(40 nodes) Inositol phosphate metabolic process network (Colobus angolensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	INPP1	Inositol polyphosphate-1-phosphatase. (399 aa)
	LOC105514970	Nudix hydrolase domain-containing protein. (160 aa)
	IPMK	Kinase; Belongs to the inositol phosphokinase (IPK) family. (416 aa)
	INPP5J	Inositol polyphosphate-5-phosphatase J. (1001 aa)
	BPNT1	3'(2'), 5'-bisphosphate nucleotidase 1. (347 aa)
	IP6K2	Kinase; Belongs to the inositol phosphokinase (IPK) family. (473 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
	IP6K1	Kinase; Belongs to the inositol phosphokinase (IPK) family. (441 aa)
	INPP5K	Inositol polyphosphate-5-phosphatase K. (456 aa)
	ITPKC	Kinase; Belongs to the inositol phosphokinase (IPK) family. (611 aa)
	ENSCANP00000027128	Inositol-1-monophosphatase. (223 aa)
	IMPA2	Uncharacterized protein. (99 aa)
	LOC105514972	Nudix hydrolase domain-containing protein. (188 aa)
	NUDT3	Nudix hydrolase 3. (172 aa)
	NTSR1	Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (418 aa)
	INPP5B	Inositol polyphosphate-5-phosphatase B. (950 aa)
	SYNJ1	Synaptojanin 1. (1614 aa)
	ITPKB	Kinase; Belongs to the inositol phosphokinase (IPK) family. (945 aa)
	OCRL	OCRL inositol polyphosphate-5-phosphatase. (892 aa)
	INPP5A	Inositol polyphosphate-5-phosphatase A. (393 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1257 aa)
	ENSCANP00000002525	Uncharacterized protein. (81 aa)
	PTAFR	Platelet activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (342 aa)
	SCP2	Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)
	PSORS1C2	Psoriasis susceptibility 1 candidate 2. (136 aa)
	IPPK	Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (491 aa)
	IMPAD1	Inositol monophosphatase domain containing 1. (359 aa)
	IP6K3	Kinase; Belongs to the inositol phosphokinase (IPK) family. (410 aa)
	IMPA1	Inositol-1-monophosphatase. (310 aa)
	MTMR7	Myotubularin related protein 7. (660 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1173 aa)
	MTMR2	Myotubularin related protein 2. (643 aa)
	INPP5E	Inositol polyphosphate-5-phosphatase E. (573 aa)
	MINPP1	Multiple inositol-polyphosphate phosphatase 1; Belongs to the histidine acid phosphatase family. (487 aa)
	GALR2	Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family. (387 aa)
	SYNJ2	Synaptojanin 2. (1459 aa)
	NUDT4	Nudix hydrolase domain-containing protein. (180 aa)
	ITPKA	Kinase; Belongs to the inositol phosphokinase (IPK) family. (298 aa)
	INPP4A	Inositol polyphosphate-4-phosphatase type I A. (977 aa)
	ITPK1	Inositol-tetrakisphosphate 1-kinase. (414 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BPNT1	ENSCANP00000027128	ENSCANP00000011003	ENSCANP00000027128	3'(2'), 5'-bisphosphate nucleotidase 1.	Inositol-1-monophosphatase.	0.561
BPNT1	IMPA1	ENSCANP00000011003	ENSCANP00000036957	3'(2'), 5'-bisphosphate nucleotidase 1.	Inositol-1-monophosphatase.	0.561
BPNT1	IMPA2	ENSCANP00000011003	ENSCANP00000026964	3'(2'), 5'-bisphosphate nucleotidase 1.	Uncharacterized protein.	0.561
BPNT1	IMPAD1	ENSCANP00000011003	ENSCANP00000007460	3'(2'), 5'-bisphosphate nucleotidase 1.	Inositol monophosphatase domain containing 1.	0.835
BPNT1	INPP4A	ENSCANP00000011003	ENSCANP00000030290	3'(2'), 5'-bisphosphate nucleotidase 1.	Inositol polyphosphate-4-phosphatase type I A.	0.472
ENSCANP00000002525	IP6K1	ENSCANP00000002525	ENSCANP00000009703	Uncharacterized protein.	Kinase; Belongs to the inositol phosphokinase (IPK) family.	0.890
ENSCANP00000002525	IP6K2	ENSCANP00000002525	ENSCANP00000010935	Uncharacterized protein.	Kinase; Belongs to the inositol phosphokinase (IPK) family.	0.885
ENSCANP00000002525	IP6K3	ENSCANP00000002525	ENSCANP00000007625	Uncharacterized protein.	Kinase; Belongs to the inositol phosphokinase (IPK) family.	0.888
ENSCANP00000002525	IPPK	ENSCANP00000002525	ENSCANP00000006138	Uncharacterized protein.	Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).	0.866
ENSCANP00000027128	BPNT1	ENSCANP00000027128	ENSCANP00000011003	Inositol-1-monophosphatase.	3'(2'), 5'-bisphosphate nucleotidase 1.	0.561
ENSCANP00000027128	IMPA2	ENSCANP00000027128	ENSCANP00000026964	Inositol-1-monophosphatase.	Uncharacterized protein.	0.847
ENSCANP00000027128	IMPAD1	ENSCANP00000027128	ENSCANP00000007460	Inositol-1-monophosphatase.	Inositol monophosphatase domain containing 1.	0.777
ENSCANP00000027128	INPP1	ENSCANP00000027128	ENSCANP00000016940	Inositol-1-monophosphatase.	Inositol polyphosphate-1-phosphatase.	0.753
ENSCANP00000027128	INPP4A	ENSCANP00000027128	ENSCANP00000030290	Inositol-1-monophosphatase.	Inositol polyphosphate-4-phosphatase type I A.	0.640
ENSCANP00000027128	PLCB1	ENSCANP00000027128	ENSCANP00000036437	Inositol-1-monophosphatase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.649
IMPA1	BPNT1	ENSCANP00000036957	ENSCANP00000011003	Inositol-1-monophosphatase.	3'(2'), 5'-bisphosphate nucleotidase 1.	0.561
IMPA1	IMPA2	ENSCANP00000036957	ENSCANP00000026964	Inositol-1-monophosphatase.	Uncharacterized protein.	0.920
IMPA1	IMPAD1	ENSCANP00000036957	ENSCANP00000007460	Inositol-1-monophosphatase.	Inositol monophosphatase domain containing 1.	0.870
IMPA1	INPP1	ENSCANP00000036957	ENSCANP00000016940	Inositol-1-monophosphatase.	Inositol polyphosphate-1-phosphatase.	0.876
IMPA1	INPP4A	ENSCANP00000036957	ENSCANP00000030290	Inositol-1-monophosphatase.	Inositol polyphosphate-4-phosphatase type I A.	0.771