18 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TAF6	TATA-box binding protein associated factor 6. (738 aa)
	SENP3	ULP_PROTEASE domain-containing protein. (573 aa)
	MGA	MAX dimerization protein MGA. (3069 aa)
	TAF7L	TATA-box binding protein associated factor 7 like. (460 aa)
	TAF1	Transcription initiation factor TFIID subunit. (1926 aa)
	RNF2	Ring finger protein 2. (336 aa)
	E2F6	E2F transcription factor 6. (281 aa)
	CHD8	Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2581 aa)
	HCFC1	Host cell factor C1. (2080 aa)
	ENSCANP00000013426	RING-type domain-containing protein. (324 aa)
	KMT2A	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3914 aa)
	MXD3	MAX dimerization protein 3. (350 aa)
	TEX10	Testis expressed 10. (929 aa)
	MEN1	Menin 1. (610 aa)
	PHF20	PHD finger protein 20. (1014 aa)
	TAF4	TATA-box binding protein associated factor 4. (635 aa)
	C17orf49	Chromosome 17 open reading frame 49. (192 aa)
	PELP1	Proline, glutamate and leucine rich protein 1. (1180 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHD8	KMT2A	ENSCANP00000038559	ENSCANP00000007956	Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...]	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.496
CHD8	PHF20	ENSCANP00000038559	ENSCANP00000018759	Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...]	PHD finger protein 20.	0.458
CHD8	TAF1	ENSCANP00000038559	ENSCANP00000019069	Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...]	Transcription initiation factor TFIID subunit.	0.645
E2F6	ENSCANP00000013426	ENSCANP00000034173	ENSCANP00000013426	E2F transcription factor 6.	RING-type domain-containing protein.	0.921
E2F6	HCFC1	ENSCANP00000034173	ENSCANP00000015982	E2F transcription factor 6.	Host cell factor C1.	0.472
E2F6	KMT2A	ENSCANP00000034173	ENSCANP00000007956	E2F transcription factor 6.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.439
E2F6	MGA	ENSCANP00000034173	ENSCANP00000029423	E2F transcription factor 6.	MAX dimerization protein MGA.	0.943
E2F6	RNF2	ENSCANP00000034173	ENSCANP00000032891	E2F transcription factor 6.	Ring finger protein 2.	0.921
E2F6	TAF1	ENSCANP00000034173	ENSCANP00000019069	E2F transcription factor 6.	Transcription initiation factor TFIID subunit.	0.587
ENSCANP00000013426	E2F6	ENSCANP00000013426	ENSCANP00000034173	RING-type domain-containing protein.	E2F transcription factor 6.	0.921
ENSCANP00000013426	KMT2A	ENSCANP00000013426	ENSCANP00000007956	RING-type domain-containing protein.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.484
ENSCANP00000013426	MGA	ENSCANP00000013426	ENSCANP00000029423	RING-type domain-containing protein.	MAX dimerization protein MGA.	0.708
HCFC1	E2F6	ENSCANP00000015982	ENSCANP00000034173	Host cell factor C1.	E2F transcription factor 6.	0.472
HCFC1	KMT2A	ENSCANP00000015982	ENSCANP00000007956	Host cell factor C1.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.778
HCFC1	PHF20	ENSCANP00000015982	ENSCANP00000018759	Host cell factor C1.	PHD finger protein 20.	0.794
KMT2A	CHD8	ENSCANP00000007956	ENSCANP00000038559	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...]	0.496
KMT2A	E2F6	ENSCANP00000007956	ENSCANP00000034173	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	E2F transcription factor 6.	0.439
KMT2A	ENSCANP00000013426	ENSCANP00000007956	ENSCANP00000013426	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	RING-type domain-containing protein.	0.484
KMT2A	HCFC1	ENSCANP00000007956	ENSCANP00000015982	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	Host cell factor C1.	0.778
KMT2A	MEN1	ENSCANP00000007956	ENSCANP00000001643	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	Menin 1.	0.992