STRINGSTRING
SMURF2 SMURF2 CITED1 CITED1 PPM1A PPM1A SMAD3 SMAD3 AXIN2 AXIN2 MEN1 MEN1 STUB1 STUB1 RANBP3L RANBP3L ENSCANP00000003939 ENSCANP00000003939 TGFBR2 TGFBR2 SMAD7 SMAD7 LOC105509188 LOC105509188 SAV1 SAV1 PML PML BMPR1B BMPR1B SKIL SKIL SMAD9 SMAD9 HIPK2 HIPK2 ACVRL1 ACVRL1 COL1A2 COL1A2 USP9X USP9X RANBP3 RANBP3 CTNNB1 CTNNB1 FOXH1 FOXH1 ENSCANP00000012853 ENSCANP00000012853 ACVR1 ACVR1 BMP2 BMP2 DAB2 DAB2 BMPR1A BMPR1A USP15 USP15 SNW1 SNW1 TGFBR3 TGFBR3 HMGA2 HMGA2 COL5A2 COL5A2 ENSCANP00000016476 ENSCANP00000016476 PMEPA1 PMEPA1 ZC3H3 ZC3H3 SMAD1 SMAD1 RGCC RGCC IPO7 IPO7 FOS FOS CITED2 CITED2 COL3A1 COL3A1 ZMIZ1 ZMIZ1 FERMT2 FERMT2 AXIN1 AXIN1 ACVR1B ACVR1B ENSCANP00000023391 ENSCANP00000023391 MEF2A MEF2A DROSHA DROSHA INTS8 INTS8 TGFB1I1 TGFB1I1 MYOCD MYOCD PAX6 PAX6 CREB3L1 CREB3L1 SMURF1 SMURF1 SMAD4 SMAD4 LDLRAD4 LDLRAD4 DDX5 DDX5 TGFBR1 TGFBR1 SKOR1 SKOR1 JUN JUN SKI SKI MAGI2 MAGI2 TRIM33 TRIM33 PARP1 PARP1 TCF12 TCF12 SMAD2 SMAD2 GATA4 GATA4 ANKRD1 ANKRD1 TGFBRAP1 TGFBRAP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMURF2E3 ubiquitin-protein ligase. (734 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
AXIN2Axin 2. (843 aa)
MEN1Menin 1. (610 aa)
STUB1STIP1 homology and U-box containing protein 1. (250 aa)
RANBP3LRAN binding protein 3 like. (488 aa)
ENSCANP00000003939PPM-type phosphatase domain-containing protein. (346 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
SMAD7Mothers against decapentaplegic homolog. (431 aa)
LOC105509188Uncharacterized protein. (835 aa)
SAV1Salvador family WW domain containing protein 1. (384 aa)
PMLPromyelocytic leukemia. (882 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SKILSKI like proto-oncogene. (684 aa)
SMAD9Mothers against decapentaplegic homolog. (467 aa)
HIPK2Homeodomain interacting protein kinase 2. (1197 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
USP9XUbiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2418 aa)
RANBP3RAN binding protein 3. (569 aa)
CTNNB1Catenin beta 1. (781 aa)
FOXH1Forkhead box H1. (366 aa)
ENSCANP00000012853C2 domain-containing protein. (51 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
DAB2DAB adaptor protein 2. (770 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
SNW1SNW domain containing 1. (571 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
HMGA2High mobility group AT-hook 2. (147 aa)
COL5A2Collagen type V alpha 2 chain. (1499 aa)
ENSCANP00000016476c-SKI_SMAD_bind domain-containing protein. (295 aa)
PMEPA1Prostate transmembrane protein, androgen induced 1. (259 aa)
ZC3H3Zinc finger CCCH-type containing 3. (948 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
RGCCRegulator of cell cycle. (208 aa)
IPO7Importin 7. (952 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1067 aa)
FERMT2Fermitin family member 2. (687 aa)
AXIN1Axin 1. (859 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
ENSCANP00000023391Uncharacterized protein. (356 aa)
MEF2AMyocyte enhancer factor 2A. (512 aa)
DROSHADrosha ribonuclease III. (1369 aa)
INTS8Integrator complex subunit 8. (898 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa)
MYOCDMyocardin. (923 aa)
PAX6Paired box 6. (478 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
SMURF1E3 ubiquitin-protein ligase. (763 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
LDLRAD4Low density lipoprotein receptor class A domain containing 4. (306 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
SKOR1SKI family transcriptional corepressor 1. (871 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (246 aa)
SKISKI proto-oncogene. (649 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1259 aa)
TRIM33Tripartite motif containing 33. (1046 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
TCF12Transcription factor 12. (706 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
GATA4GATA binding protein 4. (236 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
TGFBRAP1Transforming growth factor beta receptor associated protein 1. (860 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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