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| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa) |
| | EDN3 | Endothelin 3. (230 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (648 aa) |
| | ELANE | Elastase, neutrophil expressed; Belongs to the peptidase S1 family. (265 aa) |
| | IL34 | Interleukin 34. (242 aa) |
| | KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa) |
| | THBS1 | Thrombospondin 1. (1173 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | AXIN1 | Axin 1. (859 aa) |
| | ARHGEF5 | Rho guanine nucleotide exchange factor 5. (1593 aa) |
| | TENM1 | Teneurin transmembrane protein 1. (2732 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (403 aa) |
| | MAP2K5 | Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1364 aa) |
| | RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (259 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (463 aa) |
| | ENSCANP00000026065 | Uncharacterized protein. (76 aa) |
| | FZD8 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (488 aa) |
| | NEK10 | NIMA related kinase 10. (1173 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (736 aa) |
| | FGD2 | FYVE, RhoGEF and PH domain containing 2. (654 aa) |
| | EDN1 | Endothelin 1. (211 aa) |
| | PIK3R6 | Phosphoinositide-3-kinase regulatory subunit 6. (709 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | LOC105519161 | CFC domain-containing protein. (170 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (468 aa) |
| | ENSCANP00000002034 | Uncharacterized protein. (114 aa) |
| | PLA2G1B | Phospholipase A(2). (147 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | ADAM9 | ADAM metallopeptidase domain 9. (819 aa) |
| | MIF | Uncharacterized protein. (114 aa) |
| | ENSCANP00000004126 | Uncharacterized protein. (79 aa) |
| | CD40 | CD40 molecule. (278 aa) |
| | ERN2 | Endoplasmic reticulum to nucleus signaling 2. (926 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | MAP4K2 | Mitogen-activated protein kinase kinase kinase kinase 2; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (797 aa) |
| | TGFA | Transforming growth factor alpha. (166 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (555 aa) |
| | NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (278 aa) |
| | MEF2C | Myocyte enhancer factor 2C. (483 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | PTPN1 | Tyrosine-protein phosphatase non-receptor type. (465 aa) |
| | DKK1 | Dickkopf WNT signaling pathway inhibitor 1. (266 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1259 aa) |
| | ERP29 | Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase. (260 aa) |
| | ENSCANP00000008716 | Uncharacterized protein. (216 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (336 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (481 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) |
| | PDE5A | Phosphodiesterase. (875 aa) |
| | CSK | Tyrosine-protein kinase. (450 aa) |
| | AKAP13 | A-kinase anchoring protein 13. (2812 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | PDCD10 | Uncharacterized protein. (212 aa) |
| | TAOK3 | TAO kinase 3. (898 aa) |
| | TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (317 aa) |
| | ROR2 | Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1079 aa) |
| | TNFRSF11A | TNF receptor superfamily member 11a. (712 aa) |
| | PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (879 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (220 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1311 aa) |
| | DAB2IP | DAB2 interacting protein. (1155 aa) |
| | MAP3K4 | Mitogen-activated protein kinase kinase kinase 4. (1586 aa) |
| | CCL19 | C-C motif chemokine. (104 aa) |
| | ROBO1 | Roundabout guidance receptor 1. (1598 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa) |
| | ERN1 | Endoplasmic reticulum to nucleus signaling 1. (979 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | ENSCANP00000017887 | Uncharacterized protein. (146 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1188 aa) |
| | ENSCANP00000018729 | Uncharacterized protein. (108 aa) |
| | MAP3K13 | Mitogen-activated protein kinase kinase kinase 13. (700 aa) |
| | MAP3K10 | Mitogen-activated protein kinase kinase kinase 10. (777 aa) |
| | SRC | Tyrosine-protein kinase. (458 aa) |
| | MST1R | Macrophage stimulating 1 receptor. (1400 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa) |
| | ENSCANP00000029034 | Uncharacterized protein. (145 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1255 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1040 aa) |
| | NTRK3 | Tyrosine-protein kinase receptor. (865 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (793 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (838 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | TDGF1 | Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (171 aa) |
| | LRRK2 | Leucine rich repeat kinase 2. (2527 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | MAP3K11 | Mitogen-activated protein kinase kinase kinase. (847 aa) |
| | EPHA4 | EPH receptor A4. (986 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1388 aa) |
| | FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (995 aa) |
| | LOC105501854 | Ribosomal_S3_C domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (252 aa) |
| | DUSP19 | Dual specificity phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (217 aa) |
| | TPD52L1 | TPD52 like 1. (221 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa) |
| | SASH1 | SAM and SH3 domain containing 1. (1241 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (815 aa) |
| | AJUBA | Ajuba LIM protein. (538 aa) |
| | MAP3K12 | Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (890 aa) |
| | EPGN | Epithelial mitogen. (154 aa) |
| | ENSCANP00000038043 | Uncharacterized protein. (107 aa) |
| | CD24 | Uncharacterized protein. (127 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | LOC105503257 | Uncharacterized protein. (194 aa) |
| | MAGED1 | MAGE family member D1. (810 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | DVL3 | Dishevelled segment polarity protein 3. (716 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) |
