 LPL LPL MTTP MTTP MPO MPO PLA2G5 PLA2G5 LIPG LIPG PLA2G2E PLA2G2E APOE APOE ABCA5 ABCA5 CETP CETP LCAT LCAT PLA2G7 PLA2G7 PLA2G3 PLA2G3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APOBApolipoprotein B. (4555 aa)
PLTPPhospholipid transfer protein. (493 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
PLA2G2APhospholipase A(2). (144 aa)
ABCG1ATP binding cassette subfamily G member 1. (684 aa)
APOA5Apolipoprotein A5. (366 aa)
LIPCLipase C, hepatic type. (499 aa)
APOA2Apolipoprotein A2. (100 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
MTTPMicrosomal triglyceride transfer protein. (909 aa)
MPOMyeloperoxidase. (745 aa)
PLA2G5Phospholipase A(2). (138 aa)
LIPGLipase G, endothelial type. (500 aa)
PLA2G2EPhospholipase A(2). (142 aa)
APOEApolipoprotein E. (189 aa)
ABCA5ATP binding cassette subfamily A member 5. (1642 aa)
CETPCholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (493 aa)
LCATLecithin-cholesterol acyltransferase. (440 aa)
PLA2G7Platelet-activating factor acetylhydrolase. (440 aa)
PLA2G3Phospholipase A2 group III. (509 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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