23 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105502338	Heparanase 2 (inactive). (389 aa)
	SEMA5A	Semaphorin 5A. (1074 aa)
	COMP	Cartilage oligomeric matrix protein. (757 aa)
	AZU1	Azurocidin 1. (250 aa)
	FST	Follistatin. (317 aa)
	PLA2G2D	Phospholipase A(2). (145 aa)
	CFH	Uncharacterized protein. (1234 aa)
	HRG	Histidine rich glycoprotein. (526 aa)
	FGF20	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
	ENSCANP00000010624	Sushi domain-containing protein. (143 aa)
	PTPRS	Protein tyrosine phosphatase receptor type S. (1797 aa)
	LPL	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
	BMPER	BMP binding endothelial regulator. (685 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (1311 aa)
	AGRN	Agrin. (1697 aa)
	APOE	Apolipoprotein E. (189 aa)
	HPSE2	Uncharacterized protein. (149 aa)
	LRRTM3	Leucine rich repeat transmembrane neuronal 3. (581 aa)
	SLIT1	Slit guidance ligand 1. (1534 aa)
	FBLN7	Fibulin 7. (422 aa)
	LRRTM4	Leucine rich repeat transmembrane neuronal 4. (591 aa)
	ITGA2	Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
	LRP1	LDL receptor related protein 1. (4544 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGRN	APOE	ENSCANP00000018554	ENSCANP00000019437	Agrin.	Apolipoprotein E.	0.609
AGRN	LRP1	ENSCANP00000018554	ENSCANP00000039812	Agrin.	LDL receptor related protein 1.	0.781
AGRN	PTPRS	ENSCANP00000018554	ENSCANP00000010833	Agrin.	Protein tyrosine phosphatase receptor type S.	0.666
APOE	AGRN	ENSCANP00000019437	ENSCANP00000018554	Apolipoprotein E.	Agrin.	0.609
APOE	CFH	ENSCANP00000019437	ENSCANP00000009110	Apolipoprotein E.	Uncharacterized protein.	0.468
APOE	ENSCANP00000010624	ENSCANP00000019437	ENSCANP00000010624	Apolipoprotein E.	Sushi domain-containing protein.	0.468
APOE	LPL	ENSCANP00000019437	ENSCANP00000013730	Apolipoprotein E.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.942
APOE	LRP1	ENSCANP00000019437	ENSCANP00000039812	Apolipoprotein E.	LDL receptor related protein 1.	0.966
BMPER	FST	ENSCANP00000015050	ENSCANP00000006738	BMP binding endothelial regulator.	Follistatin.	0.407
CFH	APOE	ENSCANP00000009110	ENSCANP00000019437	Uncharacterized protein.	Apolipoprotein E.	0.468
COMP	ITGA2	ENSCANP00000005010	ENSCANP00000037945	Cartilage oligomeric matrix protein.	Integrin subunit alpha 2; Belongs to the integrin alpha chain family.	0.839
ENSCANP00000010624	APOE	ENSCANP00000010624	ENSCANP00000019437	Sushi domain-containing protein.	Apolipoprotein E.	0.468
FST	BMPER	ENSCANP00000006738	ENSCANP00000015050	Follistatin.	BMP binding endothelial regulator.	0.407
HPSE2	LOC105502338	ENSCANP00000020402	ENSCANP00000036173	Uncharacterized protein.	Heparanase 2 (inactive).	0.899
ITGA2	COMP	ENSCANP00000037945	ENSCANP00000005010	Integrin subunit alpha 2; Belongs to the integrin alpha chain family.	Cartilage oligomeric matrix protein.	0.839
ITGA2	PTPRC	ENSCANP00000037945	ENSCANP00000015789	Integrin subunit alpha 2; Belongs to the integrin alpha chain family.	Protein tyrosine phosphatase receptor type C.	0.466
LOC105502338	HPSE2	ENSCANP00000036173	ENSCANP00000020402	Heparanase 2 (inactive).	Uncharacterized protein.	0.899
LPL	APOE	ENSCANP00000013730	ENSCANP00000019437	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	Apolipoprotein E.	0.942
LPL	LRP1	ENSCANP00000013730	ENSCANP00000039812	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	LDL receptor related protein 1.	0.900
LRP1	AGRN	ENSCANP00000039812	ENSCANP00000018554	LDL receptor related protein 1.	Agrin.	0.781