STRINGSTRING
GPS1 GPS1 MAP4K2 MAP4K2 MAP3K7 MAP3K7 ATF2 ATF2 ENSCANP00000004223 ENSCANP00000004223 ZFP36 ZFP36 SMAD3 SMAD3 CARD9 CARD9 MAP2K7 MAP2K7 TLR7 TLR7 MAPK11 MAPK11 PBK PBK MAP2K4 MAP2K4 CCM2 CCM2 MAPK8IP2 MAPK8IP2 NFKB1 NFKB1 MAP3K5 MAP3K5 MAPK1 MAPK1 SH2D3C SH2D3C ARHGEF6 ARHGEF6 ERCC6 ERCC6 DUSP9 DUSP9 FGF14 FGF14 WNT5A WNT5A LRRK2 LRRK2 MAPK13 MAPK13 MAPKAPK2 MAPKAPK2 STRADB STRADB MAP3K11 MAP3K11 IRAK1 IRAK1 TRIB1 TRIB1 MINK1 MINK1 MAPK10 MAPK10 TNFRSF19 TNFRSF19 MAP4K3 MAP4K3 MAP2K3 MAP2K3 MAP3K20 MAP3K20 ZFP36L1 ZFP36L1 MAPK3 MAPK3 TNFSF11 TNFSF11 IKBKB IKBKB MAPK9 MAPK9 TLR3 TLR3 TAOK2 TAOK2 MAP4K1 MAP4K1 MAP3K12 MAP3K12 SH2D3A SH2D3A MAPK14 MAPK14 DUSP10 DUSP10 MAP3K13 MAP3K13 MAP3K10 MAP3K10 CASR CASR GPS2 GPS2 MYD88 MYD88 CRKL CRKL IRAK4 IRAK4 NOD2 NOD2 MAPK8IP1 MAPK8IP1 TLR4 TLR4 DAXX DAXX MAPK8 MAPK8 RIPK2 RIPK2 FGF12 FGF12 NPHS1 NPHS1 NOD1 NOD1 MAP2K6 MAP2K6 ENSCANP00000006830 ENSCANP00000006830 STK3 STK3 NOX1 NOX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GPS1G protein pathway suppressor 1. (536 aa)
MAP4K2Mitogen-activated protein kinase kinase kinase kinase 2; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (797 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
ENSCANP00000004223Protein kinase domain-containing protein. (379 aa)
ZFP36ZFP36 ring finger protein. (332 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
CARD9Caspase recruitment domain family member 9. (536 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (468 aa)
TLR7Toll like receptor 7; Belongs to the Toll-like receptor family. (1049 aa)
MAPK11Mitogen-activated protein kinase. (306 aa)
PBKPDZ binding kinase. (335 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (373 aa)
CCM2CCM2 scaffold protein. (466 aa)
MAPK8IP2PID domain-containing protein. (178 aa)
NFKB1Nuclear factor kappa B subunit 1. (970 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1364 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
SH2D3CSH2 domain containing 3C. (860 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (776 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1494 aa)
DUSP9Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (385 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
MAPK13Mitogen-activated protein kinase. (491 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (431 aa)
STRADBSTE20 related adaptor beta. (377 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (847 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (648 aa)
TRIB1Tribbles pseudokinase 1. (206 aa)
MINK1Misshapen like kinase 1. (1363 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
TNFRSF19TNF receptor superfamily member 19. (429 aa)
MAP4K3Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (894 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (800 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (317 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
MAPK9Mitogen-activated protein kinase. (399 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa)
TAOK2TAO kinase 2. (1236 aa)
MAP4K1Mitogen-activated protein kinase kinase kinase kinase 1; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (834 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (890 aa)
SH2D3ASH2 domain containing 3A. (549 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
DUSP10Dual specificity phosphatase 10. (488 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13. (700 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase 10. (777 aa)
CASRCalcium sensing receptor. (1088 aa)
GPS2G protein pathway suppressor 2. (327 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (317 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (438 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
MAPK8IP1Mitogen-activated protein kinase 8 interacting protein 1. (614 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
DAXXDeath domain associated protein. (751 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1240 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
ENSCANP00000006830Protein kinase domain-containing protein. (373 aa)
STK3Serine/threonine kinase 3. (489 aa)
NOX1NADPH oxidase 1. (522 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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