STRINGSTRING
NOTCH1 NOTCH1 NRG1 NRG1 ADGRG6 ADGRG6 BMP10 BMP10 TGFBR1 TGFBR1 HEY2 HEY2 BMP7 BMP7 MED1 MED1 HEY1 HEY1 S1PR1 S1PR1 ENG ENG CAV3 CAV3 NOG NOG FHL2 FHL2 BMP5 BMP5 NKX2-5 NKX2-5 DLL4 DLL4 BMPR1A BMPR1A HEG1 HEG1 FOXH1 FOXH1 TGFBR3 TGFBR3 CHD7 CHD7 LOC105523238 LOC105523238 ADAMTS1 ADAMTS1 EGLN1 EGLN1 SOS1 SOS1 OVOL2 OVOL2 TGFB2 TGFB2 LOC105522577 LOC105522577 SRF SRF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NOTCH1Notch receptor 1. (2559 aa)
NRG1Neuregulin 1. (645 aa)
ADGRG6Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family. (1249 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1576 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (308 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
ENGEndoglin. (658 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
FHL2Four and a half LIM domains 2. (363 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
NKX2-5NK2 homeobox 5. (324 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
HEG1Heart development protein with EGF like domains 1. (1274 aa)
FOXH1Forkhead box H1. (366 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2998 aa)
LOC105523238Uncharacterized protein. (681 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (967 aa)
EGLN1Fe2OG dioxygenase domain-containing protein. (128 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1310 aa)
OVOL2Ovo like zinc finger 2. (252 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
LOC105522577Uncharacterized protein. (399 aa)
SRFSerum response factor. (406 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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