STRINGSTRING
WDR48 WDR48 ACVR2B ACVR2B NLE1 NLE1 CER1 CER1 PSEN1 PSEN1 RFLNA RFLNA SIX1 SIX1 RUNX2 RUNX2 HOXC4 HOXC4 SIX4 SIX4 HOXD10 HOXD10 COL3A1 COL3A1 DLX5 DLX5 RFLNB RFLNB CITED2 CITED2 ATG9B ATG9B SOX6 SOX6 NAB2 NAB2 MTHFD1L MTHFD1L WNT7A WNT7A FGFR2 FGFR2 THBS3 THBS3 HOXB2 HOXB2 NIPBL NIPBL MMP13 MMP13 HOXD3 HOXD3 RYK RYK SETD2 SETD2 LTF LTF NDST1 NDST1 SOX11 SOX11 SGPL1 SGPL1 TRIP11 TRIP11 PLEKHA1 PLEKHA1 EXT2 EXT2 EIF4A3 EIF4A3 MAPK14 MAPK14 BMP1 BMP1 P2RX7 P2RX7 SPEF2 SPEF2 EYA1 EYA1 TIPARP TIPARP RARA RARA TBX4 TBX4 GLI3 GLI3 RAB23 RAB23 MGP MGP CHSY1 CHSY1 WNT10B WNT10B BMP4 BMP4 SIX2 SIX2 TBXT TBXT PRRX1 PRRX1 SOX5 SOX5 SERPINH1 SERPINH1 IFITM5 IFITM5 HOXB3 HOXB3 MMP16 MMP16 SCUBE2 SCUBE2 STC1 STC1 FGR FGR FBN2 FBN2 TCF15 TCF15 INSIG1 INSIG1 ZEB1 ZEB1 COL13A1 COL13A1 TFAP2A TFAP2A HOXA1 HOXA1 FGF6 FGF6 CTNNB1 CTNNB1 RDH10 RDH10 COL11A2 COL11A2 WDR19 WDR19 GSC GSC FMN1 FMN1 BMPR1B BMPR1B INPPL1 INPPL1 TGFB1 TGFB1 PHOSPHO1 PHOSPHO1 FOXN3 FOXN3 COMP COMP FGF8 FGF8 IMPAD1 IMPAD1 GLG1 GLG1 HOXD8 HOXD8 MEF2C MEF2C HOXD9 HOXD9 HOXA11 HOXA11 HAS2 HAS2 ZMPSTE24 ZMPSTE24 HOXB8 HOXB8 THRA THRA BMP6 BMP6 HOXD4 HOXD4 DSPP DSPP HOXA5 HOXA5 DCANP1 DCANP1 PAX5 PAX5 SATB2 SATB2 ALPL ALPL ARID5B ARID5B ATG9A ATG9A TULP3 TULP3 PRKRA PRKRA PEX7 PEX7 RAB33B RAB33B COL1A1 COL1A1 HOXC11 HOXC11 HOXA3 HOXA3 MDFI MDFI FREM1 FREM1 HYAL2 HYAL2 CCN2 CCN2 BMP7 BMP7 ANKRD11 ANKRD11 HOXB4 HOXB4 EXT1 EXT1 ACTN3 ACTN3 MEF2D MEF2D RIPPLY2 RIPPLY2 PAPPA2 PAPPA2 CSRNP1 CSRNP1 ALX1 ALX1 HOXB6 HOXB6 SFRP1 SFRP1 PCGF2 PCGF2 SMAD3 SMAD3 MATN1 MATN1 HYAL1 HYAL1 MEGF8 MEGF8 AXIN2 AXIN2 HOXA2 HOXA2 WNT9B WNT9B HOXB9 HOXB9 TMEM119 TMEM119 IHH IHH MYF5 MYF5 NAB1 NAB1 LOC105517826 LOC105517826 ENSCANP00000003738 ENSCANP00000003738 NOG NOG CYP26B1 CYP26B1 HOXC9 HOXC9 TGFBR2 TGFBR2 TSKU TSKU TRPV4 TRPV4 ATF2 ATF2 TBX15 TBX15 DSCAML1 DSCAML1 IRX5 IRX5 TMEM107 TMEM107 RARG RARG OSR1 OSR1 LRP5 LRP5 ENSCANP00000038657 ENSCANP00000038657 FGF18 FGF18 MMP14 MMP14 OSR2 OSR2 ENSCANP00000038043 ENSCANP00000038043 BARX2 BARX2 ANXA6 ANXA6 WDR60 WDR60 HOXB7 HOXB7 SMAD2 SMAD2 LTBP3 LTBP3 FGFR1 FGFR1 PKD1 PKD1 ACAN ACAN FLVCR1 FLVCR1 SMPD3 SMPD3 ALX4 ALX4 DLX2 DLX2 HOXB1 HOXB1 IFT80 IFT80 DLG1 DLG1 DHRS3 DHRS3 ALX3 ALX3 SOX9 SOX9 NODAL NODAL ENSCANP00000033948 ENSCANP00000033948 COL11A1 COL11A1 FGFR3 FGFR3 ENSCANP00000033728 ENSCANP00000033728 ACP5 ACP5 NPPC NPPC MSX1 MSX1 ANKRD12 ANKRD12 NKX3-2 NKX3-2 BMPR2 BMPR2 TGFB3 TGFB3 LOC105506399 LOC105506399 MED12 MED12 SKI SKI HOXB5 HOXB5 ZFAND5 ZFAND5 SHOX2 SHOX2 COL27A1 COL27A1 ENSCANP00000030255 ENSCANP00000030255 CHST11 CHST11 HHIP HHIP OTOR OTOR SLC39A1 SLC39A1 TGFBR1 TGFBR1 SFRP4 SFRP4 CDX1 CDX1 GRHL2 GRHL2 NEUROG1 NEUROG1 TIFAB TIFAB LOC105500583 LOC105500583 HOXC8 HOXC8 ENSCANP00000028789 ENSCANP00000028789 COL2A1 COL2A1 WWOX WWOX PPARGC1B PPARGC1B FUZ FUZ PAX1 PAX1 IFT140 IFT140 RARB RARB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WDR48WD repeat domain 48. (677 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (750 aa)
NLE1Notchless homolog 1. (431 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (463 aa)
RFLNARefilin A. (216 aa)
SIX1SIX homeobox 1. (284 aa)
RUNX2RUNX family transcription factor 2. (475 aa)
HOXC4Homeobox C4. (264 aa)
SIX4SIX homeobox 4. (780 aa)
HOXD10Homeobox D10. (340 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
DLX5Distal-less homeobox 5. (289 aa)
RFLNBRefilin B. (144 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (898 aa)
SOX6SRY-box transcription factor 6. (828 aa)
NAB2NGFI-A binding protein 2. (525 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (896 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
FGFR2Fibroblast growth factor receptor. (838 aa)
THBS3Thrombospondin 3. (961 aa)
HOXB2Homeobox B2. (211 aa)
NIPBLNipped-B protein. (2804 aa)
MMP13Matrix metallopeptidase 13. (503 aa)
HOXD3Homeobox D3. (432 aa)
RYKReceptor like tyrosine kinase. (529 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2517 aa)
LTFLactotransferrin; Belongs to the transferrin family. (710 aa)
NDST1N-deacetylase and N-sulfotransferase 1. (882 aa)
SOX11Transcription factor SOX. (372 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
TRIP11Thyroid hormone receptor interactor 11. (1938 aa)
PLEKHA1Pleckstrin homology domain containing A1. (404 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (751 aa)
EIF4A3Eukaryotic translation initiation factor 4A3. (362 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
BMP1Metalloendopeptidase. (980 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
SPEF2Sperm flagellar 2. (2072 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
TIPARPTCDD inducible poly(ADP-ribose) polymerase. (657 aa)
RARARetinoic acid receptor alpha. (478 aa)
TBX4T-box transcription factor 4. (495 aa)
GLI3GLI family zinc finger 3. (1580 aa)
RAB23RAB23, member RAS oncogene family. (237 aa)
MGPMatrix Gla protein; Associates with the organic matrix of bone and cartilage. (128 aa)
CHSY1Hexosyltransferase. (716 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
SIX2SIX homeobox 2. (292 aa)
TBXTT-box transcription factor T. (435 aa)
PRRX1Paired related homeobox 1. (245 aa)
SOX5SRY-box transcription factor 5. (763 aa)
SERPINH1Serpin family H member 1; Belongs to the serpin family. (418 aa)
IFITM5Interferon induced transmembrane protein 5. (132 aa)
HOXB3Homeobox B3. (430 aa)
MMP16Matrix metallopeptidase 16. (607 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (954 aa)
STC1Stanniocalcin 1. (247 aa)
FGRTyrosine-protein kinase. (529 aa)
FBN2Fibrillin 2. (2912 aa)
TCF15Transcription factor 15. (164 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1124 aa)
COL13A1Collagen type XIII alpha 1 chain. (717 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
HOXA1Homeobox A1. (335 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
CTNNB1Catenin beta 1. (781 aa)
RDH10Retinol dehydrogenase 10. (176 aa)
COL11A2Collagen type XI alpha 2 chain. (1613 aa)
WDR19WD repeat domain 19. (1342 aa)
GSCGoosecoid homeobox. (145 aa)
FMN1Formin 1. (1415 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1258 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (336 aa)
PHOSPHO1Phosphoethanolamine/phosphocholine phosphatase. (267 aa)
FOXN3Forkhead box N3. (470 aa)
COMPCartilage oligomeric matrix protein. (757 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
IMPAD1Inositol monophosphatase domain containing 1. (359 aa)
GLG1Golgi glycoprotein 1. (1173 aa)
HOXD8Homeobox domain-containing protein. (106 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
HOXD9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (255 aa)
HOXA11Homeobox A11. (312 aa)
HAS2Hyaluronan synthase 2. (552 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (489 aa)
HOXB8Homeobox domain-containing protein. (243 aa)
THRAThyroid hormone receptor alpha. (593 aa)
BMP6Bone morphogenetic protein 6. (331 aa)
HOXD4Homeobox D4. (255 aa)
DSPPDentin sialophosphoprotein. (1113 aa)
HOXA5Homeobox A5. (270 aa)
DCANP1Dendritic cell associated nuclear protein. (214 aa)
PAX5Paired box 5. (391 aa)
SATB2DNA-binding protein SATB. (733 aa)
ALPLAlkaline phosphatase. (524 aa)
ARID5BAT-rich interaction domain 5B. (1156 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (852 aa)
TULP3TUB like protein 3; Belongs to the TUB family. (453 aa)
PRKRAProtein activator of interferon induced protein kinase EIF2AK2. (283 aa)
PEX7Peroxisomal biogenesis factor 7. (286 aa)
RAB33BRAB33B, member RAS oncogene family. (229 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
HOXC11Homeobox C11. (304 aa)
HOXA3Homeobox A3. (443 aa)
MDFIMyoD family inhibitor. (246 aa)
FREM1FRAS1 related extracellular matrix 1. (2178 aa)
HYAL2Hyaluronidase. (473 aa)
CCN2Cellular communication network factor 2. (301 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
ANKRD11Ankyrin repeat domain 11. (2647 aa)
HOXB4Homeobox B4. (206 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (913 aa)
MEF2DMyocyte enhancer factor 2D. (521 aa)
RIPPLY2Ripply transcriptional repressor 2. (128 aa)
PAPPA2Pappalysin 2. (1793 aa)
CSRNP1Cysteine and serine rich nuclear protein 1. (591 aa)
ALX1ALX homeobox 1. (326 aa)
HOXB6Homeobox B6. (224 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
MATN1Matrilin 1. (496 aa)
HYAL1Hyaluronidase. (450 aa)
MEGF8Multiple EGF like domains 8. (2837 aa)
AXIN2Axin 2. (843 aa)
HOXA2Homeobox A2. (374 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
HOXB9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (250 aa)
TMEM119Transmembrane protein 119. (283 aa)
IHHIndian hedgehog signaling molecule. (373 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
NAB1NGFI-A binding protein 1. (487 aa)
LOC105517826SERPIN domain-containing protein; Belongs to the serpin family. (382 aa)
ENSCANP00000003738Uncharacterized protein. (247 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
HOXC9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (260 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
TSKUTsukushi, small leucine rich proteoglycan. (353 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
TBX15T-box transcription factor 15. (602 aa)
DSCAML1DS cell adhesion molecule like 1. (2009 aa)
IRX5Iroquois homeobox 5. (483 aa)
TMEM107Transmembrane protein 107. (146 aa)
RARGRetinoic acid receptor gamma. (461 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1611 aa)
ENSCANP00000038657Fork-head domain-containing protein. (200 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
OSR2Odd-skipped related transciption factor 2. (418 aa)
ENSCANP00000038043Uncharacterized protein. (107 aa)
BARX2BARX homeobox 2. (279 aa)
ANXA6Annexin. (683 aa)
WDR60WD repeat domain 60. (971 aa)
HOXB7Homeobox B7. (217 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1127 aa)
FGFR1Fibroblast growth factor receptor. (815 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4053 aa)
ACANAggrecan. (2167 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (555 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
ALX4ALX homeobox 4. (409 aa)
DLX2Distal-less homeobox 2. (328 aa)
HOXB1Homeobox B1. (304 aa)
IFT80Intraflagellar transport 80. (777 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa)
DHRS3Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
ALX3ALX homeobox 3. (311 aa)
SOX9SRY-box transcription factor 9. (509 aa)
NODALNodal growth differentiation factor. (347 aa)
ENSCANP00000033948Homeobox domain-containing protein. (141 aa)
COL11A1Collagen type XI alpha 1 chain. (1764 aa)
FGFR3Fibroblast growth factor receptor. (808 aa)
ENSCANP00000033728Fork-head domain-containing protein. (426 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (325 aa)
NPPCNatriuretic peptide C. (126 aa)
MSX1Msh homeobox 1. (199 aa)
ANKRD12Ankyrin repeat domain 12. (2059 aa)
NKX3-2NK3 homeobox 2. (284 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1030 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
LOC105506399Uncharacterized protein. (246 aa)
MED12Mediator complex subunit 12. (1988 aa)
SKISKI proto-oncogene. (649 aa)
HOXB5Homeobox B5. (269 aa)
ZFAND5Zinc finger AN1-type containing 5. (213 aa)
SHOX2Short stature homeobox 2. (221 aa)
COL27A1Collagen type XXVII alpha 1 chain. (1839 aa)
ENSCANP00000030255Fork-head domain-containing protein. (189 aa)
CHST11Carbohydrate sulfotransferase. (352 aa)
HHIPHedgehog interacting protein. (700 aa)
OTOROtoraplin. (128 aa)
SLC39A1Solute carrier family 39 member 1. (330 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
SFRP4Secreted frizzled related protein 4. (368 aa)
CDX1Caudal type homeobox 1. (265 aa)
GRHL2Grainyhead like transcription factor 2. (625 aa)
NEUROG1Neurogenin 1. (237 aa)
TIFABTIFA inhibitor. (162 aa)
LOC105500583Uncharacterized protein. (275 aa)
HOXC8Homeobox C8. (242 aa)
ENSCANP00000028789Homeobox domain-containing protein. (120 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
WWOXWW domain containing oxidoreductase. (414 aa)
PPARGC1BPPARG coactivator 1 beta. (1025 aa)
FUZFuzzy planar cell polarity protein. (418 aa)
PAX1Paired box 1. (433 aa)
IFT140Intraflagellar transport 140. (1470 aa)
RARBRetinoic acid receptor beta. (448 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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