(13 nodes) Maintenance of protein localization in endoplasmic reticulum network (Colobus angolensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	OS9	OS9 endoplasmic reticulum lectin. (731 aa)
	LOC105521187	Uncharacterized protein; Belongs to the heat shock protein 70 family. (546 aa)
	PDIA2	Protein disulfide isomerase family A member 2. (525 aa)
	GPAA1	Glycosylphosphatidylinositol anchor attachment 1. (621 aa)
	KDELR2	Uncharacterized protein. (155 aa)
	INSIG2	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
	ANKRD13C	Ankyrin repeat domain 13C. (541 aa)
	HSPA5	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
	GRIK5	Glutamate ionotropic receptor kainate type subunit 5. (952 aa)
	KDELR3	ER lumen protein-retaining receptor. (214 aa)
	TAPT1	Transmembrane anterior posterior transformation 1. (500 aa)
	INSIG1	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa)
	KDELR1	KDEL endoplasmic reticulum protein retention receptor 1. (220 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HSPA5	OS9	ENSCANP00000035472	ENSCANP00000014179	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	OS9 endoplasmic reticulum lectin.	0.655
HSPA5	PDIA2	ENSCANP00000035472	ENSCANP00000016809	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	Protein disulfide isomerase family A member 2.	0.909
LOC105521187	OS9	ENSCANP00000014811	ENSCANP00000014179	Uncharacterized protein; Belongs to the heat shock protein 70 family.	OS9 endoplasmic reticulum lectin.	0.655
LOC105521187	PDIA2	ENSCANP00000014811	ENSCANP00000016809	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Protein disulfide isomerase family A member 2.	0.909
OS9	HSPA5	ENSCANP00000014179	ENSCANP00000035472	OS9 endoplasmic reticulum lectin.	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	0.655
OS9	LOC105521187	ENSCANP00000014179	ENSCANP00000014811	OS9 endoplasmic reticulum lectin.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.655
OS9	PDIA2	ENSCANP00000014179	ENSCANP00000016809	OS9 endoplasmic reticulum lectin.	Protein disulfide isomerase family A member 2.	0.518
PDIA2	HSPA5	ENSCANP00000016809	ENSCANP00000035472	Protein disulfide isomerase family A member 2.	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	0.909
PDIA2	LOC105521187	ENSCANP00000016809	ENSCANP00000014811	Protein disulfide isomerase family A member 2.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.909
PDIA2	OS9	ENSCANP00000016809	ENSCANP00000014179	Protein disulfide isomerase family A member 2.	OS9 endoplasmic reticulum lectin.	0.518