55 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CDKN2A	Cyclin dependent kinase inhibitor 2A. (159 aa)
	H1-5	Histone cluster 1 H1 family member b. (226 aa)
	CBX3	Chromobox 3. (183 aa)
	SMARCAD1	Uncharacterized protein. (1026 aa)
	BAZ2A	Bromodomain adjacent to zinc finger domain 2A. (1909 aa)
	SUV39H1	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (423 aa)
	WDR76	WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (626 aa)
	RNF20	E3 ubiquitin protein ligase; Belongs to the BRE1 family. (975 aa)
	KMT5C	Lysine methyltransferase 5C. (461 aa)
	AGO1	Argonaute RISC component 1; Belongs to the argonaute family. (857 aa)
	ENSCANP00000032081	Uncharacterized protein. (853 aa)
	MORC2	MORC family CW-type zinc finger 2. (1057 aa)
	ENSCANP00000030231	TTD domain-containing protein. (162 aa)
	LOC105516447	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	HELLS	Helicase, lymphoid specific. (882 aa)
	ENSCANP00000026628	Uncharacterized protein. (95 aa)
	SALL1	Spalt like transcription factor 1. (1318 aa)
	SNAI1	Snail family transcriptional repressor 1. (264 aa)
	BEND3	BEN domain containing 3. (828 aa)
	SIRT2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (388 aa)
	TASOR	Transcription activation suppressor. (1507 aa)
	NCAPD3	Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1498 aa)
	UHRF2	Ubiquitin like with PHD and ring finger domains 2. (802 aa)
	UBE2A	Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	UHRF1	Ubiquitin like with PHD and ring finger domains 1. (850 aa)
	RNF40	E3 ubiquitin protein ligase; Belongs to the BRE1 family. (1001 aa)
	MBD1	Methyl-CpG binding domain protein 1. (642 aa)
	PHC1	Polyhomeotic homolog 1. (1004 aa)
	DNMT1	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1646 aa)
	ENSCANP00000018550	Uncharacterized protein. (83 aa)
	IKZF1	IKAROS family zinc finger 1. (519 aa)
	CBX5	Chromobox 5. (157 aa)
	ENSCANP00000016944	Uncharacterized protein. (90 aa)
	HMGA2	High mobility group AT-hook 2. (147 aa)
	ZBTB18	Zinc finger and BTB domain containing 18. (531 aa)
	CENPC	Centromere protein C. (945 aa)
	LOC105501336	Uncharacterized protein. (153 aa)
	TNKS1BP1	Tankyrase 1 binding protein 1. (1668 aa)
	HMGA1	Uncharacterized protein. (201 aa)
	UBE2B	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (138 aa)
	MECP2	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
	ZNF618	Uncharacterized protein. (953 aa)
	UBE2U	Ubiquitin conjugating enzyme E2 U; Belongs to the ubiquitin-conjugating enzyme family. (300 aa)
	ZFP57	ZFP57 zinc finger protein. (535 aa)
	CBX2	Chromobox 2. (500 aa)
	BAZ2B	Bromodomain adjacent to zinc finger domain 2B. (2168 aa)
	CBX1	Chromobox 1. (268 aa)
	SIRT1	Sirtuin 1. (600 aa)
	MACROH2A1	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
	ENSCANP00000039184	Uncharacterized protein. (167 aa)
	ENSCANP00000038657	Fork-head domain-containing protein. (200 aa)
	ENSCANP00000038326	Uncharacterized protein. (112 aa)
	PSIP1	PC4 and SFRS1 interacting protein 1. (530 aa)
	PHC2	Polyhomeotic homolog 2. (859 aa)
	RRP8	Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (456 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO1	SUV39H1	ENSCANP00000032455	ENSCANP00000012079	Argonaute RISC component 1; Belongs to the argonaute family.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.	0.461
BAZ2A	DNMT1	ENSCANP00000000108	ENSCANP00000019277	Bromodomain adjacent to zinc finger domain 2A.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.423
BAZ2A	HELLS	ENSCANP00000000108	ENSCANP00000028716	Bromodomain adjacent to zinc finger domain 2A.	Helicase, lymphoid specific.	0.757
BAZ2B	DNMT1	ENSCANP00000008808	ENSCANP00000019277	Bromodomain adjacent to zinc finger domain 2B.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.418
BAZ2B	HELLS	ENSCANP00000008808	ENSCANP00000028716	Bromodomain adjacent to zinc finger domain 2B.	Helicase, lymphoid specific.	0.757
CBX1	CBX3	ENSCANP00000008529	ENSCANP00000002610	Chromobox 1.	Chromobox 3.	0.701
CBX1	DNMT1	ENSCANP00000008529	ENSCANP00000019277	Chromobox 1.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.562
CBX1	ENSCANP00000039184	ENSCANP00000008529	ENSCANP00000039184	Chromobox 1.	Uncharacterized protein.	0.673
CBX1	KMT5C	ENSCANP00000008529	ENSCANP00000032499	Chromobox 1.	Lysine methyltransferase 5C.	0.429
CBX1	LOC105501336	ENSCANP00000008529	ENSCANP00000012783	Chromobox 1.	Uncharacterized protein.	0.701
CBX1	SUV39H1	ENSCANP00000008529	ENSCANP00000012079	Chromobox 1.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.	0.832
CBX2	PHC1	ENSCANP00000040325	ENSCANP00000019772	Chromobox 2.	Polyhomeotic homolog 1.	0.960
CBX2	PHC2	ENSCANP00000040325	ENSCANP00000034721	Chromobox 2.	Polyhomeotic homolog 2.	0.931
CBX3	CBX1	ENSCANP00000002610	ENSCANP00000008529	Chromobox 3.	Chromobox 1.	0.701
CBX3	CBX5	ENSCANP00000002610	ENSCANP00000018308	Chromobox 3.	Chromobox 5.	0.510
CBX3	DNMT1	ENSCANP00000002610	ENSCANP00000019277	Chromobox 3.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.441
CBX3	H1-5	ENSCANP00000002610	ENSCANP00000004321	Chromobox 3.	Histone cluster 1 H1 family member b.	0.604
CBX3	SIRT1	ENSCANP00000002610	ENSCANP00000008032	Chromobox 3.	Sirtuin 1.	0.529
CBX3	SUV39H1	ENSCANP00000002610	ENSCANP00000012079	Chromobox 3.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.	0.869
CBX5	CBX3	ENSCANP00000018308	ENSCANP00000002610	Chromobox 5.	Chromobox 3.	0.510