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PLPP7 PLPP7 EREG EREG HEY2 HEY2 XBP1 XBP1 YBX1 YBX1 RGS2 RGS2 PPARA PPARA CTDP1 CTDP1 DLL1 DLL1 MYOCD MYOCD G6PD G6PD NOTCH1 NOTCH1 FZD7 FZD7 CCN3 CCN3 BHLHA15 BHLHA15 SMAD4 SMAD4 SHH SHH PTBP1 PTBP1 RBPMS2 RBPMS2 CCDC142 CCDC142 BMPR2 BMPR2 MSX1 MSX1 ENSCANP00000033979 ENSCANP00000033979 LOC105517265 LOC105517265 ENSCANP00000017238 ENSCANP00000017238 PDGFB PDGFB ANKRD17 ANKRD17 BMPR1A BMPR1A BMP2 BMP2 MED28 MED28 PI16 PI16 MECP2 MECP2 NFATC1 NFATC1 NFATC3 NFATC3 PDCD4 PDCD4 FOXP1 FOXP1 ENSCANP00000008732 ENSCANP00000008732 NFATC2 NFATC2 DKK1 DKK1 NKX2-5 NKX2-5 IGF2 IGF2 TCF23 TCF23 FOXO4 FOXO4 TRIM72 TRIM72 CAV3 CAV3 TMEM119 TMEM119 ENSCANP00000001411 ENSCANP00000001411 BHLHE41 BHLHE41 PRDM6 PRDM6 TOMM70 TOMM70 FRS2 FRS2 ENSCANP00000037455 ENSCANP00000037455 HDAC4 HDAC4 EZH2 EZH2 SMAD1 SMAD1 FGF9 FGF9 ENSCANP00000019087 ENSCANP00000019087 DNMT1 DNMT1 SOX6 SOX6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLPP7Phospholipid phosphatase 7 (inactive). (271 aa)
EREGEpiregulin. (169 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
XBP1X-box binding protein 1. (204 aa)
YBX1CSD_1 domain-containing protein. (275 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
PPARAPeroxisome proliferator activated receptor alpha. (448 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (859 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
MYOCDMyocardin. (923 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (546 aa)
NOTCH1Notch receptor 1. (2559 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (557 aa)
CCN3Cellular communication network factor 3. (357 aa)
BHLHA15Basic helix-loop-helix family member a15. (194 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
SHHSonic hedgehog signaling molecule. (390 aa)
PTBP1Polypyrimidine tract binding protein 1. (587 aa)
RBPMS2Uncharacterized protein. (94 aa)
CCDC142Coiled-coil domain containing 142. (750 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1030 aa)
MSX1Msh homeobox 1. (199 aa)
ENSCANP00000033979Uncharacterized protein. (185 aa)
LOC105517265RRM domain-containing protein. (457 aa)
ENSCANP00000017238CSD_1 domain-containing protein. (323 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (220 aa)
ANKRD17Ankyrin repeat domain 17. (2555 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
MED28Mediator complex subunit 28. (120 aa)
PI16Peptidase inhibitor 16; Belongs to the CRISP family. (466 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
NFATC1Nuclear factor of activated T cells 1. (815 aa)
NFATC3Nuclear factor of activated T cells 3. (1067 aa)
PDCD4Programmed cell death 4. (470 aa)
FOXP1Forkhead box P1. (693 aa)
ENSCANP00000008732CSP domain-containing protein. (296 aa)
NFATC2Nuclear factor of activated T cells 2. (923 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
NKX2-5NK2 homeobox 5. (324 aa)
IGF2Insulin like growth factor 2. (236 aa)
TCF23Transcription factor 23. (214 aa)
FOXO4Forkhead box O4. (505 aa)
TRIM72Tripartite motif containing 72. (267 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
TMEM119Transmembrane protein 119. (283 aa)
ENSCANP00000001411Uncharacterized protein. (196 aa)
BHLHE41Basic helix-loop-helix family member e41. (287 aa)
PRDM6PR/SET domain 6. (498 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (608 aa)
FRS2Fibroblast growth factor receptor substrate 2. (521 aa)
ENSCANP00000037455Uncharacterized protein. (303 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1090 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ENSCANP00000019087Uncharacterized protein. (298 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1646 aa)
SOX6SRY-box transcription factor 6. (828 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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