STRINGSTRING
RAD21 RAD21 MTBP MTBP ZWILCH ZWILCH SPC24 SPC24 BUB1 BUB1 BIRC5 BIRC5 MAD2L2 MAD2L2 AURKB AURKB ENSCANP00000004751 ENSCANP00000004751 TRIP13 TRIP13 APC APC PLK1 PLK1 NME6 NME6 MAD1L1 MAD1L1 SPC25 SPC25 ZWINT ZWINT BUB1B BUB1B MAD2L1 MAD2L1 TPR TPR NUF2 NUF2 ZW10 ZW10 TOM1L1 TOM1L1 TEX14 TEX14 AURKAIP1 AURKAIP1 PSMG2 PSMG2 CDC20 CDC20 ENSCANP00000034448 ENSCANP00000034448 TOM1L2 TOM1L2 BMP4 BMP4 ENSCANP00000012968 ENSCANP00000012968 CENPF CENPF ATM ATM SPDL1 SPDL1 BMP7 BMP7 KLHL22 KLHL22 KNTC1 KNTC1 FBXO5 FBXO5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAD21RAD21 cohesin complex component. (631 aa)
MTBPMDM2 binding protein. (868 aa)
ZWILCHZwilch kinetochore protein. (591 aa)
SPC24SPC24 component of NDC80 kinetochore complex. (197 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1096 aa)
BIRC5Baculoviral IAP repeat containing 5. (147 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (210 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (345 aa)
ENSCANP00000004751Rad21_Rec8 domain-containing protein. (148 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (432 aa)
APCAPC regulator of WNT signaling pathway. (2843 aa)
PLK1Serine/threonine-protein kinase PLK. (603 aa)
NME6Nucleoside diphosphate kinase. (186 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (725 aa)
SPC25SPC25 component of NDC80 kinetochore complex. (224 aa)
ZWINTZW10 interacting kinetochore protein. (230 aa)
BUB1BBUB1 N-terminal domain-containing protein. (1046 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (205 aa)
TPRTranslocated promoter region, nuclear basket protein. (2363 aa)
NUF2NUF2 component of NDC80 kinetochore complex. (464 aa)
ZW10Zw10 kinetochore protein. (778 aa)
TOM1L1Target of myb1 like 1 membrane trafficking protein; Belongs to the TOM1 family. (398 aa)
TEX14Testis expressed 14, intercellular bridge forming factor. (1392 aa)
AURKAIP1Aurora kinase A interacting protein 1. (199 aa)
PSMG2Proteasome assembly chaperone 2; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. Belongs to the PSMG2 family. (264 aa)
CDC20Cell division cycle 20. (499 aa)
ENSCANP00000034448RED_C domain-containing protein. (146 aa)
TOM1L2Target of myb1 like 2 membrane trafficking protein; Belongs to the TOM1 family. (507 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
ENSCANP00000012968Uncharacterized protein. (533 aa)
CENPFCentromere protein F. (3114 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (558 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
KLHL22Kelch like family member 22. (634 aa)
KNTC1Kinetochore associated 1. (2159 aa)
FBXO5F-box protein 5. (448 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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