STRINGSTRING
SLC25A46 SLC25A46 LOC105523268 LOC105523268 NEU4 NEU4 ATAD1 ATAD1 PINK1 PINK1 ENSCANP00000024401 ENSCANP00000024401 AMBRA1 AMBRA1 SARM1 SARM1 ENSCANP00000025253 ENSCANP00000025253 BID BID EXD2 EXD2 TIGAR TIGAR SOX10 SOX10 PGAM5 PGAM5 LOC105521129 LOC105521129 RHOT1 RHOT1 HADHB HADHB STARD7 STARD7 QTRT1 QTRT1 ENSCANP00000028764 ENSCANP00000028764 MTX3 MTX3 CISD2 CISD2 TOMM7 TOMM7 TMEM205 TMEM205 SFXN2 SFXN2 ENSCANP00000032046 ENSCANP00000032046 RAB32 RAB32 ENSCANP00000032385 ENSCANP00000032385 GDAP1L1 GDAP1L1 LRRK2 LRRK2 ENSCANP00000033464 ENSCANP00000033464 ACSL1 ACSL1 SAMM50 SAMM50 COASY COASY VAT1 VAT1 FAM210B FAM210B HAX1 HAX1 ENSCANP00000035163 ENSCANP00000035163 AGPAT5 AGPAT5 TOMM70 TOMM70 ACSL4 ACSL4 SPATA18 SPATA18 MFF MFF CPT1A CPT1A RAB11FIP5 RAB11FIP5 IFI27 IFI27 NLRX1 NLRX1 DNAJC11 DNAJC11 LOC105503388 LOC105503388 FUNDC1 FUNDC1 MTCH2 MTCH2 ENSCANP00000039613 ENSCANP00000039613 VPS13C VPS13C SYNJ2BP SYNJ2BP BMF BMF ENSCANP00000036983 ENSCANP00000036983 ENSCANP00000037630 ENSCANP00000037630 GK GK DMPK DMPK LOC105523066 LOC105523066 ERAS ERAS BCL2L1 BCL2L1 MARCHF5 MARCHF5 MOAP1 MOAP1 RPS27A RPS27A ENSCANP00000000073 ENSCANP00000000073 LOC105517589 LOC105517589 LOC105517114 LOC105517114 PRNP PRNP ENSCANP00000011763 ENSCANP00000011763 MFN2 MFN2 TOMM40L TOMM40L PGRMC1 PGRMC1 MUL1 MUL1 ENSCANP00000010024 ENSCANP00000010024 TOMM5 TOMM5 ENSCANP00000009934 ENSCANP00000009934 ENSCANP00000009857 ENSCANP00000009857 BCL2L11 BCL2L11 OPA1 OPA1 GPAT2 GPAT2 ARMC12 ARMC12 CPT1B CPT1B KMO KMO ENSCANP00000008493 ENSCANP00000008493 MIEF2 MIEF2 MSTO1 MSTO1 GPAM GPAM ACACB ACACB BNIP3 BNIP3 FOXO3 FOXO3 GDAP1 GDAP1 SPART SPART ANKZF1 ANKZF1 KRAS KRAS MIEF1 MIEF1 BAD BAD TOMM34 TOMM34 PRKN PRKN NIPSNAP2 NIPSNAP2 BCL2 BCL2 ATF2 ATF2 MTARC1 MTARC1 TOMM22 TOMM22 USP30 USP30 MAOA MAOA LOC105523183 LOC105523183 AIFM2 AIFM2 CHCHD6 CHCHD6 TSPO TSPO MCL1 MCL1 PPP2R2B PPP2R2B CYP27B1 CYP27B1 MFSD11 MFSD11 RPS6KB1 RPS6KB1 MYO19 MYO19 MAVS MAVS MICOS10 MICOS10 RAC2 RAC2 ENSCANP00000015695 ENSCANP00000015695 ENSCANP00000015886 ENSCANP00000015886 MTX1 MTX1 LOC105503496 LOC105503496 CYB5A CYB5A ENSCANP00000017429 ENSCANP00000017429 TOMM20 TOMM20 MTX2 MTX2 PLD6 PLD6 CISD1 CISD1 ACSL3 ACSL3 MTERF3 MTERF3 RHOT2 RHOT2 ENSCANP00000019642 ENSCANP00000019642 TOMM40 TOMM40 HK2 HK2 MGARP MGARP RTN4IP1 RTN4IP1 TOMM20L TOMM20L MFN1 MFN1 SLC8A3 SLC8A3
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
SLC25A46Solute carrier family 25 member 46; Belongs to the mitochondrial carrier (TC 2.A.29) family. (418 aa)
LOC105523268Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (456 aa)
NEU4Neuraminidase 4. (497 aa)
ATAD1AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
PINK1PTEN induced kinase 1. (507 aa)
ENSCANP00000024401Uncharacterized protein. (135 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1298 aa)
SARM1Sterile alpha and TIR motif containing 1. (594 aa)
ENSCANP00000025253Uncharacterized protein. (114 aa)
BIDBH3 interacting domain death agonist. (255 aa)
EXD2Exonuclease 3'-5' domain containing 2. (621 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
SOX10SRY-box transcription factor 10. (466 aa)
PGAM5PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (239 aa)
LOC105521129J domain-containing protein. (478 aa)
RHOT1Ras homolog family member T1. (750 aa)
HADHBHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (475 aa)
STARD7StAR related lipid transfer domain containing 7. (305 aa)
QTRT1Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (403 aa)
ENSCANP00000028764Uncharacterized protein. (183 aa)
MTX3Metaxin 3. (252 aa)
CISD2CDGSH iron sulfur domain 2. (135 aa)
TOMM7Uncharacterized protein. (125 aa)
TMEM205Transmembrane protein 205. (189 aa)
SFXN2Sidoreflexin. (322 aa)
ENSCANP00000032046Miff domain-containing protein. (78 aa)
RAB32RAB32, member RAS oncogene family. (207 aa)
ENSCANP00000032385AAA domain-containing protein; Belongs to the AAA ATPase family. (336 aa)
GDAP1L1Ganglioside induced differentiation associated protein 1 like 1. (386 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
ENSCANP00000033464MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (74 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (698 aa)
SAMM50SAMM50 sorting and assembly machinery component. (493 aa)
COASYCoenzyme A synthase. (564 aa)
VAT1Vesicle amine transport 1. (238 aa)
FAM210BFamily with sequence similarity 210 member B. (170 aa)
HAX1HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (279 aa)
ENSCANP00000035163Uncharacterized protein. (65 aa)
AGPAT51-acylglycerol-3-phosphate O-acyltransferase 5. (364 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (608 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (711 aa)
SPATA18Spermatogenesis associated 18. (538 aa)
MFFMitochondrial fission factor. (342 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
RAB11FIP5FIP-RBD domain-containing protein. (1301 aa)
IFI27Interferon alpha inducible protein 27. (123 aa)
NLRX1NLR family member X1. (972 aa)
DNAJC11DnaJ heat shock protein family (Hsp40) member C11. (535 aa)
LOC105503388HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (266 aa)
FUNDC1FUN14 domain containing 1. (155 aa)
MTCH2Mitochondrial carrier 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (294 aa)
ENSCANP00000039613ZnF_CDGSH domain-containing protein. (107 aa)
VPS13CVacuolar protein sorting 13 homolog C. (3753 aa)
SYNJ2BPSynaptojanin 2 binding protein. (145 aa)
BMFBcl2 modifying factor. (184 aa)
ENSCANP00000036983Tom37 domain-containing protein. (92 aa)
ENSCANP00000037630Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (115 aa)
GKUncharacterized protein; Belongs to the FGGY kinase family. (564 aa)
DMPKDM1 protein kinase. (632 aa)
LOC105523066Uncharacterized protein. (120 aa)
ERASES cell expressed Ras. (233 aa)
BCL2L1BCL2 like 1. (233 aa)
MARCHF5Membrane associated ring-CH-type finger 5. (278 aa)
MOAP1Modulator of apoptosis 1. (351 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSCANP00000000073ZnF_CDGSH domain-containing protein. (108 aa)
LOC105517589Uncharacterized protein. (74 aa)
LOC105517114Ubiquitin-like domain-containing protein. (156 aa)
PRNPMajor prion protein; Belongs to the prion family. (253 aa)
ENSCANP00000011763Uncharacterized protein. (71 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (387 aa)
TOMM40LTranslocase of outer mitochondrial membrane 40 like. (308 aa)
PGRMC1Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family. (195 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
ENSCANP00000010024Uncharacterized protein. (114 aa)
TOMM5Translocase of outer mitochondrial membrane 5. (84 aa)
ENSCANP00000009934ZnF_CDGSH domain-containing protein. (90 aa)
ENSCANP00000009857Uncharacterized protein. (132 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1015 aa)
GPAT2Glycerol-3-phosphate acyltransferase 2, mitochondrial. (795 aa)
ARMC12Armadillo repeat containing 12. (367 aa)
CPT1BCarnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (485 aa)
ENSCANP00000008493ZnF_CDGSH domain-containing protein. (92 aa)
MIEF2Mitochondrial elongation factor 2. (465 aa)
MSTO1Misato mitochondrial distribution and morphology regulator 1. (570 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
ACACBAcetyl-CoA carboxylase beta. (2438 aa)
BNIP3BCL2 interacting protein 3. (185 aa)
FOXO3Forkhead box O3. (544 aa)
GDAP1Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily. (358 aa)
SPARTSpartin. (666 aa)
ANKZF1Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1. (727 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
MIEF1Mitochondrial elongation factor 1. (478 aa)
BADBCL2 associated agonist of cell death. (167 aa)
TOMM34Translocase of outer mitochondrial membrane 34. (309 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
NIPSNAP2Nipsnap homolog 2. (270 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
MTARC1MOSC domain-containing protein. (337 aa)
TOMM22Uncharacterized protein. (142 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (501 aa)
MAOAAmine oxidase. (527 aa)
LOC105523183Ubiquitin-like domain-containing protein. (77 aa)
AIFM2Apoptosis inducing factor mitochondria associated 2. (373 aa)
CHCHD6MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (256 aa)
TSPOUncharacterized protein. (65 aa)
MCL1MCL1 apoptosis regulator, BCL2 family member. (349 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (509 aa)
MFSD11Major facilitator superfamily domain containing 11. (449 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
MYO19Myosin XIX; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (962 aa)
MAVSUncharacterized protein. (401 aa)
MICOS10MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (78 aa)
RAC2Rac family small GTPase 2. (192 aa)
ENSCANP00000015695Uncharacterized protein. (367 aa)
ENSCANP00000015886Uncharacterized protein. (120 aa)
MTX1Metaxin. (317 aa)
LOC105503496Ubiquitin-like domain-containing protein. (147 aa)
CYB5ACytochrome b5 type A; Belongs to the cytochrome b5 family. (134 aa)
ENSCANP00000017429MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (69 aa)
TOMM20Translocase of outer mitochondrial membrane 20. (145 aa)
MTX2Metaxin 2. (263 aa)
PLD6Phospholipase D family member 6. (172 aa)
CISD1CDGSH iron sulfur domain 1. (108 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (720 aa)
MTERF3Mitochondrial transcription termination factor 3. (417 aa)
RHOT2Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (605 aa)
ENSCANP00000019642Ribosomal_S27 domain-containing protein. (93 aa)
TOMM40Translocase of outer mitochondrial membrane 40. (292 aa)
HK2Hexokinase 2. (917 aa)
MGARPMitochondria localized glutamic acid rich protein. (240 aa)
RTN4IP1Reticulon 4 interacting protein 1. (396 aa)
TOMM20LTranslocase of outer mitochondrial membrane 20 like. (155 aa)
MFN1Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (696 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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