STRINGSTRING
EFNA5 EFNA5 OTP OTP ROBO1 ROBO1 KHDC3L KHDC3L RUFY3 RUFY3 SS18L1 SS18L1 ASPA ASPA CRABP2 CRABP2 PRKCI PRKCI ADNP ADNP ENSCANP00000016330 ENSCANP00000016330 SYNJ1 SYNJ1 BDNF BDNF DICER1 DICER1 IL6ST IL6ST PLXNC1 PLXNC1 GLI3 GLI3 RNF112 RNF112 SNW1 SNW1 XRCC5 XRCC5 IFNG IFNG SOX8 SOX8 ENSCANP00000013830 ENSCANP00000013830 TP73 TP73 BMPR2 BMPR2 DHX36 DHX36 OLIG2 OLIG2 CX3CR1 CX3CR1 LRP2 LRP2 ANKRD27 ANKRD27 NUMB NUMB EPHA4 EPHA4 DIXDC1 DIXDC1 RHEB RHEB SMARCD3 SMARCD3 UFL1 UFL1 EEF2K EEF2K LOC105506260 LOC105506260 LYN LYN PLAG1 PLAG1 NRP1 NRP1 BRAF BRAF FZD3 FZD3 KIT KIT TRPV2 TRPV2 DBNL DBNL DSCAM DSCAM SEMA4D SEMA4D CXCL12 CXCL12 L1CAM L1CAM GFAP GFAP TGM2 TGM2 CUL7 CUL7 IL6 IL6 HAP1 HAP1 ANAPC2 ANAPC2 ACY3 ACY3 PLXND1 PLXND1 MAP3K13 MAP3K13 DRD2 DRD2 SOX11 SOX11 CLCF1 CLCF1 ENSCANP00000000338 ENSCANP00000000338 NEFL NEFL TRIM32 TRIM32 MEGF8 MEGF8 RAB21 RAB21 LIG4 LIG4 ENSCANP00000001858 ENSCANP00000001858 CDKL5 CDKL5 AMIGO3 AMIGO3 SEMA5A SEMA5A MAN2A1 MAN2A1 LIF LIF NKX6-1 NKX6-1 JADE2 JADE2 PLXNB1 PLXNB1 LOC105527037 LOC105527037 AMIGO1 AMIGO1 CDH4 CDH4 LOC105520582 LOC105520582 MAG MAG GRM5 GRM5 LIMK1 LIMK1 RASSF10 RASSF10 ZNF335 ZNF335 BAIAP2 BAIAP2 LOC105500769 LOC105500769 PTPRD PTPRD SMO SMO TIAM2 TIAM2 CDKL3 CDKL3 KRAS KRAS NTF3 NTF3 ENSCANP00000032066 ENSCANP00000032066 DISC1 DISC1 EPHB2 EPHB2 OBSL1 OBSL1 BCL11A BCL11A IL1B IL1B MAP1B MAP1B NR2E1 NR2E1 ITPKA ITPKA EGR2 EGR2 SHOX2 SHOX2 E2F1 E2F1 SEMA7A SEMA7A TRPC5 TRPC5 SHH SHH KALRN KALRN RND2 RND2 SERPINE2 SERPINE2 HDAC1 HDAC1 PTN PTN GOLGA4 GOLGA4 CTF1 CTF1 SLITRK1 SLITRK1 HIF1A HIF1A MME MME WNT3A WNT3A PAX6 PAX6 NOTCH1 NOTCH1 RGS14 RGS14 TNFRSF1B TNFRSF1B ZNF365 ZNF365 STK11 STK11 LPAR3 LPAR3 NTN1 NTN1 FAIM FAIM SRF SRF ENSCANP00000026638 ENSCANP00000026638 SOX10 SOX10 PARP6 PARP6 SHTN1 SHTN1 MDK MDK ASCL1 ASCL1 NKX2-2 NKX2-2 MACF1 MACF1 ENSCANP00000025320 ENSCANP00000025320 TWF2 TWF2 DCT DCT HDAC2 HDAC2 LOC105524786 LOC105524786 PPP1CC PPP1CC XRCC2 XRCC2 GPER1 GPER1 FBXW8 FBXW8 ROBO2 ROBO2 CAPRIN2 CAPRIN2 LOC105510766 LOC105510766 OCM2 OCM2 GJC2 GJC2 WDR62 WDR62 SRRT SRRT SPEN SPEN MTOR MTOR LOC105508648 LOC105508648 DBN1 DBN1 CYFIP1 CYFIP1 DMRTA2 DMRTA2 NPTN NPTN NUMBL NUMBL IL34 IL34 SLIT2 SLIT2 PLXNB3 PLXNB3 DAG1 DAG1 FBXO31 FBXO31 SLC7A5 SLC7A5 CAPRIN1 CAPRIN1 SPINT1 SPINT1 WNT2 WNT2 ASPM ASPM CAMK2B CAMK2B LRP8 LRP8 LAYN LAYN PLXNA4 PLXNA4 NGF NGF RELN RELN LOC105522005 LOC105522005 PRPF19 PRPF19 TGFB1 TGFB1 NTRK2 NTRK2 PLXNA1 PLXNA1 PTPRZ1 PTPRZ1 PLXNA3 PLXNA3 CUX2 CUX2 ENSCANP00000009565 ENSCANP00000009565 FN1 FN1 MAP6 MAP6 OPRM1 OPRM1 PLXNB2 PLXNB2 WNT3 WNT3 SHANK3 SHANK3 MECP2 MECP2 NIN NIN CX3CL1 CX3CL1 ZFYVE27 ZFYVE27 SS18L2 SS18L2 TENM4 TENM4 TIAM1 TIAM1 PLXNA2 PLXNA2 CTNNB1 CTNNB1 SERPINF1 SERPINF1 BIN1 BIN1 VEGFC VEGFC LOC105516286 LOC105516286 ELL3 ELL3 GSX2 GSX2 TTBK1 TTBK1 POU4F2 POU4F2 TSPO TSPO BMP2 BMP2 STK25 STK25 CHODL CHODL XRCC4 XRCC4 MAPT MAPT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
OTPOrthopedia homeobox. (325 aa)
ROBO1Roundabout guidance receptor 1. (1598 aa)
KHDC3LMOEP19 domain-containing protein. (217 aa)
RUFY3RUN and FYVE domain containing 3. (613 aa)
SS18L1SS18L1 subunit of BAF chromatin remodeling complex. (373 aa)
ASPAAspartoacylase. (313 aa)
CRABP2Cellular retinoic acid binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
ADNPActivity dependent neuroprotector homeobox. (1103 aa)
ENSCANP00000016330Uncharacterized protein. (433 aa)
SYNJ1Synaptojanin 1. (1614 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (312 aa)
DICER1Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1920 aa)
IL6STInterleukin 6 signal transducer. (860 aa)
PLXNC1Plexin C1. (1431 aa)
GLI3GLI family zinc finger 3. (1580 aa)
RNF112Ring finger protein 112. (639 aa)
SNW1SNW domain containing 1. (571 aa)
XRCC5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
SOX8SRY-box transcription factor 8. (384 aa)
ENSCANP00000013830Uncharacterized protein. (148 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (636 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1030 aa)
DHX36DEAH-box helicase 36. (1008 aa)
OLIG2Oligodendrocyte transcription factor 2. (192 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (387 aa)
LRP2LDL receptor related protein 2. (4655 aa)
ANKRD27Ankyrin repeat domain 27. (958 aa)
NUMBNUMB endocytic adaptor protein. (652 aa)
EPHA4EPH receptor A4. (986 aa)
DIXDC1DIX domain containing 1. (683 aa)
RHEBRas homolog, mTORC1 binding. (179 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (508 aa)
UFL1UFM1 specific ligase 1. (793 aa)
EEF2KEukaryotic elongation factor 2 kinase. (725 aa)
LOC105506260X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (658 aa)
LYNTyrosine-protein kinase. (512 aa)
PLAG1PLAG1 zinc finger. (500 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (747 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (764 aa)
DBNLDrebrin like. (438 aa)
DSCAMDS cell adhesion molecule. (2010 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
L1CAML1 cell adhesion molecule. (1257 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (519 aa)
TGM2Transglutaminase 2. (687 aa)
CUL7Cullin 7; Belongs to the cullin family. (1697 aa)
IL6Interleukin 6. (214 aa)
HAP1Huntingtin associated protein 1. (650 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (822 aa)
ACY3Aminoacylase 3. (299 aa)
PLXND1Plexin D1. (1736 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13. (700 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
SOX11Transcription factor SOX. (372 aa)
CLCF1Cardiotrophin like cytokine factor 1. (223 aa)
ENSCANP00000000338Uncharacterized protein. (157 aa)
NEFLNeurofilament light; Belongs to the intermediate filament family. (543 aa)
TRIM32Tripartite motif containing 32. (653 aa)
MEGF8Multiple EGF like domains 8. (2837 aa)
RAB21RAB21, member RAS oncogene family. (223 aa)
LIG4DNA ligase. (911 aa)
ENSCANP00000001858Uncharacterized protein. (151 aa)
CDKL5Cyclin dependent kinase like 5. (1028 aa)
AMIGO3Adhesion molecule with Ig like domain 3. (504 aa)
SEMA5ASemaphorin 5A. (1074 aa)
MAN2A1Alpha-mannosidase. (1144 aa)
LIFLIF interleukin 6 family cytokine. (204 aa)
NKX6-1NK6 homeobox 1. (366 aa)
JADE2Jade family PHD finger 2. (834 aa)
PLXNB1Plexin B1. (2135 aa)
LOC105527037Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (459 aa)
AMIGO1Adhesion molecule with Ig like domain 1. (493 aa)
CDH4Cadherin 4; Cadherins are calcium-dependent cell adhesion proteins. (897 aa)
LOC105520582Arm_2 domain-containing protein. (547 aa)
MAGMyelin associated glycoprotein. (626 aa)
GRM5Glutamate metabotropic receptor 5. (1212 aa)
LIMK1LIM domain kinase 1. (677 aa)
RASSF10Ras association domain family member 10. (506 aa)
ZNF335Zinc finger protein 335. (1143 aa)
BAIAP2BAI1 associated protein 2. (534 aa)
LOC105500769Protein BHLHb9. (547 aa)
PTPRDProtein tyrosine phosphatase receptor type D. (1912 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (768 aa)
TIAM2T cell lymphoma invasion and metastasis 2. (1725 aa)
CDKL3Cyclin dependent kinase like 3. (592 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (278 aa)
ENSCANP00000032066Uncharacterized protein. (215 aa)
DISC1DISC1 scaffold protein. (739 aa)
EPHB2EPH receptor B2. (1082 aa)
OBSL1Obscurin like 1. (1672 aa)
BCL11ABAF chromatin remodeling complex subunit BCL11A. (843 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
MAP1BMicrotubule associated protein 1B. (2465 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (419 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (298 aa)
EGR2Early growth response 2. (476 aa)
SHOX2Short stature homeobox 2. (221 aa)
E2F1E2F transcription factor 1. (436 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (668 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
SHHSonic hedgehog signaling molecule. (390 aa)
KALRNKalirin RhoGEF kinase. (2986 aa)
RND2Rho family GTPase 2. (227 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (409 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (476 aa)
PTNPleiotrophin. (172 aa)
GOLGA4Golgin A4. (2242 aa)
CTF1Uncharacterized protein. (202 aa)
SLITRK1SLIT and NTRK like family member 1. (696 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (827 aa)
MMEMembrane metalloendopeptidase. (750 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
PAX6Paired box 6. (478 aa)
NOTCH1Notch receptor 1. (2559 aa)
RGS14Regulator of G protein signaling 14. (565 aa)
TNFRSF1BTNF receptor superfamily member 1B. (445 aa)
ZNF365Zinc finger protein 365. (411 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (353 aa)
NTN1Netrin 1. (576 aa)
FAIMFas apoptotic inhibitory molecule. (213 aa)
SRFSerum response factor. (406 aa)
ENSCANP00000026638Uncharacterized protein. (117 aa)
SOX10SRY-box transcription factor 10. (466 aa)
PARP6Poly [ADP-ribose] polymerase. (630 aa)
SHTN1Shootin 1. (631 aa)
MDKUncharacterized protein. (164 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (231 aa)
NKX2-2NK2 homeobox 2. (273 aa)
MACF1Microtubule actin crosslinking factor 1. (7562 aa)
ENSCANP00000025320RUN domain-containing protein. (562 aa)
TWF2Twinfilin actin binding protein 2. (349 aa)
DCTDopachrome tautomerase. (536 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
LOC105524786Uncharacterized protein. (334 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa)
XRCC2X-ray repair cross complementing 2. (281 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (370 aa)
FBXW8F-box and WD repeat domain containing 8. (524 aa)
ROBO2Roundabout guidance receptor 2. (1439 aa)
CAPRIN2Caprin family member 2. (1068 aa)
LOC105510766MOEP19 domain-containing protein. (217 aa)
OCM2Uncharacterized protein; Belongs to the parvalbumin family. (109 aa)
GJC2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (246 aa)
WDR62WD repeat domain 62. (1522 aa)
SRRTSerrate, RNA effector molecule. (872 aa)
SPENSpen family transcriptional repressor. (3641 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
LOC105508648Uncharacterized protein. (352 aa)
DBN1Drebrin 1. (688 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1234 aa)
DMRTA2DMRT like family A2. (309 aa)
NPTNNeuroplastin. (398 aa)
NUMBLNUMB like endocytic adaptor protein. (551 aa)
IL34Interleukin 34. (242 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
PLXNB3Plexin B3. (1913 aa)
DAG1Dystroglycan 1. (894 aa)
FBXO31F-box protein 31. (482 aa)
SLC7A5Solute carrier family 7 member 5. (474 aa)
CAPRIN1Cell cycle associated protein 1. (717 aa)
SPINT1Serine peptidase inhibitor, Kunitz type 1. (531 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
ASPMAbnormal spindle microtubule assembly. (3477 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
LRP8LDL receptor related protein 8. (880 aa)
LAYNLayilin. (382 aa)
PLXNA4Plexin A4. (1894 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (123 aa)
RELNReelin. (3299 aa)
LOC105522005Uncharacterized protein. (138 aa)
PRPF19Pre-mRNA processing factor 19. (412 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (336 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
PLXNA1Plexin A1. (1906 aa)
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (2319 aa)
PLXNA3Plexin A3. (1871 aa)
CUX2Homeobox protein cut-like. (1341 aa)
ENSCANP00000009565Uncharacterized protein. (651 aa)
FN1Fibronectin 1. (2450 aa)
MAP6Microtubule associated protein 6. (451 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
PLXNB2Plexin_cytopl domain-containing protein. (630 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1426 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
NINNinein. (2134 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (402 aa)
ZFYVE27Zinc finger FYVE-type containing 27. (416 aa)
SS18L2SS18 like 2. (77 aa)
TENM4Teneurin transmembrane protein 4. (2769 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1591 aa)
PLXNA2Plexin A2. (1909 aa)
CTNNB1Catenin beta 1. (781 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (366 aa)
BIN1Bridging integrator 1. (593 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (459 aa)
LOC105516286Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (449 aa)
ELL3Elongation factor for RNA polymerase II 3. (398 aa)
GSX2GS homeobox 2. (304 aa)
TTBK1Tau tubulin kinase 1. (1235 aa)
POU4F2POU domain protein. (407 aa)
TSPOUncharacterized protein. (65 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
STK25Serine/threonine kinase 25. (416 aa)
CHODLChondrolectin. (266 aa)
XRCC4X-ray repair cross complementing 4. (336 aa)
MAPTMicrotubule-associated protein. (685 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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