STRINGSTRING
FGF8 FGF8 NKX3-1 NKX3-1 PTCH1 PTCH1 PLXNA2 PLXNA2 ACVR1 ACVR1 BMPR1A BMPR1A BMP4 BMP4 EYA1 EYA1 BMP7 BMP7 EDNRA EDNRA SIX4 SIX4 GATA3 GATA3 FOLR1 FOLR1 NOG NOG HOXA2 HOXA2 BMPR2 BMPR2 ISL1 ISL1 TGFBR1 TGFBR1 ECE1 ECE1 TGFB2 TGFB2 EDN1 EDN1 RIPPLY3 RIPPLY3 ADGRF5 ADGRF5 BMP5 BMP5 ENSCANP00000003738 ENSCANP00000003738 NKX2-5 NKX2-5 NKX2-6 NKX2-6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
NKX3-1NK3 homeobox 1. (232 aa)
PTCH1Patched 1. (1449 aa)
PLXNA2Plexin A2. (1909 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
SIX4SIX homeobox 4. (780 aa)
GATA3GATA binding protein 3. (444 aa)
FOLR1Folate receptor alpha. (257 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
HOXA2Homeobox A2. (374 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1030 aa)
ISL1ISL LIM homeobox 1. (349 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
ECE1Endothelin converting enzyme 1. (768 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
EDN1Endothelin 1. (211 aa)
RIPPLY3Ripply transcriptional repressor 3. (150 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1343 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
ENSCANP00000003738Uncharacterized protein. (247 aa)
NKX2-5NK2 homeobox 5. (324 aa)
NKX2-6NK2 homeobox 6. (301 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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