(50 nodes) SCF ubiquitin ligase complex network (Colobus angolensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FBXW5	F-box and WD repeat domain containing 5. (566 aa)
	CCNF	Cyclin F; Belongs to the cyclin family. (742 aa)
	RBX1	Ring-box 1. (108 aa)
	ENSCANP00000002256	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (86 aa)
	FBXO27	F-box protein 27. (156 aa)
	FBXO32	F-box protein 32. (360 aa)
	SKP1	S-phase kinase associated protein 1; Belongs to the SKP1 family. (165 aa)
	CKS1B	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
	FBXO38	F-box protein 38. (1113 aa)
	FBXO41	F-box protein 41. (714 aa)
	FBXO9	F-box protein 9. (444 aa)
	FBXO31	F-box protein 31. (482 aa)
	FBXL7	F-box and leucine rich repeat protein 7. (491 aa)
	FBXL22	F-box and leucine rich repeat protein 22. (247 aa)
	FBXL12	F-box and leucine rich repeat protein 12. (326 aa)
	TMEM183A	Uncharacterized protein. (376 aa)
	ENSCANP00000024200	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (65 aa)
	CKS2	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
	FBXL17	F-box and leucine rich repeat protein 17. (445 aa)
	FBXO25	F-box protein 25. (367 aa)
	ENSCANP00000025746	Uncharacterized protein; Belongs to the SKP1 family. (167 aa)
	FBXO45	F-box protein 45. (259 aa)
	ENSCANP00000028184	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
	FBXL15	F-box and leucine rich repeat protein 15. (300 aa)
	FBXO2	F-box protein 2. (295 aa)
	ENSCANP00000033944	Uncharacterized protein; Belongs to the SKP1 family. (131 aa)
	FBXW7	F-box and WD repeat domain containing 7. (707 aa)
	FBXW11	F-box and WD repeat domain containing 11. (542 aa)
	ENSCANP00000031390	Uncharacterized protein. (393 aa)
	SKP2	S-phase kinase associated protein 2. (424 aa)
	FBXO17	F-box protein 17. (278 aa)
	FBXO33	F-box protein 33. (555 aa)
	ENSCANP00000029524	Uncharacterized protein. (315 aa)
	FLI1	Fli-1 proto-oncogene, ETS transcription factor. (452 aa)
	FBXO44	Uncharacterized protein. (255 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (776 aa)
	FBXO42	F-box protein 42. (716 aa)
	USP47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1375 aa)
	BTRC	Beta-transducin repeat containing E3 ubiquitin protein ligase. (527 aa)
	ZC3HC1	Zinc finger C3HC-type containing 1. (502 aa)
	FBXL2	F-box and leucine rich repeat protein 2. (423 aa)
	FBXL14	F-box and leucine rich repeat protein 14. (418 aa)
	FBXL5	F-box and leucine rich repeat protein 5. (672 aa)
	FBXL19	F-box and leucine rich repeat protein 19. (689 aa)
	FBH1	F-box DNA helicase 1. (1044 aa)
	FBXL21P	Uncharacterized protein. (377 aa)
	FBXL3	F-box and leucine rich repeat protein 3. (428 aa)
	LRRC29	Leucine rich repeat containing 29. (225 aa)
	FBXO4	F-box protein 4. (324 aa)
	ENSCANP00000018891	Uncharacterized protein; Belongs to the SKP1 family. (137 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTRC	CCNF	ENSCANP00000011123	ENSCANP00000003835	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Cyclin F; Belongs to the cyclin family.	0.567
BTRC	CUL1	ENSCANP00000011123	ENSCANP00000009974	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Cullin 1; Belongs to the cullin family.	0.998
BTRC	ENSCANP00000018891	ENSCANP00000011123	ENSCANP00000018891	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Uncharacterized protein; Belongs to the SKP1 family.	0.945
BTRC	ENSCANP00000025746	ENSCANP00000011123	ENSCANP00000025746	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Uncharacterized protein; Belongs to the SKP1 family.	0.945
BTRC	ENSCANP00000033944	ENSCANP00000011123	ENSCANP00000033944	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Uncharacterized protein; Belongs to the SKP1 family.	0.927
BTRC	FBXL14	ENSCANP00000011123	ENSCANP00000013115	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box and leucine rich repeat protein 14.	0.443
BTRC	FBXL3	ENSCANP00000011123	ENSCANP00000016215	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box and leucine rich repeat protein 3.	0.472
BTRC	FBXO2	ENSCANP00000011123	ENSCANP00000009292	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box protein 2.	0.890
BTRC	FBXO4	ENSCANP00000011123	ENSCANP00000018510	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box protein 4.	0.845
BTRC	FBXO44	ENSCANP00000011123	ENSCANP00000009920	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Uncharacterized protein.	0.524
BTRC	FBXW11	ENSCANP00000011123	ENSCANP00000031463	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box and WD repeat domain containing 11.	0.965
BTRC	FBXW7	ENSCANP00000011123	ENSCANP00000033209	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box and WD repeat domain containing 7.	0.905
BTRC	RBX1	ENSCANP00000011123	ENSCANP00000003492	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Ring-box 1.	0.992
BTRC	SKP1	ENSCANP00000011123	ENSCANP00000028305	Beta-transducin repeat containing E3 ubiquitin protein ligase.	S-phase kinase associated protein 1; Belongs to the SKP1 family.	0.945
BTRC	SKP2	ENSCANP00000011123	ENSCANP00000031034	Beta-transducin repeat containing E3 ubiquitin protein ligase.	S-phase kinase associated protein 2.	0.939
BTRC	USP47	ENSCANP00000011123	ENSCANP00000010585	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family.	0.672
CCNF	BTRC	ENSCANP00000003835	ENSCANP00000011123	Cyclin F; Belongs to the cyclin family.	Beta-transducin repeat containing E3 ubiquitin protein ligase.	0.567
CCNF	CKS1B	ENSCANP00000003835	ENSCANP00000037001	Cyclin F; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.578
CCNF	CKS2	ENSCANP00000003835	ENSCANP00000024332	Cyclin F; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.578
CCNF	CUL1	ENSCANP00000003835	ENSCANP00000009974	Cyclin F; Belongs to the cyclin family.	Cullin 1; Belongs to the cullin family.	0.946