23 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	SMAD9	Mothers against decapentaplegic homolog. (467 aa)
	BMP2	Bone morphogenetic protein 2. (396 aa)
	EP300	E1A binding protein p300. (2409 aa)
	NFE2L2	Nuclear factor, erythroid 2 like 2. (601 aa)
	SMAD5	Mothers against decapentaplegic homolog. (465 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	DLX5	Distal-less homeobox 5. (289 aa)
	RUNX2	RUNX family transcription factor 2. (475 aa)
	XBP1	X-box binding protein 1. (204 aa)
	NOTCH1	Notch receptor 1. (2559 aa)
	SESN2	Sestrin 2. (479 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (827 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (396 aa)
	ATF4	Activating transcription factor 4. (351 aa)
	JUN	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (246 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (548 aa)
	CARF	Calcium responsive transcription factor. (684 aa)
	CREB3	cAMP responsive element binding protein 3. (372 aa)
	MT3	Metallothionein 3; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
	CHD6	Chromodomain helicase DNA binding protein 6. (2714 aa)
	RBPJ	Recombination signal binding protein for immunoglobulin kappa J region. (524 aa)
	ATF2	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF2	ATF4	ENSCANP00000004508	ENSCANP00000031219	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Activating transcription factor 4.	0.849
ATF2	CREB3	ENSCANP00000004508	ENSCANP00000035848	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	cAMP responsive element binding protein 3.	0.846
ATF2	EP300	ENSCANP00000004508	ENSCANP00000014363	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	E1A binding protein p300.	0.915
ATF2	JUN	ENSCANP00000004508	ENSCANP00000031514	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.988
ATF4	ATF2	ENSCANP00000031219	ENSCANP00000004508	Activating transcription factor 4.	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	0.849
ATF4	CREB3	ENSCANP00000031219	ENSCANP00000035848	Activating transcription factor 4.	cAMP responsive element binding protein 3.	0.831
ATF4	EP300	ENSCANP00000031219	ENSCANP00000014363	Activating transcription factor 4.	E1A binding protein p300.	0.938
ATF4	JUN	ENSCANP00000031219	ENSCANP00000031514	Activating transcription factor 4.	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.686
ATF4	NFE2L2	ENSCANP00000031219	ENSCANP00000014602	Activating transcription factor 4.	Nuclear factor, erythroid 2 like 2.	0.578
ATF4	RUNX2	ENSCANP00000031219	ENSCANP00000021159	Activating transcription factor 4.	RUNX family transcription factor 2.	0.475
ATF4	XBP1	ENSCANP00000031219	ENSCANP00000023777	Activating transcription factor 4.	X-box binding protein 1.	0.745
BMP2	DLX5	ENSCANP00000012981	ENSCANP00000020177	Bone morphogenetic protein 2.	Distal-less homeobox 5.	0.595
BMP2	RUNX2	ENSCANP00000012981	ENSCANP00000021159	Bone morphogenetic protein 2.	RUNX family transcription factor 2.	0.705
BMP2	SMAD1	ENSCANP00000012981	ENSCANP00000018106	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.643
BMP2	SMAD4	ENSCANP00000012981	ENSCANP00000029295	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.865
BMP2	SMAD5	ENSCANP00000012981	ENSCANP00000016149	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.699
BMP2	SMAD9	ENSCANP00000012981	ENSCANP00000009753	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.640
CHD6	EP300	ENSCANP00000039553	ENSCANP00000014363	Chromodomain helicase DNA binding protein 6.	E1A binding protein p300.	0.450
CREB3	ATF2	ENSCANP00000035848	ENSCANP00000004508	cAMP responsive element binding protein 3.	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	0.846
CREB3	ATF4	ENSCANP00000035848	ENSCANP00000031219	cAMP responsive element binding protein 3.	Activating transcription factor 4.	0.831