STRINGSTRING
RHOC RHOC SRC SRC ARL2 ARL2 JUP JUP MUC22 MUC22 CNTNAP1 CNTNAP1 ANK2 ANK2 CDH6 CDH6 NECTIN1 NECTIN1 PLEKHA7 PLEKHA7 TBCD TBCD AMOT AMOT GNPAT GNPAT CTNND2 CTNND2 F2R F2R DLG1 DLG1 XIRP2 XIRP2 CTNNA1 CTNNA1 POF1B POF1B EPHA4 EPHA4 NUMB NUMB RAMP2 RAMP2 ENSCANP00000033512 ENSCANP00000033512 CTNND1 CTNND1 CDHR3 CDHR3 KIFC3 KIFC3 STRN STRN OCLN OCLN CDH22 CDH22 TGFB3 TGFB3 AFDN AFDN ECT2 ECT2 EPHB2 EPHB2 MARVELD2 MARVELD2 WHRN WHRN CLDN11 CLDN11 ADAM10 ADAM10 PAK2 PAK2 CDH8 CDH8 GRHL2 GRHL2 CDH2 CDH2 SVEP1 SVEP1 PLEC PLEC NLGN2 NLGN2 FBF1 FBF1 CDH24 CDH24 SRF SRF PKP1 PKP1 RAB13 RAB13 CDH18 CDH18 LOC105521231 LOC105521231 KIRREL1 KIRREL1 CD177 CD177 FER FER TLN1 TLN1 EXT1 EXT1 CLDN18 CLDN18 LOC105527362 LOC105527362 MTSS1 MTSS1 TLN2 TLN2 FLNA FLNA CCM2 CCM2 SHROOM2 SHROOM2 FRMPD2 FRMPD2 ARVCF ARVCF PMP22 PMP22 EFNB2 EFNB2 JAM3 JAM3 CDH1 CDH1 TJP3 TJP3 FERMT2 FERMT2 CDH5 CDH5 ZNF703 ZNF703 ENSCANP00000021244 ENSCANP00000021244 PKHD1 PKHD1 PECAM1 PECAM1 TGFB2 TGFB2 CXADR CXADR NUMBL NUMBL LOC105524240 LOC105524240 PDCD6IP PDCD6IP ENSCANP00000018773 ENSCANP00000018773 CDH11 CDH11 ENSCANP00000017605 ENSCANP00000017605 CAMSAP3 CAMSAP3 CDH12 CDH12 LSR LSR CSF1R CSF1R PRKCI PRKCI LIMS2 LIMS2 LIM2 LIM2 INAVA INAVA CDH7 CDH7 WDR1 WDR1 CLDN19 CLDN19 HEG1 HEG1 SNAI2 SNAI2 FLCN FLCN DSG2 DSG2 WNT11 WNT11 PARD3 PARD3 EPB41L3 EPB41L3 CTNNB1 CTNNB1 CDH20 CDH20 CSK CSK CD9 CD9 VCL VCL PERP PERP DSP DSP TGFB1 TGFB1 CDH19 CDH19 DCHS1 DCHS1 RHOA RHOA TJP1 TJP1 APC APC CDH10 CDH10 MPP7 MPP7 PKP3 PKP3 PTPRO PTPRO SMAD7 SMAD7 CLDN15 CLDN15 CLDN24 CLDN24 CLDN2 CLDN2 CDH9 CDH9 MPZ MPZ CLDN16 CLDN16 CLDN1 CLDN1 CLDN7 CLDN7 CLDN3 CLDN3 NF2 NF2 PATJ PATJ CLDN4 CLDN4 TRPV4 TRPV4 GJB6 GJB6 DLG5 DLG5 FSCN1 FSCN1 GJB2 GJB2 GJB1 GJB1 PARD6A PARD6A HIPK1 HIPK1 CLDN8 CLDN8 NR1H4 NR1H4 HDAC7 HDAC7 PRKCA PRKCA PKP4 PKP4 UGT8 UGT8 CLDN17 CLDN17 GJA5 GJA5 CLDN14 CLDN14 LOC105502368 LOC105502368 CLDN9 CLDN9 LIMS1 LIMS1 PIP5K1C PIP5K1C DSG1 DSG1 GJC1 GJC1 NPHS1 NPHS1 CLDN20 CLDN20 PKN2 PKN2 SMAD3 SMAD3 PKP2 PKP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RHOCRas homolog family member C. (193 aa)
SRCTyrosine-protein kinase. (458 aa)
ARL2ADP ribosylation factor like GTPase 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
JUPJunction plakoglobin. (746 aa)
MUC22Mucin 22. (1455 aa)
CNTNAP1Contactin associated protein 1. (1364 aa)
ANK2Ankyrin 2. (3938 aa)
CDH6Cadherin 6; Cadherins are calcium-dependent cell adhesion proteins. (790 aa)
NECTIN1Nectin cell adhesion molecule 1. (516 aa)
PLEKHA7Pleckstrin homology domain containing A7. (1197 aa)
TBCDTubulin folding cofactor D. (1166 aa)
AMOTAngiomotin. (1084 aa)
GNPATDihydroxyacetone phosphate acyltransferase. (680 aa)
CTNND2Catenin delta 2. (1129 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (413 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa)
XIRP2Xin actin binding repeat containing 2. (3549 aa)
CTNNA1Catenin alpha 1. (906 aa)
POF1BUncharacterized protein. (304 aa)
EPHA4EPH receptor A4. (986 aa)
NUMBNUMB endocytic adaptor protein. (652 aa)
RAMP2Receptor activity modifying protein 2. (216 aa)
ENSCANP00000033512Uncharacterized protein. (152 aa)
CTNND1Catenin delta 1. (968 aa)
CDHR3Cadherin related family member 3. (844 aa)
KIFC3Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (833 aa)
STRNStriatin. (630 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (522 aa)
CDH22Cadherin 22; Cadherins are calcium-dependent cell adhesion proteins. (784 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
AFDNAfadin, adherens junction formation factor. (1809 aa)
ECT2Epithelial cell transforming 2. (904 aa)
EPHB2EPH receptor B2. (1082 aa)
MARVELD2MARVEL domain containing 2. (559 aa)
WHRNWhirlin. (907 aa)
CLDN11Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
CDH8Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins. (799 aa)
GRHL2Grainyhead like transcription factor 2. (625 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (890 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1. (3571 aa)
PLECPlectin. (4128 aa)
NLGN2Neuroligin 2. (733 aa)
FBF1Fas binding factor 1. (1141 aa)
CDH24Cadherin 24; Cadherins are calcium-dependent cell adhesion proteins. (655 aa)
SRFSerum response factor. (406 aa)
PKP1Plakophilin 1. (733 aa)
RAB13Uncharacterized protein. (203 aa)
CDH18Cadherin 18; Cadherins are calcium-dependent cell adhesion proteins. (790 aa)
LOC105521231Uncharacterized protein; Belongs to the actin family. (376 aa)
KIRREL1Kirre like nephrin family adhesion molecule 1. (758 aa)
CD177CD177 molecule. (462 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
TLN1Talin 1. (2559 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
LOC105527362Uncharacterized protein. (835 aa)
MTSS1MTSS I-BAR domain containing 1. (727 aa)
TLN2Talin 2. (2544 aa)
FLNAFilamin A. (2647 aa)
CCM2CCM2 scaffold protein. (466 aa)
SHROOM2Shroom family member 2. (1561 aa)
FRMPD2FERM and PDZ domain containing 2. (1398 aa)
ARVCFARVCF delta catenin family member. (962 aa)
PMP22Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system; Belongs to the PMP-22/EMP/MP20 family. (160 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (335 aa)
JAM3Junctional adhesion molecule 3. (301 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (770 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (910 aa)
FERMT2Fermitin family member 2. (687 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (717 aa)
ZNF703Zinc finger protein 703. (567 aa)
ENSCANP00000021244Uncharacterized protein. (198 aa)
PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4073 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (646 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
CXADRCXADR Ig-like cell adhesion molecule. (365 aa)
NUMBLNUMB like endocytic adaptor protein. (551 aa)
LOC105524240Uncharacterized protein. (370 aa)
PDCD6IPBRO1 domain-containing protein. (903 aa)
ENSCANP00000018773PDZ domain-containing protein. (299 aa)
CDH11Cadherin 11; Cadherins are calcium-dependent cell adhesion proteins. (796 aa)
ENSCANP00000017605Uncharacterized protein; Belongs to the actin family. (163 aa)
CAMSAP3Calmodulin regulated spectrin associated protein family member 3. (1200 aa)
CDH12Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
LSRLipolysis stimulated lipoprotein receptor. (754 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (974 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (355 aa)
LIM2Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family. (215 aa)
INAVAInnate immunity activator. (663 aa)
CDH7Cadherin 7; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
WDR1WD repeat domain 1. (560 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
HEG1Heart development protein with EGF like domains 1. (1274 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
FLCNFolliculin. (579 aa)
DSG2Desmoglein 2. (1118 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
PARD3Par-3 family cell polarity regulator. (1316 aa)
EPB41L3Erythrocyte membrane protein band 4.1 like 3. (1087 aa)
CTNNB1Catenin beta 1. (781 aa)
CDH20Cadherin 20; Cadherins are calcium-dependent cell adhesion proteins. (801 aa)
CSKTyrosine-protein kinase. (450 aa)
CD9Tetraspanin. (228 aa)
VCLVinculin. (1135 aa)
PERPP53 apoptosis effector related to PMP22. (193 aa)
DSPDesmoplakin. (2510 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (336 aa)
CDH19Cadherin 19; Cadherins are calcium-dependent cell adhesion proteins. (772 aa)
DCHS1Dachsous cadherin-related 1. (3302 aa)
RHOARas homolog family member A. (193 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1762 aa)
APCAPC regulator of WNT signaling pathway. (2843 aa)
CDH10Cadherin 10; Cadherins are calcium-dependent cell adhesion proteins. (788 aa)
MPP7Membrane palmitoylated protein 7; Belongs to the MAGUK family. (576 aa)
PKP3Plakophilin 3. (714 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1216 aa)
SMAD7Mothers against decapentaplegic homolog. (431 aa)
CLDN15Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (228 aa)
CLDN24Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
CLDN2Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa)
CDH9Cadherin 9; Cadherins are calcium-dependent cell adhesion proteins. (789 aa)
MPZMyelin protein zero. (248 aa)
CLDN16Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (304 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
NF2Neurofibromin 2. (561 aa)
PATJPATJ crumbs cell polarity complex component. (1778 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
GJB6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (261 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1896 aa)
FSCN1Fascin. (493 aa)
GJB2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (226 aa)
GJB1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (283 aa)
PARD6APar-6 family cell polarity regulator alpha. (345 aa)
HIPK1Homeodomain interacting protein kinase 1. (1210 aa)
CLDN8Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (486 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1002 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
PKP4Plakophilin 4. (1192 aa)
UGT8UDP glycosyltransferase 8; Belongs to the UDP-glycosyltransferase family. (541 aa)
CLDN17Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
CLDN14Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (239 aa)
LOC105502368Uncharacterized protein. (372 aa)
CLDN9Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
LIMS1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (398 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (665 aa)
DSG1Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1038 aa)
GJC1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (396 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1240 aa)
CLDN20Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
PKN2Protein kinase N2. (983 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
PKP2Plakophilin 2. (882 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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