STRINGSTRING
CCNB1 CCNB1 NDUFS4 NDUFS4 LIG4 LIG4 ENSCANP00000002034 ENSCANP00000002034 PLA2G1B PLA2G1B LIF LIF ZMIZ1 ZMIZ1 EREG EREG IGF1 IGF1 GAS6 GAS6 DHX9 DHX9 ENSCANP00000018729 ENSCANP00000018729 WNT2 WNT2 FBLN1 FBLN1 ENSCANP00000016772 ENSCANP00000016772 NGFR NGFR PDGFB PDGFB CDK4 CDK4 XRCC4 XRCC4 DDR2 DDR2 FOSL2 FOSL2 FN1 FN1 WNT1 WNT1 PDGFRB PDGFRB TGFB1 TGFB1 FGF10 FGF10 PML PML CTC1 CTC1 HRAS HRAS MIF MIF CD74 CD74 CD248 CD248 SIRT6 SIRT6 CDC6 CDC6 ENSCANP00000038603 ENSCANP00000038603 ENSCANP00000037159 ENSCANP00000037159 ESR1 ESR1 FNDC3B FNDC3B S100A6 S100A6 RNASEH2B RNASEH2B CDK6 CDK6 ENSCANP00000034830 ENSCANP00000034830 PDGFC PDGFC ABL1 ABL1 WNT5A WNT5A JUN JUN E2F1 E2F1 CCNA2 CCNA2 MYC MYC BRK1 BRK1 CDKN1A CDKN1A FBRS FBRS ITGB3 ITGB3 SPHK1 SPHK1 WAPL WAPL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCNB1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (345 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (174 aa)
LIG4DNA ligase. (911 aa)
ENSCANP00000002034Uncharacterized protein. (114 aa)
PLA2G1BPhospholipase A(2). (147 aa)
LIFLIF interleukin 6 family cytokine. (204 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1067 aa)
EREGEpiregulin. (169 aa)
IGF1Insulin like growth factor 1. (208 aa)
GAS6Growth arrest specific 6. (593 aa)
DHX9DExH-box helicase 9. (1275 aa)
ENSCANP00000018729Uncharacterized protein. (108 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (710 aa)
ENSCANP00000016772Uncharacterized protein. (67 aa)
NGFRNerve growth factor receptor. (427 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (220 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
XRCC4X-ray repair cross complementing 4. (336 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (855 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (309 aa)
FN1Fibronectin 1. (2450 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (336 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
PMLPromyelocytic leukemia. (882 aa)
CTC1CST telomere replication complex component 1. (1212 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
MIFUncharacterized protein. (114 aa)
CD74CD74 molecule. (294 aa)
CD248CD248 molecule. (757 aa)
SIRT6Sirtuin 6. (355 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (499 aa)
ENSCANP00000038603Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (409 aa)
ENSCANP00000037159Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (113 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
S100A6Protein S100; Belongs to the S-100 family. (90 aa)
RNASEH2BUncharacterized protein. (312 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
ENSCANP00000034830Ydr279_N domain-containing protein. (277 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (246 aa)
E2F1E2F transcription factor 1. (436 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
FBRSFibrosin. (841 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
SPHK1Sphingosine kinase 1. (448 aa)
WAPLWAPL cohesin release factor. (1190 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.