STRINGSTRING
LOC105517842 LOC105517842 MED7 MED7 ENSCANP00000000656 ENSCANP00000000656 MED1 MED1 MED27 MED27 LOC105523459 LOC105523459 MED23 MED23 TAF9 TAF9 PAXIP1 PAXIP1 MED30 MED30 NKX2-5 NKX2-5 HNF1B HNF1B TAF8 TAF8 ENSCANP00000010520 ENSCANP00000010520 TAF5 TAF5 SUB1 SUB1 MED28 MED28 MED8 MED8 MED14 MED14 WNT10B WNT10B TAF4B TAF4B PSMC6 PSMC6 MITF MITF MED16 MED16 MED4 MED4 MED15 MED15 MED22 MED22 TAF2 TAF2 TAF1 TAF1 TAF10 TAF10 TAF4 TAF4 MED21 MED21 MED9 MED9 HNF1A HNF1A MED31 MED31 MED26 MED26 TAF6 TAF6 SRF SRF TAF3 TAF3 ERCC1 ERCC1 TP53 TP53 TAF12 TAF12 MED11 MED11 JUN JUN ERCC6 ERCC6 MED12 MED12 DHX36 DHX36 SETX SETX MED13 MED13 FOSL1 FOSL1 MED29 MED29 ENSCANP00000036083 ENSCANP00000036083 ESR1 ESR1 MED25 MED25 TBP TBP GTF2A2 GTF2A2 BCLAF1 BCLAF1 MED19 MED19 MED24 MED24
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105517842Uncharacterized protein. (253 aa)
MED7Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (232 aa)
ENSCANP00000000656Uncharacterized protein. (178 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1576 aa)
MED27Mediator complex subunit 27. (311 aa)
LOC105523459Btz domain-containing protein. (766 aa)
MED23Mediator complex subunit 23. (1368 aa)
TAF9Uncharacterized protein. (264 aa)
PAXIP1PAX interacting protein 1. (1060 aa)
MED30Mediator complex subunit 30. (178 aa)
NKX2-5NK2 homeobox 5. (324 aa)
HNF1BHNF1 homeobox B. (558 aa)
TAF8TATA-box binding protein associated factor 8. (291 aa)
ENSCANP00000010520PC4 domain-containing protein. (124 aa)
TAF5TATA-box binding protein associated factor 5. (800 aa)
SUB1PC4 domain-containing protein. (127 aa)
MED28Mediator complex subunit 28. (120 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (338 aa)
MED14Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1454 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
TAF4BTATA-box binding protein associated factor 4b. (867 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
MITFMelanocyte inducing transcription factor. (526 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (877 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (255 aa)
MED15Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (787 aa)
MED22Mediator complex subunit 22. (200 aa)
TAF2TATA-box binding protein associated factor 2. (1199 aa)
TAF1Transcription initiation factor TFIID subunit. (1926 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
TAF4TATA-box binding protein associated factor 4. (635 aa)
MED21Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (159 aa)
MED9Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (146 aa)
HNF1AHNF1 homeobox A. (662 aa)
MED31Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa)
MED26TFIIS N-terminal domain-containing protein. (600 aa)
TAF6TATA-box binding protein associated factor 6. (738 aa)
SRFSerum response factor. (406 aa)
TAF3TATA-box binding protein associated factor 3. (879 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (298 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (396 aa)
TAF12TATA-box binding protein associated factor 12. (213 aa)
MED11Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (117 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (246 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1494 aa)
MED12Mediator complex subunit 12. (1988 aa)
DHX36DEAH-box helicase 36. (1008 aa)
SETXSenataxin. (2666 aa)
MED13Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2173 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
MED29Mediator complex subunit 29. (201 aa)
ENSCANP00000036083Uncharacterized protein. (111 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
MED25Mediator complex subunit 25. (747 aa)
TBPTATA-box binding protein. (328 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
BCLAF1BCL2 associated transcription factor 1. (921 aa)
MED19Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (261 aa)
MED24Mediator complex subunit 24. (1008 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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