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| | CCN1 | Cellular communication network factor 1. (381 aa) |
| | SIRT4 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa) |
| | APOC2 | Apolipoprotein C2. (101 aa) |
| | ABHD6 | Abhydrolase domain containing 6. (285 aa) |
| | SEC14L5 | SEC14 like lipid binding 5. (663 aa) |
| | APOB | Apolipoprotein B. (4555 aa) |
| | DHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa) |
| | LOC105507910 | FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa) |
| | LPIN1 | Lipin 1. (975 aa) |
| | LOC105501469 | GOLD domain-containing protein. (349 aa) |
| | CTDNEP1 | CTD nuclear envelope phosphatase 1. (244 aa) |
| | DHCR7 | 7-dehydrocholesterol reductase. (475 aa) |
| | LOC105513527 | FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | HTR2A | 5-hydroxytryptamine receptor 2A. (471 aa) |
| | ENSCANP00000001808 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (144 aa) |
| | ORMDL1 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) |
| | IDH1 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa) |
| | AVIL | Advillin. (819 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | ERLIN2 | ER lipid raft associated 2. (181 aa) |
| | CD74 | CD74 molecule. (294 aa) |
| | NR1H4 | Nuclear receptor subfamily 1 group H member 4. (486 aa) |
| | ABCA3 | ATP binding cassette subfamily A member 3. (1704 aa) |
| | ENSCANP00000003146 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (433 aa) |
| | SEC14L3 | Uncharacterized protein. (354 aa) |
| | SORBS1 | Sorbin and SH3 domain containing 1. (1294 aa) |
| | FABP5 | Fatty acid binding protein 5. (108 aa) |
| | NR1H3 | Nuclear receptor subfamily 1 group H member 3. (453 aa) |
| | LPCAT3 | Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (487 aa) |
| | RAB38 | RAB38, member RAS oncogene family. (211 aa) |
| | ABCA2 | ATP binding cassette subfamily A member 2. (2425 aa) |
| | LPCAT1 | Lysophosphatidylcholine acyltransferase 1. (381 aa) |
| | ENSCANP00000004157 | FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa) |
| | THRSP | Thyroid hormone responsive. (150 aa) |
| | MID1IP1 | MID1 interacting protein 1. (183 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) |
| | ENSCANP00000004465 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa) |
| | CCDC3 | Coiled-coil domain containing 3. (249 aa) |
| | MALRD1 | MAM and LDL receptor class A domain containing 1. (2080 aa) |
| | SCP2 | Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa) |
| | ENSCANP00000005400 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (101 aa) |
| | CYP7A1 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa) |
| | ENSCANP00000006139 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (101 aa) |
| | ADGRF5 | Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1343 aa) |
| | ASXL3 | ASXL transcriptional regulator 3. (2232 aa) |
| | CLCN2 | Chloride channel protein. (898 aa) |
| | APOA5 | Apolipoprotein A5. (366 aa) |
| | BMP5 | Bone morphogenetic protein 5. (454 aa) |
| | SIRT1 | Sirtuin 1. (600 aa) |
| | ORMDL3 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) |
| | LDLR | Low density lipoprotein receptor. (777 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (481 aa) |
| | DKK3 | Dickkopf WNT signaling pathway inhibitor 3. (331 aa) |
| | BMP6 | Bone morphogenetic protein 6. (331 aa) |
| | MLXIPL | MLX interacting protein like. (852 aa) |
| | FAM3A | Family with sequence similarity 3 member A. (244 aa) |
| | MFSD2A | Major facilitator superfamily domain containing 2A. (543 aa) |
| | ERLIN1 | ER lipid raft associated 1. (348 aa) |
| | PDK4 | Protein-serine/threonine kinase. (411 aa) |
| | AVPR1A | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa) |
| | LHCGR | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (699 aa) |
| | SLC27A1 | Solute carrier family 27 member 1. (626 aa) |
| | RDH10 | Retinol dehydrogenase 10. (176 aa) |
| | C3 | Complement C3. (1508 aa) |
| | INSIG1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa) |
| | SNAI2 | Snail family transcriptional repressor 2. (268 aa) |
| | TSPO | Uncharacterized protein. (65 aa) |
| | BMP2 | Bone morphogenetic protein 2. (396 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1335 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1331 aa) |
| | DAB2 | DAB adaptor protein 2. (770 aa) |
| | CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (509 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | SREBF1 | Sterol regulatory element binding transcription factor 1. (1148 aa) |
| | SOD1 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa) |
| | LOC105504501 | Uncharacterized protein. (210 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa) |
| | PLA2G3 | Phospholipase A2 group III. (509 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa) |
| | GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (841 aa) |
| | ABCD2 | ATP binding cassette subfamily D member 2. (722 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (220 aa) |
| | LOC105524144 | FCP1 homology domain-containing protein. (198 aa) |
| | TRIB3 | Tribbles pseudokinase 3. (385 aa) |
| | MBTPS1 | Membrane bound transcription factor peptidase, site 1. (1052 aa) |
| | DGAT2 | Diacylglycerol O-acyltransferase 2. (388 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) |
| | SEC14L2 | Uncharacterized protein. (403 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1775 aa) |
| | ACSL3 | Acyl-CoA synthetase long chain family member 3. (720 aa) |
| | SPHK2 | Sphingosine kinase 2. (658 aa) |
| | WDTC1 | WD and tetratricopeptide repeats 1. (687 aa) |
| | CREBL2 | cAMP responsive element binding protein like 2. (198 aa) |
| | DGKQ | Diacylglycerol kinase. (892 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | APOE | Apolipoprotein E. (189 aa) |
| | AKR1C3 | Aldo-keto reductase family 1 member C3. (323 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (173 aa) |
| | SERPINA12 | Serpin family A member 12; Belongs to the serpin family. (414 aa) |
| | SIRT3 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (350 aa) |
| | LOC105521701 | Aldo-keto reductase family 1 member C1. (323 aa) |
| | GIP | GLUCAGON domain-containing protein. (79 aa) |
| | GFI1 | Growth factor independent 1 transcriptional repressor. (422 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (802 aa) |
| | NR1H2 | Nuclear receptor subfamily 1 group H member 2. (459 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (335 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (614 aa) |
| | XBP1 | X-box binding protein 1. (204 aa) |
| | SPHK1 | Sphingosine kinase 1. (448 aa) |
| | ENSCANP00000024205 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa) |
| | GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (370 aa) |
| | EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa) |
| | PRMT3 | Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (531 aa) |
| | ORMDL2 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (970 aa) |
| | ADM | Adrenomedullin. (185 aa) |
| | ABCG1 | ATP binding cassette subfamily G member 1. (684 aa) |
| | NR0B1 | Nuclear receptor subfamily 0 group B member 1. (470 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (448 aa) |
| | LPGAT1 | Lysophosphatidylglycerol acyltransferase 1. (370 aa) |
| | ASAH1 | N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (411 aa) |
| | SNAI1 | Snail family transcriptional repressor 1. (264 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (345 aa) |
| | ABCD1 | ATP binding cassette subfamily D member 1. (745 aa) |
| | PIBF1 | Progesterone immunomodulatory binding factor 1. (757 aa) |
| | SREBF2 | Sterol regulatory element binding transcription factor 2. (1123 aa) |
| | SEC14L4 | SEC14 like lipid binding 4. (406 aa) |
| | CGA | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (150 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | CEACAM1 | Uncharacterized protein. (525 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | SLC45A3 | Solute carrier family 45 member 3. (553 aa) |
| | FITM2 | Fat storage inducing transmembrane protein 2. (262 aa) |
| | FBXW7 | F-box and WD repeat domain containing 7. (707 aa) |
| | SCARB1 | Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa) |
| | REST | RE1 silencing transcription factor. (1096 aa) |
| | H6PD | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (802 aa) |
| | PLA2G6 | Phospholipase A2 group VI. (806 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (527 aa) |
| | HSD17B13 | Hydroxysteroid 17-beta dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa) |
| | DDX20 | DEAD-box helicase 20. (825 aa) |
| | LOC105521702 | Aldo_ket_red domain-containing protein. (323 aa) |
| | POR | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (676 aa) |
| | ZBTB20 | Zinc finger and BTB domain containing 20. (741 aa) |
| | PLIN5 | Perilipin; Belongs to the perilipin family. (466 aa) |
| | SF1 | Splicing factor 1. (639 aa) |
| | CNEP1R1 | CTD nuclear envelope phosphatase 1 regulatory subunit 1. (123 aa) |
| | NR5A1 | Nuclear receptor subfamily 5 group A member 1. (461 aa) |
| | STAR | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa) |
| | SAMD8 | Sterile alpha motif domain containing 8. (443 aa) |
| | FABP3 | Fatty acid binding protein 3; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa) |
| | ENPP7 | Ectonucleotide pyrophosphatase/phosphodiesterase 7. (450 aa) |
| | STARD4 | StAR related lipid transfer domain containing 4. (205 aa) |
| | SCAP | SREBF chaperone. (1279 aa) |
| | ABCG4 | ATP binding cassette subfamily G member 4. (646 aa) |
| | DKKL1 | Dickkopf like acrosomal protein 1. (244 aa) |
| | ARMC5 | Armadillo repeat containing 5. (1031 aa) |
