STRINGSTRING
SHOX2 SHOX2 MAPK14 MAPK14 MMP14 MMP14 HOPX HOPX KIT KIT ENSCANP00000033724 ENSCANP00000033724 MYOD1 MYOD1 TARBP2 TARBP2 NIBAN2 NIBAN2 EFEMP2 EFEMP2 SHH SHH PROX1 PROX1 OLFM2 OLFM2 BMP10 BMP10 WNT3A WNT3A NRG1 NRG1 SMYD1 SMYD1 MYOCD MYOCD SETD3 SETD3 ACTN3 ACTN3 LMOD3 LMOD3 GPER1 GPER1 ATP11A ATP11A EFNB2 EFNB2 MTOR MTOR LAMA2 LAMA2 AKAP6 AKAP6 IGF1 IGF1 MYOG MYOG MAML1 MAML1 BMP4 BMP4 RBM24 RBM24 MAPK12 MAPK12 PIEZO1 PIEZO1 KAT2A KAT2A LAMA1 LAMA1 TGFB1 TGFB1 SIRT1 SIRT1 MYF6 MYF6 SOD2 SOD2 MEF2C MEF2C RBM4B RBM4B NID1 NID1 MAMSTR MAMSTR BCL2 BCL2 LAMB2 LAMB2 CYP26B1 CYP26B1 ENSCANP00000003738 ENSCANP00000003738 MYF5 MYF5 CAV3 CAV3 ENG ENG MAPK11 MAPK11 PARP2 PARP2 TRIM32 TRIM32 EDN1 EDN1 CAMK1 CAMK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SHOX2Short stature homeobox 2. (221 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
HOPXHOP homeobox. (112 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
ENSCANP00000033724Uncharacterized protein. (794 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
TARBP2RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] (366 aa)
NIBAN2Niban apoptosis regulator 2. (746 aa)
EFEMP2EGF containing fibulin extracellular matrix protein 2. (443 aa)
SHHSonic hedgehog signaling molecule. (390 aa)
PROX1Prospero homeobox 1. (737 aa)
OLFM2Olfactomedin 2. (454 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
NRG1Neuregulin 1. (645 aa)
SMYD1SET and MYND domain containing 1. (497 aa)
MYOCDMyocardin. (923 aa)
SETD3Protein-histidine N-methyltransferase. (595 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (913 aa)
LMOD3Leiomodin 3. (559 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (370 aa)
ATP11APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1183 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (335 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
LAMA2Laminin subunit alpha 2. (3066 aa)
AKAP6A-kinase anchoring protein 6. (2319 aa)
IGF1Insulin like growth factor 1. (208 aa)
MYOGMyogenin. (249 aa)
MAML1Mastermind like transcriptional coactivator 1. (924 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
RBM24RNA binding motif protein 24. (252 aa)
MAPK12Mitogen-activated protein kinase. (325 aa)
PIEZO1Piezo-type mechanosensitive ion channel component. (2502 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
LAMA1Laminin subunit alpha 1. (3054 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (336 aa)
SIRT1Sirtuin 1. (600 aa)
MYF6Myogenic factor 6. (242 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (236 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
RBM4BRNA binding motif protein 4B. (359 aa)
NID1Nidogen 1. (1247 aa)
MAMSTRMEF2 activating motif and SAP domain containing transcriptional regulator. (415 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
LAMB2Laminin subunit beta 2. (1798 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
ENSCANP00000003738Uncharacterized protein. (247 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
ENGEndoglin. (658 aa)
MAPK11Mitogen-activated protein kinase. (306 aa)
PARP2Poly [ADP-ribose] polymerase. (494 aa)
TRIM32Tripartite motif containing 32. (653 aa)
EDN1Endothelin 1. (211 aa)
CAMK1Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (370 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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