STRINGSTRING
HABP4 HABP4 ENSCANP00000000051 ENSCANP00000000051 LEF1 LEF1 ENSCANP00000000656 ENSCANP00000000656 LOC105503376 LOC105503376 WFIKKN1 WFIKKN1 HEY1 HEY1 MAD2L2 MAD2L2 LIF LIF CALM1 CALM1 ENSCANP00000003080 ENSCANP00000003080 NEUROD1 NEUROD1 CEBPG CEBPG EDF1 EDF1 PRKN PRKN ENSCANP00000005529 ENSCANP00000005529 SMO SMO ZMPSTE24 ZMPSTE24 KLF4 KLF4 GZMA GZMA NFKBIA NFKBIA MMP8 MMP8 TGFB1 TGFB1 ENSCANP00000009406 ENSCANP00000009406 GATA1 GATA1 DDRGK1 DDRGK1 ENSCANP00000009841 ENSCANP00000009841 CDT1 CDT1 LAMTOR5 LAMTOR5 HIPK2 HIPK2 ZNF593 ZNF593 LOC105517597 LOC105517597 ENSCANP00000011556 ENSCANP00000011556 ERCC4 ERCC4 CTNNB1 CTNNB1 POU4F2 POU4F2 ZNF462 ZNF462 ENSCANP00000013994 ENSCANP00000013994 WFIKKN2 WFIKKN2 EP300 EP300 IFNG IFNG CALM3 CALM3 NEK2 NEK2 LOC105527581 LOC105527581 SUMO1 SUMO1 HMGA2 HMGA2 SRI SRI ACD ACD ILRUN ILRUN ZNF675 ZNF675 TRAF6 TRAF6 FBXW9 FBXW9 MAPK10 MAPK10 EGF EGF TAF1 TAF1 ZC4H2 ZC4H2 TFAP4 TFAP4 ANKRD33B ANKRD33B IGF1 IGF1 DDIT3 DDIT3 MAPK8 MAPK8 RNF220 RNF220 TAF10 TAF10 HEY2 HEY2 ENSCANP00000021569 ENSCANP00000021569 SIN3A SIN3A DOT1L DOT1L IRF4 IRF4 PYHIN1 PYHIN1 MDFI MDFI IFI16 IFI16 LOC105501334 LOC105501334 GATA3 GATA3 ZBTB7C ZBTB7C CALM2 CALM2 HDAC2 HDAC2 AGER AGER SIRT2 SIRT2 PSEN1 PSEN1 HAND1 HAND1 HAND2 HAND2 MYOCD MYOCD PAX6 PAX6 TXN TXN ENSCANP00000028447 ENSCANP00000028447 NSD1 NSD1 CTNNBIP1 CTNNBIP1 E2F1 E2F1 ANKRD33 ANKRD33 ENSCANP00000031429 ENSCANP00000031429 JUN JUN SKI SKI PER2 PER2 SP100 SP100 ENSCANP00000032721 ENSCANP00000032721 HJURP HJURP MSX1 MSX1 ZFP90 ZFP90 NIBAN2 NIBAN2 FBXW7 FBXW7 NFIB NFIB MMP9 MMP9 JAK2 JAK2 REST REST ERCC2 ERCC2 PARP1 PARP1 RSF1 RSF1 TNKS TNKS PINX1 PINX1 POU4F1 POU4F1 ID1 ID1 LHX2 LHX2 PARK7 PARK7 ITGA2 ITGA2 ISL1 ISL1 TRIM28 TRIM28 BCL3 BCL3 ENSCANP00000038657 ENSCANP00000038657 ENSCANP00000038703 ENSCANP00000038703 SOX11 SOX11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HABP4Hyaluronan binding protein 4. (371 aa)
ENSCANP00000000051Ubiquitin-like domain-containing protein. (62 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
ENSCANP00000000656Uncharacterized protein. (178 aa)
LOC105503376Thioredoxin domain-containing protein. (104 aa)
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (548 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (308 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (210 aa)
LIFLIF interleukin 6 family cytokine. (204 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
ENSCANP00000003080NDK domain-containing protein; Belongs to the NDK family. (123 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
CEBPGCCAAT enhancer binding protein gamma. (150 aa)
EDF1Endothelial differentiation related factor 1. (122 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
ENSCANP00000005529Uncharacterized protein. (134 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (768 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (489 aa)
KLF4Kruppel like factor 4. (479 aa)
GZMAGranzyme A; Belongs to the peptidase S1 family. (262 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
MMP8Matrix metallopeptidase 8. (467 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (336 aa)
ENSCANP00000009406Uncharacterized protein; Belongs to the calmodulin family. (163 aa)
GATA1GATA binding protein 1. (413 aa)
DDRGK1DDRGK domain containing 1. (314 aa)
ENSCANP00000009841NDK domain-containing protein. (96 aa)
CDT1Chromatin licensing and DNA replication factor 1. (470 aa)
LAMTOR5Uncharacterized protein. (169 aa)
HIPK2Homeodomain interacting protein kinase 2. (1197 aa)
ZNF593Zinc finger protein 593. (156 aa)
LOC105517597DJ-1_PfpI domain-containing protein. (201 aa)
ENSCANP00000011556Small ubiquitin-related modifier. (73 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
CTNNB1Catenin beta 1. (781 aa)
POU4F2POU domain protein. (407 aa)
ZNF462Zinc finger protein 462. (2508 aa)
ENSCANP00000013994Nucleoside diphosphate kinase. (177 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (576 aa)
EP300E1A binding protein p300. (2409 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
CALM3Calmodulin 3. (149 aa)
NEK2NIMA related kinase 2. (445 aa)
LOC105527581HTH cro/C1-type domain-containing protein. (141 aa)
SUMO1Small ubiquitin like modifier 1. (120 aa)
HMGA2High mobility group AT-hook 2. (147 aa)
SRIUncharacterized protein. (198 aa)
ACDACD shelterin complex subunit and telomerase recruitment factor. (485 aa)
ILRUNInflammation and lipid regulator with UBA-like and NBR1-like domains. (298 aa)
ZNF675Uncharacterized protein. (560 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
FBXW9F-box and WD repeat domain containing 9. (479 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
TAF1Transcription initiation factor TFIID subunit. (1926 aa)
ZC4H2Zinc finger C4H2-type containing. (224 aa)
TFAP4Transcription factor AP-4. (312 aa)
ANKRD33BAnkyrin repeat domain 33B. (481 aa)
IGF1Insulin like growth factor 1. (208 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
RNF220Ring finger protein 220. (566 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
ENSCANP00000021569Small ubiquitin-related modifier. (106 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
DOT1LHistone-lysine N-methyltransferase, H3 lysine-79 specific. (1572 aa)
IRF4Interferon regulatory factor 4. (450 aa)
PYHIN1Pyrin and HIN domain family member 1. (492 aa)
MDFIMyoD family inhibitor. (246 aa)
IFI16Interferon gamma inducible protein 16. (729 aa)
LOC105501334Thioredoxin; Belongs to the thioredoxin family. (101 aa)
GATA3GATA binding protein 3. (444 aa)
ZBTB7CZinc finger and BTB domain containing 7C. (620 aa)
CALM2Calmodulin 2. (149 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
AGERAdvanced glycosylation end-product specific receptor. (403 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (388 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (463 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
HAND2Uncharacterized protein. (66 aa)
MYOCDMyocardin. (923 aa)
PAX6Paired box 6. (478 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
ENSCANP00000028447Uncharacterized protein; Belongs to the calmodulin family. (173 aa)
NSD1Nuclear receptor binding SET domain protein 1. (2682 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
E2F1E2F transcription factor 1. (436 aa)
ANKRD33Ankyrin repeat domain 33. (450 aa)
ENSCANP00000031429DJ-1_PfpI domain-containing protein. (124 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (246 aa)
SKISKI proto-oncogene. (649 aa)
PER2Period circadian regulator 2. (1254 aa)
SP100SP100 nuclear antigen. (819 aa)
ENSCANP00000032721Uncharacterized protein. (89 aa)
HJURPHolliday junction recognition protein. (721 aa)
MSX1Msh homeobox 1. (199 aa)
ZFP90ZFP90 zinc finger protein. (651 aa)
NIBAN2Niban apoptosis regulator 2. (746 aa)
FBXW7F-box and WD repeat domain containing 7. (707 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
MMP9Matrix metallopeptidase 9. (707 aa)
JAK2Tyrosine-protein kinase. (1139 aa)
RESTRE1 silencing transcription factor. (1096 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
RSF1Remodeling and spacing factor 1. (1422 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
PINX1PIN2 (TERF1) interacting telomerase inhibitor 1. (331 aa)
POU4F1POU domain protein. (288 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (154 aa)
LHX2LIM homeobox 2. (406 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
ISL1ISL LIM homeobox 1. (349 aa)
TRIM28Tripartite motif containing 28. (823 aa)
BCL3BCL3 transcription coactivator. (381 aa)
ENSCANP00000038657Fork-head domain-containing protein. (200 aa)
ENSCANP00000038703Uncharacterized protein. (89 aa)
SOX11Transcription factor SOX. (372 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.