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INSIG1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa) | ||||
ABCA1 | ATP binding cassette subfamily A member 1. (2264 aa) | ||||
LPL | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa) | ||||
LOC105504501 | Uncharacterized protein. (210 aa) | ||||
MTTP | Microsomal triglyceride transfer protein. (909 aa) | ||||
LCAT | Lecithin-cholesterol acyltransferase. (440 aa) | ||||
TLCD2 | TLC domain containing 2. (264 aa) | ||||
DDX3X | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (721 aa) | ||||
CETP | Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (493 aa) | ||||
EPHX2 | Epoxide hydrolase 2. (547 aa) | ||||
DGAT2 | Diacylglycerol O-acyltransferase 2. (388 aa) | ||||
RTN4 | Reticulon. (986 aa) | ||||
G6PC | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa) | ||||
USF1 | Upstream transcription factor 1. (310 aa) | ||||
NR1D2 | Nuclear receptor subfamily 1 group D member 2. (580 aa) | ||||
TLCD4 | TLC domain containing 4. (242 aa) | ||||
ABCA5 | ATP binding cassette subfamily A member 5. (1642 aa) | ||||
POLD1 | DNA polymerase delta 1, catalytic subunit. (1012 aa) | ||||
APOE | Apolipoprotein E. (189 aa) | ||||
COMMD9 | COMM domain containing 9. (198 aa) | ||||
NR5A2 | Nuclear receptor subfamily 5 group A member 2. (541 aa) | ||||
MYLIP | Myosin regulatory light chain interacting protein. (445 aa) | ||||
GCKR | Glucokinase regulator. (437 aa) | ||||
ADCK1 | AarF domain containing kinase 1. (523 aa) | ||||
GIP | GLUCAGON domain-containing protein. (79 aa) | ||||
LAMTOR1 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa) | ||||
CLN8 | CLN8 transmembrane ER and ERGIC protein. (286 aa) | ||||
DISP3 | Dispatched RND transporter family member 3. (1390 aa) | ||||
CD24 | Uncharacterized protein. (127 aa) | ||||
NFE2L1 | Nuclear factor, erythroid 2 like 1. (772 aa) | ||||
FABP3 | Fatty acid binding protein 3; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa) | ||||
SURF4 | Surfeit 4. (269 aa) | ||||
HDAC9 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa) | ||||
GRAMD1B | GRAM domain containing 1B. (877 aa) | ||||
SESN2 | Sestrin 2. (479 aa) | ||||
CYP39A1 | Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (469 aa) | ||||
ENSCANP00000028764 | Uncharacterized protein. (183 aa) | ||||
RALY | RALY heterogeneous nuclear ribonucleoprotein. (309 aa) | ||||
FUNDC2 | FUN14 domain containing 2. (189 aa) | ||||
SOAT1 | O-acyltransferase. (525 aa) | ||||
NPC1L1 | NPC1 like intracellular cholesterol transporter 1. (1326 aa) | ||||
TLCD1 | TLC domain containing 1. (247 aa) | ||||
PNPLA1 | Patatin like phospholipase domain containing 1. (532 aa) | ||||
RALYL | RALY RNA binding protein like. (304 aa) | ||||
FITM2 | Fat storage inducing transmembrane protein 2. (262 aa) | ||||
ACOX2 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (681 aa) | ||||
FBXW7 | F-box and WD repeat domain containing 7. (707 aa) | ||||
SCARB1 | Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa) | ||||
ENPP7 | Ectonucleotide pyrophosphatase/phosphodiesterase 7. (450 aa) | ||||
ABCG4 | ATP binding cassette subfamily G member 4. (646 aa) | ||||
PNPLA2 | Patatin like phospholipase domain containing 2. (428 aa) | ||||
LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1611 aa) | ||||
PLA2G12B | Phospholipase A2 group XIIB. (195 aa) | ||||
MTCH2 | Mitochondrial carrier 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (294 aa) | ||||
TTC39A | Tetratricopeptide repeat domain 39A. (612 aa) | ||||
RORA | RAR related orphan receptor A. (555 aa) | ||||
DGAT1 | O-acyltransferase. (470 aa) | ||||
APOC4 | Uncharacterized protein. (127 aa) | ||||
HNF4A | Hepatocyte nuclear factor 4 alpha. (464 aa) | ||||
MED13 | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2173 aa) | ||||
NPC1 | NPC intracellular cholesterol transporter 1. (1277 aa) | ||||
RCN3 | Reticulocalbin 3. (328 aa) | ||||
TLCD3A | TLC domain containing 3A. (216 aa) | ||||
LDLRAP1 | Low density lipoprotein receptor adaptor protein 1. (278 aa) | ||||
PCSK9 | Proprotein convertase subtilisin/kexin type 9. (692 aa) | ||||
ZBTB20 | Zinc finger and BTB domain containing 20. (741 aa) | ||||
SREBF2 | Sterol regulatory element binding transcription factor 2. (1123 aa) | ||||
CYP7B1 | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (505 aa) | ||||
ABCD1 | ATP binding cassette subfamily D member 1. (745 aa) | ||||
PRKAA2 | Non-specific serine/threonine protein kinase. (545 aa) | ||||
PLSCR3 | Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (312 aa) | ||||
PNPLA3 | Patatin like phospholipase domain containing 3. (418 aa) | ||||
TLCD3B | TLC domain containing 3B. (274 aa) | ||||
ABCA12 | ATP binding cassette subfamily A member 12. (2556 aa) | ||||
ENSCANP00000025349 | Uncharacterized protein. (100 aa) | ||||
OR10J5 | Olfactory receptor family 10 subfamily J member 5. (289 aa) | ||||
ABCG1 | ATP binding cassette subfamily G member 1. (684 aa) | ||||
ABCG5 | ATP binding cassette subfamily G member 5. (651 aa) | ||||
ORMDL2 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) | ||||
ACSM1 | Acyl-CoA synthetase medium chain family member 1. (462 aa) | ||||
ENSCANP00000024205 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa) | ||||
LIMA1 | LIM domain and actin binding 1. (753 aa) | ||||
XBP1 | X-box binding protein 1. (204 aa) | ||||
SLC25A46 | Solute carrier family 25 member 46; Belongs to the mitochondrial carrier (TC 2.A.29) family. (418 aa) | ||||
APOA2 | Apolipoprotein A2. (100 aa) | ||||
TTC39B | Tetratricopeptide repeat domain 39B. (682 aa) | ||||
ITGB6 | Integrin beta; Belongs to the integrin beta chain family. (746 aa) | ||||
LIPC | Lipase C, hepatic type. (499 aa) | ||||
GPIHBP1 | Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. (141 aa) | ||||
MLXIPL | MLX interacting protein like. (852 aa) | ||||
CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (179 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (336 aa) | ||||
LDLR | Low density lipoprotein receptor. (777 aa) | ||||
ABCG8 | ATP binding cassette subfamily G member 8. (620 aa) | ||||
NR1D1 | Nuclear receptor subfamily 1 group D member 1. (614 aa) | ||||
NR1H2 | Nuclear receptor subfamily 1 group H member 2. (459 aa) | ||||
LOC105502173 | RRM domain-containing protein. (250 aa) | ||||
PNPLA8 | Patatin like phospholipase domain containing 8. (782 aa) | ||||
LIPG | Lipase G, endothelial type. (500 aa) | ||||
ACACA | Acetyl-CoA carboxylase alpha. (2383 aa) | ||||
ORMDL3 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) | ||||
SIRT1 | Sirtuin 1. (600 aa) | ||||
GPAM | Glycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa) | ||||
THADA | THADA armadillo repeat containing. (1953 aa) | ||||
ATP13A2 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1106 aa) | ||||
APOA5 | Apolipoprotein A5. (366 aa) | ||||
NPC2 | NPC intracellular cholesterol transporter 2. (229 aa) | ||||
FGFR4 | Fibroblast growth factor receptor. (802 aa) | ||||
SEC24A | SEC24 homolog A, COPII coat complex component. (1078 aa) | ||||
CYP7A1 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa) | ||||
NUS1 | NUS1 dehydrodolichyl diphosphate synthase subunit. (293 aa) | ||||
MALRD1 | MAM and LDL receptor class A domain containing 1. (2080 aa) | ||||
TSKU | Tsukushi, small leucine rich proteoglycan. (353 aa) | ||||
ENSCANP00000004126 | Uncharacterized protein. (79 aa) | ||||
ABCA2 | ATP binding cassette subfamily A member 2. (2425 aa) | ||||
RBP1 | Retinol binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (197 aa) | ||||
NR1H3 | Nuclear receptor subfamily 1 group H member 3. (453 aa) | ||||
ABHD4 | Abhydrolase domain containing 4. (352 aa) | ||||
USF2 | Upstream transcription factor 2, c-fos interacting. (218 aa) | ||||
TREM2 | Triggering receptor expressed on myeloid cells 2. (230 aa) | ||||
ABCB11 | ATP binding cassette subfamily B member 11. (1321 aa) | ||||
PNPLA5 | Patatin like phospholipase domain containing 5. (429 aa) | ||||
C1QTNF3 | C1q domain-containing protein. (319 aa) | ||||
ANGPTL3 | Angiopoietin like 3. (460 aa) | ||||
ABCA3 | ATP binding cassette subfamily A member 3. (1704 aa) | ||||
NR1H4 | Nuclear receptor subfamily 1 group H member 4. (486 aa) | ||||
TLCD5 | TLC domain containing 5. (267 aa) | ||||
SLC37A4 | Solute carrier family 37 member 4. (451 aa) | ||||
TMEM97 | Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins. (176 aa) | ||||
FABP4 | Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa) | ||||
PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) | ||||
PNPLA4 | Patatin like phospholipase domain containing 4. (253 aa) | ||||
ABHD8 | Abhydrolase domain containing 8. (438 aa) | ||||
SOAT2 | O-acyltransferase. (460 aa) | ||||
MTLN | Mitoregulin. (118 aa) | ||||
TM6SF2 | Transmembrane 6 superfamily member 2. (345 aa) | ||||
TSPO | Uncharacterized protein. (65 aa) | ||||
CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa) | ||||
ANGPTL8 | Angiopoietin like 8. (198 aa) | ||||
LOC105507530 | Uncharacterized protein. (462 aa) | ||||
APOB | Apolipoprotein B. (4555 aa) | ||||
IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) | ||||
APOC2 | Apolipoprotein C2. (101 aa) |