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ACVR2A ACVR2A NUPR1 NUPR1 ARID5B ARID5B LHCGR LHCGR CTNNB1 CTNNB1 ING2 ING2 ACE ACE AR AR TFPT TFPT STAT5B STAT5B HOXA13 HOXA13 LOC105517216 LOC105517216 LHFPL2 LHFPL2 BMPR1A BMPR1A ROR2 ROR2 SOX8 SOX8 TBX3 TBX3 CSMD2 CSMD2 PRDX4 PRDX4 LOC105504658 LOC105504658 SPATA2 SPATA2 HOXD13 HOXD13 RARA RARA KIF18A KIF18A SYCP2 SYCP2 BRIP1 BRIP1 SFRP2 SFRP2 ATRX ATRX ATN1 ATN1 ASPM ASPM FGF9 FGF9 CITED2 CITED2 AKR1C3 AKR1C3 RHOBTB3 RHOBTB3 RNF38 RNF38 AMHR2 AMHR2 TGFB2 TGFB2 SIX4 SIX4 KITLG KITLG REC8 REC8 LOC105527342 LOC105527342 GREB1 GREB1 ARID4A ARID4A CSDE1 CSDE1 COL9A3 COL9A3 GATA3 GATA3 HOXA10 HOXA10 SCAPER SCAPER BIK BIK LOC105527362 LOC105527362 FER FER MAMLD1 MAMLD1 NR0B1 NR0B1 FKBP4 FKBP4 ASB1 ASB1 RAB13 RAB13 YBX3 YBX3 WNT4 WNT4 LRRC6 LRRC6 WDR48 WDR48 TESC TESC REN REN WT1 WT1 BAX BAX ERCC1 ERCC1 SMAD4 SMAD4 TGFBR1 TGFBR1 NTRK1 NTRK1 CSMD1 CSMD1 INHA INHA CRKL CRKL SHH SHH TFAP2C TFAP2C NUP210L NUP210L WNT5A WNT5A LHX9 LHX9 WNT2B WNT2B LRP2 LRP2 ENSCANP00000033948 ENSCANP00000033948 SOX9 SOX9 HSD17B3 HSD17B3 TLR3 TLR3 CTNNA1 CTNNA1 TMF1 TMF1 TEX11 TEX11 NUDT1 NUDT1 ESR1 ESR1 KIT KIT DMRT1 DMRT1 SF1 SF1 FANCA FANCA GATA4 GATA4 ADAM15 ADAM15 NR5A1 NR5A1 CBL CBL KLHL10 KLHL10 PLEKHA1 PLEKHA1 CYP1B1 CYP1B1 SGPL1 SGPL1 NKX3-1 NKX3-1 BCL2L11 BCL2L11 FSHR FSHR GATA1 GATA1 BMP6 BMP6 FGF8 FGF8 PDGFRB PDGFRB ARID4B ARID4B FGF10 FGF10 RXFP2 RXFP2 BMP5 BMP5 MSH2 MSH2 GREB1L GREB1L SDC1 SDC1 PATZ1 PATZ1 SAFB2 SAFB2 TBC1D20 TBC1D20 GFRA1 GFRA1 MAS1 MAS1 HOXA11 HOXA11 NCOA4 NCOA4 BOK BOK SRD5A2 SRD5A2 GATA6 GATA6 INHBA INHBA AGO4 AGO4 LGR4 LGR4 TNFSF10 TNFSF10 BCL2 BCL2 NHLH2 NHLH2 FNDC3A FNDC3A NASP NASP LOC105517215 LOC105517215 DMRT3 DMRT3 ENSCANP00000003346 ENSCANP00000003346 TCF21 TCF21 HSD17B4 HSD17B4 SOX15 SOX15 WNT9B WNT9B ADAM21 ADAM21 KDM5A KDM5A BCL2L1 BCL2L1 LOC105517331 LOC105517331 DHH DHH SFRP1 SFRP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (100 aa)
ARID5BAT-rich interaction domain 5B. (1156 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (699 aa)
CTNNB1Catenin beta 1. (781 aa)
ING2Inhibitor of growth protein. (280 aa)
ACEAngiotensin-converting enzyme. (1223 aa)
ARAndrogen receptor. (897 aa)
TFPTTCF3 fusion partner. (253 aa)
STAT5BSignal transducer and activator of transcription. (756 aa)
HOXA13Homeobox A13. (244 aa)
LOC105517216Uncharacterized protein. (685 aa)
LHFPL2LHFPL tetraspan subfamily member 2. (228 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1079 aa)
SOX8SRY-box transcription factor 8. (384 aa)
TBX3T-box transcription factor 3. (743 aa)
CSMD2CUB and Sushi multiple domains 2. (3537 aa)
PRDX4Peroxiredoxin 4. (271 aa)
LOC105504658Uncharacterized protein. (571 aa)
SPATA2Spermatogenesis associated 2. (520 aa)
HOXD13Homeobox D13. (303 aa)
RARARetinoic acid receptor alpha. (478 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (897 aa)
SYCP2Synaptonemal complex protein 2. (1527 aa)
BRIP1BRCA1 interacting protein C-terminal helicase 1. (1247 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
ATRXATRX chromatin remodeler. (2490 aa)
ATN1Atrophin 1. (1180 aa)
ASPMAbnormal spindle microtubule assembly. (3477 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
AKR1C3Aldo-keto reductase family 1 member C3. (323 aa)
RHOBTB3Rho related BTB domain containing 3. (611 aa)
RNF38Ring finger protein 38. (517 aa)
AMHR2Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. (573 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
SIX4SIX homeobox 4. (780 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
REC8REC8 meiotic recombination protein. (544 aa)
LOC105527342LRRNT domain-containing protein. (125 aa)
GREB1Growth regulating estrogen receptor binding 1. (1949 aa)
ARID4AAT-rich interaction domain 4A. (1280 aa)
CSDE1Uncharacterized protein. (844 aa)
COL9A3Uncharacterized protein. (742 aa)
GATA3GATA binding protein 3. (444 aa)
HOXA10Homeobox domain-containing protein. (94 aa)
SCAPERS-phase cyclin A associated protein in the ER. (1404 aa)
BIKBCL2 interacting killer. (160 aa)
LOC105527362Uncharacterized protein. (835 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
MAMLD1Mastermind like domain containing 1. (990 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (470 aa)
FKBP4Peptidylprolyl isomerase. (424 aa)
ASB1Ankyrin repeat and SOCS box containing 1. (342 aa)
RAB13Uncharacterized protein. (203 aa)
YBX3Y-box binding protein 3. (315 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (345 aa)
LRRC6Leucine rich repeat containing 6. (536 aa)
WDR48WD repeat domain 48. (677 aa)
TESCTescalcin. (210 aa)
RENRenin; Belongs to the peptidase A1 family. (406 aa)
WT1WT1 transcription factor. (517 aa)
BAXBCL2 associated X, apoptosis regulator. (198 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (298 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
CSMD1CUB and Sushi multiple domains 1. (3565 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
SHHSonic hedgehog signaling molecule. (390 aa)
TFAP2CTranscription factor AP-2 gamma. (401 aa)
NUP210LNucleoporin 210 like. (1734 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
LHX9LIM homeobox 9. (397 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
LRP2LDL receptor related protein 2. (4655 aa)
ENSCANP00000033948Homeobox domain-containing protein. (141 aa)
SOX9SRY-box transcription factor 9. (509 aa)
HSD17B3Hydroxysteroid 17-beta dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (310 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa)
CTNNA1Catenin alpha 1. (906 aa)
TMF1TATA element modulatory factor 1. (943 aa)
TEX11Testis expressed 11. (923 aa)
NUDT1Nudix hydrolase 1. (124 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
DMRT1Doublesex and mab-3 related transcription factor 1. (373 aa)
SF1Splicing factor 1. (639 aa)
FANCAFA complementation group A. (1360 aa)
GATA4GATA binding protein 4. (236 aa)
ADAM15ADAM metallopeptidase domain 15. (844 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (461 aa)
CBLCbl proto-oncogene. (888 aa)
KLHL10Kelch like family member 10. (608 aa)
PLEKHA1Pleckstrin homology domain containing A1. (404 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
NKX3-1NK3 homeobox 1. (232 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (570 aa)
GATA1GATA binding protein 1. (413 aa)
BMP6Bone morphogenetic protein 6. (331 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
ARID4BAT-rich interaction domain 4B. (1262 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
RXFP2Relaxin family peptide receptor 2. (748 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (904 aa)
GREB1LGREB1 like retinoic acid receptor coactivator. (1924 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (288 aa)
PATZ1POZ/BTB and AT hook containing zinc finger 1. (687 aa)
SAFB2Scaffold attachment factor B2. (930 aa)
TBC1D20TBC1 domain family member 20. (401 aa)
GFRA1GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. (467 aa)
MAS1MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (325 aa)
HOXA11Homeobox A11. (312 aa)
NCOA4Nuclear receptor coactivator 4. (650 aa)
BOKBCL2 family apoptosis regulator BOK. (171 aa)
SRD5A23-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (254 aa)
GATA6GATA binding protein 6. (462 aa)
INHBAInhibin subunit beta A. (426 aa)
AGO4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (855 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (932 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (281 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
NHLH2Nescient helix-loop-helix 2. (135 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
NASPNuclear autoantigenic sperm protein. (733 aa)
LOC105517215Uncharacterized protein. (680 aa)
DMRT3Doublesex and mab-3 related transcription factor 3. (432 aa)
ENSCANP00000003346Uncharacterized protein. (126 aa)
TCF21Transcription factor 21. (179 aa)
HSD17B4Hydroxysteroid 17-beta dehydrogenase 4. (754 aa)
SOX15SRY-box transcription factor 15. (233 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
ADAM21Uncharacterized protein. (722 aa)
KDM5ALysine demethylase 5A. (1690 aa)
BCL2L1BCL2 like 1. (233 aa)
LOC105517331Uncharacterized protein. (693 aa)
DHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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