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FGFR3 FGFR3 LOC105508112 LOC105508112 TIE1 TIE1 ABL1 ABL1 EPHA8 EPHA8 KDR KDR BMPR2 BMPR2 ITK ITK POMK POMK BMX BMX FLT4 FLT4 ABL2 ABL2 EPHB2 EPHB2 KSR2 KSR2 TEX14 TEX14 RIPK2 RIPK2 GUCY2D GUCY2D NTRK3 NTRK3 ROS1 ROS1 IRAK4 IRAK4 PTK7 PTK7 NTRK1 NTRK1 FLT1 FLT1 TXK TXK BTK BTK HCK HCK MUSK MUSK TEC TEC EPHB6 EPHB6 AXL AXL TNK1 TNK1 DSTYK DSTYK FER FER ENSCANP00000024565 ENSCANP00000024565 CSF1R CSF1R MET MET ARAF ARAF ILK ILK FGFR4 FGFR4 EPHB4 EPHB4 LMTK2 LMTK2 TYK2 TYK2 SRMS SRMS FGFR2 FGFR2 EPHA6 EPHA6 RAF1 RAF1 EGFR EGFR FYN FYN SYK SYK RYK RYK LMTK3 LMTK3 FRK FRK MST1R MST1R SRC SRC MAP3K10 MAP3K10 MAP3K13 MAP3K13 LCK LCK ZAP70 ZAP70 STYK1 STYK1 PTK2 PTK2 MAP3K12 MAP3K12 FGFR1 FGFR1 FES FES KSR1 KSR1 LYN LYN GUCY2F GUCY2F EPHA10 EPHA10 LOC105523238 LOC105523238 PTK6 PTK6 YES1 YES1 FLT3 FLT3 EPHA7 EPHA7 NEK6 NEK6 BRAF BRAF KIT KIT MAP3K20 MAP3K20 JAK1 JAK1 EPHB1 EPHB1 ROR2 ROR2 ERBB4 ERBB4 NPR2 NPR2 EPHB3 EPHB3 BMPR1A BMPR1A NPR1 NPR1 DDR2 DDR2 IGF1R IGF1R ACVR1 ACVR1 FGR FGR EPHA5 EPHA5 LIMK2 LIMK2 LOC105505122 LOC105505122 EPHA3 EPHA3 PTK2B PTK2B CSK CSK NEK7 NEK7 ACVRL1 ACVRL1 TYRO3 TYRO3 ENSCANP00000009565 ENSCANP00000009565 PDGFRB PDGFRB NTRK2 NTRK2 RET RET TNK2 TNK2 ACVR1C ACVR1C INSRR INSRR ERBB2 ERBB2 RIPK1 RIPK1 BMPR1B BMPR1B ERBB3 ERBB3 BLK BLK MAP3K9 MAP3K9 ALK ALK MATK MATK MAP3K7 MAP3K7 INSR INSR MERTK MERTK TGFBR2 TGFBR2 LIMK1 LIMK1 GUCY2C GUCY2C ROR1 ROR1 LTK LTK DDR1 DDR1 TESK1 TESK1 PDGFRA PDGFRA EPHA1 EPHA1 JAK3 JAK3 AATK AATK TESK2 TESK2 EPHA4 EPHA4 MAP3K11 MAP3K11 JAK2 JAK2 EPHA2 EPHA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGFR3Fibroblast growth factor receptor. (808 aa)
LOC105508112Uncharacterized protein. (835 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
EPHA8EPH receptor A8. (990 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1030 aa)
ITKTyrosine-protein kinase. (620 aa)
POMKProtein O-mannose kinase. (350 aa)
BMXTyrosine-protein kinase. (675 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1342 aa)
ABL2ABL proto-oncogene 2, non-receptor tyrosine kinase. (850 aa)
EPHB2EPH receptor B2. (1082 aa)
KSR2Kinase suppressor of ras 2. (903 aa)
TEX14Testis expressed 14, intercellular bridge forming factor. (1392 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
GUCY2DGuanylate cyclase. (956 aa)
NTRK3Tyrosine-protein kinase receptor. (865 aa)
ROS1Tyrosine-protein kinase receptor. (2346 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (438 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1078 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1255 aa)
TXKTyrosine-protein kinase. (527 aa)
BTKTyrosine-protein kinase. (692 aa)
HCKTyrosine-protein kinase. (525 aa)
MUSKMuscle associated receptor tyrosine kinase. (881 aa)
TECTyrosine-protein kinase. (630 aa)
EPHB6EPH receptor B6. (1019 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
TNK1Tyrosine kinase non receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (659 aa)
DSTYKDual serine/threonine and tyrosine protein kinase. (931 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
ENSCANP00000024565Protein kinase domain-containing protein. (346 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (974 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1404 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (587 aa)
ILKIntegrin linked kinase. (526 aa)
FGFR4Fibroblast growth factor receptor. (802 aa)
EPHB4EPH receptor B4. (987 aa)
LMTK2Lemur tyrosine kinase 2. (1486 aa)
TYK2Tyrosine-protein kinase. (1187 aa)
SRMSTyrosine-protein kinase. (492 aa)
FGFR2Fibroblast growth factor receptor. (838 aa)
EPHA6EPH receptor A6. (1130 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
EGFRReceptor protein-tyrosine kinase. (1188 aa)
FYNTyrosine-protein kinase. (537 aa)
SYKTyrosine-protein kinase. (635 aa)
RYKReceptor like tyrosine kinase. (529 aa)
LMTK3Lemur tyrosine kinase 3. (989 aa)
FRKTyrosine-protein kinase. (505 aa)
MST1RMacrophage stimulating 1 receptor. (1400 aa)
SRCTyrosine-protein kinase. (458 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase 10. (777 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13. (700 aa)
LCKTyrosine-protein kinase. (539 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
STYK1Serine/threonine/tyrosine kinase 1. (422 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (890 aa)
FGFR1Fibroblast growth factor receptor. (815 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (829 aa)
KSR1Kinase suppressor of ras 1. (867 aa)
LYNTyrosine-protein kinase. (512 aa)
GUCY2FGuanylate cyclase. (1108 aa)
EPHA10EPH receptor A10. (897 aa)
LOC105523238Uncharacterized protein. (681 aa)
PTK6Tyrosine-protein kinase. (451 aa)
YES1Tyrosine-protein kinase. (548 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (995 aa)
EPHA7EPH receptor A7. (998 aa)
NEK6NIMA related kinase 6; Belongs to the protein kinase superfamily. (347 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (747 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (800 aa)
JAK1Tyrosine-protein kinase. (1159 aa)
EPHB1EPH receptor B1. (984 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1079 aa)
ERBB4Receptor protein-tyrosine kinase. (1283 aa)
NPR2Guanylate cyclase. (1047 aa)
EPHB3EPH receptor B3. (1008 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
NPR1Guanylate cyclase. (958 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (855 aa)
IGF1RTyrosine-protein kinase receptor. (1335 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
FGRTyrosine-protein kinase. (529 aa)
EPHA5EPH receptor A5. (1038 aa)
LIMK2LIM domain kinase 2. (643 aa)
LOC105505122Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (765 aa)
EPHA3EPH receptor A3. (984 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
CSKTyrosine-protein kinase. (450 aa)
NEK7NIMA related kinase 7; Belongs to the protein kinase superfamily. (302 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
TYRO3TYRO3 protein tyrosine kinase. (897 aa)
ENSCANP00000009565Uncharacterized protein. (651 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1089 aa)
TNK2Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1054 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (489 aa)
INSRRTyrosine-protein kinase receptor. (1301 aa)
ERBB2Receptor protein-tyrosine kinase. (1259 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (625 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1330 aa)
BLKTyrosine-protein kinase. (505 aa)
MAP3K9Mitogen-activated protein kinase kinase kinase. (997 aa)
ALKTyrosine-protein kinase receptor. (1388 aa)
MATKTyrosine-protein kinase. (507 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
INSRTyrosine-protein kinase receptor. (1388 aa)
MERTKMER proto-oncogene, tyrosine kinase. (999 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
LIMK1LIM domain kinase 1. (677 aa)
GUCY2CGuanylate cyclase. (1073 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (923 aa)
LTKTyrosine-protein kinase receptor. (803 aa)
DDR1Discoidin domain receptor tyrosine kinase 1. (894 aa)
TESK1Testis associated actin remodelling kinase 1. (595 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
EPHA1Receptor protein-tyrosine kinase. (948 aa)
JAK3Tyrosine-protein kinase. (1124 aa)
AATKApoptosis associated tyrosine kinase. (1258 aa)
TESK2Testis associated actin remodelling kinase 2. (572 aa)
EPHA4EPH receptor A4. (986 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (847 aa)
JAK2Tyrosine-protein kinase. (1139 aa)
EPHA2EPH receptor A2. (976 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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