STRINGSTRING
RAD51 RAD51 RING1 RING1 BRCA2 BRCA2 CUL4B CUL4B PCGF6 PCGF6 ENSCANP00000013426 ENSCANP00000013426 KDM2B KDM2B TRIM37 TRIM37 PCGF5 PCGF5 BCOR BCOR ENSCANP00000018891 ENSCANP00000018891 DDB1 DDB1 PCGF1 PCGF1 RNF168 RNF168 ENSCANP00000025746 ENSCANP00000025746 BARD1 BARD1 SKP1 SKP1 RNF2 RNF2 LOC105527518 LOC105527518 RYBP RYBP PCGF2 PCGF2 DDB2 DDB2 ENSCANP00000033944 ENSCANP00000033944 PCGF3 PCGF3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (299 aa)
RING1Ring finger protein 1. (406 aa)
BRCA2BRCA2 DNA repair associated. (3412 aa)
CUL4BCullin 4B; Belongs to the cullin family. (870 aa)
PCGF6Polycomb group ring finger 6. (288 aa)
ENSCANP00000013426RING-type domain-containing protein. (324 aa)
KDM2BLysine demethylase 2B. (1336 aa)
TRIM37Tripartite motif containing 37. (956 aa)
PCGF5Polycomb group ring finger 5. (256 aa)
BCORBCL6 corepressor. (1755 aa)
ENSCANP00000018891Uncharacterized protein; Belongs to the SKP1 family. (137 aa)
DDB1Damage specific DNA binding protein 1. (1147 aa)
PCGF1Polycomb group ring finger 1. (259 aa)
RNF168E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (571 aa)
ENSCANP00000025746Uncharacterized protein; Belongs to the SKP1 family. (167 aa)
BARD1BRCA1 associated RING domain 1. (718 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (165 aa)
RNF2Ring finger protein 2. (336 aa)
LOC105527518RING-type domain-containing protein. (326 aa)
RYBPRING1 and YY1 binding protein. (230 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
DDB2Damage specific DNA binding protein 2. (427 aa)
ENSCANP00000033944Uncharacterized protein; Belongs to the SKP1 family. (131 aa)
PCGF3Polycomb group ring finger 3. (242 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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