24 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SMURF1	E3 ubiquitin-protein ligase. (763 aa)
	LDLRAD4	Low density lipoprotein receptor class A domain containing 4. (306 aa)
	DDX5	DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
	JUN	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (246 aa)
	TRIM33	Tripartite motif containing 33. (1046 aa)
	PARP1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	ANKRD1	Ankyrin repeat domain 1. (319 aa)
	ENSCANP00000003939	PPM-type phosphatase domain-containing protein. (346 aa)
	MEN1	Menin 1. (610 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	PPM1A	Protein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
	RANBP3	RAN binding protein 3. (569 aa)
	FOXH1	Forkhead box H1. (366 aa)
	ENSCANP00000012853	C2 domain-containing protein. (51 aa)
	PMEPA1	Prostate transmembrane protein, androgen induced 1. (259 aa)
	ZC3H3	Zinc finger CCCH-type containing 3. (948 aa)
	RGCC	Regulator of cell cycle. (208 aa)
	FOS	Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
	AXIN1	Axin 1. (859 aa)
	DROSHA	Drosha ribonuclease III. (1369 aa)
	MYOCD	Myocardin. (923 aa)
	PAX6	Paired box 6. (478 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN1	ENSCANP00000012853	ENSCANP00000022666	ENSCANP00000012853	Axin 1.	C2 domain-containing protein.	0.600
AXIN1	SMAD3	ENSCANP00000022666	ENSCANP00000000895	Axin 1.	Mothers against decapentaplegic homolog.	0.410
AXIN1	SMURF1	ENSCANP00000022666	ENSCANP00000029030	Axin 1.	E3 ubiquitin-protein ligase.	0.604
DDX5	DROSHA	ENSCANP00000029768	ENSCANP00000023828	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Drosha ribonuclease III.	0.973
DDX5	FOS	ENSCANP00000029768	ENSCANP00000019070	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.434
DDX5	LDLRAD4	ENSCANP00000029768	ENSCANP00000029405	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Low density lipoprotein receptor class A domain containing 4.	0.471
DDX5	PMEPA1	ENSCANP00000029768	ENSCANP00000016628	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Prostate transmembrane protein, androgen induced 1.	0.471
DDX5	SMAD2	ENSCANP00000029768	ENSCANP00000036850	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Mothers against decapentaplegic homolog.	0.427
DDX5	SMAD3	ENSCANP00000029768	ENSCANP00000000895	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Mothers against decapentaplegic homolog.	0.604
DROSHA	DDX5	ENSCANP00000023828	ENSCANP00000029768	Drosha ribonuclease III.	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	0.973
DROSHA	SMAD2	ENSCANP00000023828	ENSCANP00000036850	Drosha ribonuclease III.	Mothers against decapentaplegic homolog.	0.676
DROSHA	SMAD3	ENSCANP00000023828	ENSCANP00000000895	Drosha ribonuclease III.	Mothers against decapentaplegic homolog.	0.547
DROSHA	SMAD4	ENSCANP00000023828	ENSCANP00000029295	Drosha ribonuclease III.	Mothers against decapentaplegic homolog.	0.422
ENSCANP00000003939	SMAD2	ENSCANP00000003939	ENSCANP00000036850	PPM-type phosphatase domain-containing protein.	Mothers against decapentaplegic homolog.	0.618
ENSCANP00000003939	SMAD3	ENSCANP00000003939	ENSCANP00000000895	PPM-type phosphatase domain-containing protein.	Mothers against decapentaplegic homolog.	0.582
ENSCANP00000003939	SMAD4	ENSCANP00000003939	ENSCANP00000029295	PPM-type phosphatase domain-containing protein.	Mothers against decapentaplegic homolog.	0.595
ENSCANP00000012853	AXIN1	ENSCANP00000012853	ENSCANP00000022666	C2 domain-containing protein.	Axin 1.	0.600
ENSCANP00000012853	SMAD2	ENSCANP00000012853	ENSCANP00000036850	C2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.802
ENSCANP00000012853	SMAD3	ENSCANP00000012853	ENSCANP00000000895	C2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.781
ENSCANP00000012853	SMAD4	ENSCANP00000012853	ENSCANP00000029295	C2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.806