(20 nodes) Thioredoxin, conserved site network (Colobus angolensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TXNDC5	Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family. (356 aa)
	TXNDC8	Thioredoxin domain containing 8. (127 aa)
	PDIA4	Protein disulfide-isomerase. (646 aa)
	PDIA5	Protein disulfide isomerase family A member 5. (519 aa)
	LOC105501334	Thioredoxin; Belongs to the thioredoxin family. (101 aa)
	DNAJC10	DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. (793 aa)
	PDIA6	Protein disulfide isomerase family A member 6. (444 aa)
	NME9	NME/NM23 family member 9; Belongs to the NDK family. (330 aa)
	TXNL1	Thioredoxin like 1. (289 aa)
	PDIA2	Protein disulfide isomerase family A member 2. (525 aa)
	PDIA3	Protein disulfide-isomerase. (485 aa)
	TXNDC12	Thioredoxin domain containing 12. (123 aa)
	TMX1	Thioredoxin related transmembrane protein 1. (280 aa)
	LOC105503376	Thioredoxin domain-containing protein. (104 aa)
	TMX4	Thioredoxin related transmembrane protein 4. (349 aa)
	TXN2	Thioredoxin 2. (166 aa)
	TMX3	Thioredoxin related transmembrane protein 3. (454 aa)
	P4HB	Protein disulfide-isomerase. (506 aa)
	NME8	NME/NM23 family member 8. (588 aa)
	TXN	Thioredoxin; Belongs to the thioredoxin family. (105 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DNAJC10	NME8	ENSCANP00000023317	ENSCANP00000029456	DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.	NME/NM23 family member 8.	0.811
DNAJC10	P4HB	ENSCANP00000023317	ENSCANP00000029749	DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.	Protein disulfide-isomerase.	0.710
DNAJC10	PDIA2	ENSCANP00000023317	ENSCANP00000016809	DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.	Protein disulfide isomerase family A member 2.	0.566
DNAJC10	PDIA3	ENSCANP00000023317	ENSCANP00000028380	DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.	Protein disulfide-isomerase.	0.566
DNAJC10	PDIA4	ENSCANP00000023317	ENSCANP00000023829	DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.	Protein disulfide-isomerase.	0.566
DNAJC10	PDIA5	ENSCANP00000023317	ENSCANP00000023646	DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.	Protein disulfide isomerase family A member 5.	0.424
LOC105501334	TXN2	ENSCANP00000023364	ENSCANP00000034819	Thioredoxin; Belongs to the thioredoxin family.	Thioredoxin 2.	0.653
LOC105501334	TXNDC8	ENSCANP00000023364	ENSCANP00000027783	Thioredoxin; Belongs to the thioredoxin family.	Thioredoxin domain containing 8.	0.473
LOC105503376	TXN	ENSCANP00000001041	ENSCANP00000028402	Thioredoxin domain-containing protein.	Thioredoxin; Belongs to the thioredoxin family.	0.771
LOC105503376	TXN2	ENSCANP00000001041	ENSCANP00000034819	Thioredoxin domain-containing protein.	Thioredoxin 2.	0.752
LOC105503376	TXNDC8	ENSCANP00000001041	ENSCANP00000027783	Thioredoxin domain-containing protein.	Thioredoxin domain containing 8.	0.465
NME8	DNAJC10	ENSCANP00000029456	ENSCANP00000023317	NME/NM23 family member 8.	DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.	0.811
NME8	TXN2	ENSCANP00000029456	ENSCANP00000034819	NME/NM23 family member 8.	Thioredoxin 2.	0.670
NME9	TXN2	ENSCANP00000019391	ENSCANP00000034819	NME/NM23 family member 9; Belongs to the NDK family.	Thioredoxin 2.	0.535
P4HB	DNAJC10	ENSCANP00000029749	ENSCANP00000023317	Protein disulfide-isomerase.	DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.	0.710
P4HB	PDIA3	ENSCANP00000029749	ENSCANP00000028380	Protein disulfide-isomerase.	Protein disulfide-isomerase.	0.691
P4HB	PDIA4	ENSCANP00000029749	ENSCANP00000023829	Protein disulfide-isomerase.	Protein disulfide-isomerase.	0.931
P4HB	PDIA6	ENSCANP00000029749	ENSCANP00000020200	Protein disulfide-isomerase.	Protein disulfide isomerase family A member 6.	0.942
P4HB	TXNDC5	ENSCANP00000029749	ENSCANP00000014916	Protein disulfide-isomerase.	Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family.	0.926
PDIA2	DNAJC10	ENSCANP00000016809	ENSCANP00000023317	Protein disulfide isomerase family A member 2.	DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.	0.566