42 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RAD18	RAD18 E3 ubiquitin protein ligase. (496 aa)
	ENSCANP00000026071	RFC1 domain-containing protein. (136 aa)
	WDR48	WD repeat domain 48. (677 aa)
	RFC4	Replication factor C subunit 4. (363 aa)
	POLE2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
	MEIOB	Meiosis specific with OB-fold. (392 aa)
	POLD3	Uncharacterized protein. (454 aa)
	CUL4B	Cullin 4B; Belongs to the cullin family. (870 aa)
	ENSCANP00000032089	Uncharacterized protein. (120 aa)
	LOC105523183	Ubiquitin-like domain-containing protein. (77 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
	ATAD5	ATPase family AAA domain containing 5. (1726 aa)
	RFC5	Replication factor C subunit 5. (343 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2267 aa)
	POLD2	DNA polymerase delta 2, accessory subunit. (504 aa)
	LOC105521899	Ubiquitin-like domain-containing protein. (146 aa)
	RFC3	Replication factor C subunit 3. (356 aa)
	ENSCANP00000000485	Ubiquitin-like domain-containing protein. (72 aa)
	RCBTB2	RCC1 and BTB domain containing protein 2. (561 aa)
	DTL	Denticleless E3 ubiquitin protein ligase homolog. (702 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (574 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	LOC105503496	Ubiquitin-like domain-containing protein. (147 aa)
	POLE4	DNA polymerase epsilon 4, accessory subunit. (116 aa)
	POLD4	Uncharacterized protein. (107 aa)
	ENSCANP00000007912	Ubiquitin-like domain-containing protein. (121 aa)
	RPA3	Replication protein A3. (121 aa)
	POLE3	DNA polymerase epsilon 3, accessory subunit. (147 aa)
	RFC1	Replication factor C subunit 1. (1148 aa)
	RFC2	Replication factor C subunit 2. (341 aa)
	RCBTB1	RCC1 and BTB domain containing protein 1. (531 aa)
	USP1	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (783 aa)
	DDB1	Damage specific DNA binding protein 1. (1147 aa)
	LOC105509448	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (245 aa)
	ENSCANP00000004759	Ubiquitin-like domain-containing protein. (147 aa)
	RBX1	Ring-box 1. (108 aa)
	CUL4A	Cullin 4A; Belongs to the cullin family. (587 aa)
	LOC105517114	Ubiquitin-like domain-containing protein. (156 aa)
	POLD1	DNA polymerase delta 1, catalytic subunit. (1012 aa)
	ENSCANP00000019642	Ribosomal_S27 domain-containing protein. (93 aa)
	ENSCANP00000022288	Ubiquitin-like domain-containing protein. (79 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	CUL4A	ENSCANP00000011146	ENSCANP00000003344	ATPase family AAA domain containing 5.	Cullin 4A; Belongs to the cullin family.	0.498
ATAD5	CUL4B	ENSCANP00000011146	ENSCANP00000012282	ATPase family AAA domain containing 5.	Cullin 4B; Belongs to the cullin family.	0.498
ATAD5	DDB1	ENSCANP00000011146	ENSCANP00000006468	ATPase family AAA domain containing 5.	Damage specific DNA binding protein 1.	0.570
ATAD5	DTL	ENSCANP00000011146	ENSCANP00000014573	ATPase family AAA domain containing 5.	Denticleless E3 ubiquitin protein ligase homolog.	0.871
ATAD5	ENSCANP00000026071	ENSCANP00000011146	ENSCANP00000026071	ATPase family AAA domain containing 5.	RFC1 domain-containing protein.	0.537
ATAD5	ENSCANP00000032089	ENSCANP00000011146	ENSCANP00000032089	ATPase family AAA domain containing 5.	Uncharacterized protein.	0.485
ATAD5	LOC105509448	ENSCANP00000011146	ENSCANP00000005226	ATPase family AAA domain containing 5.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.949
ATAD5	MEIOB	ENSCANP00000011146	ENSCANP00000030325	ATPase family AAA domain containing 5.	Meiosis specific with OB-fold.	0.718
ATAD5	PCNA	ENSCANP00000011146	ENSCANP00000015524	ATPase family AAA domain containing 5.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.949
ATAD5	POLD1	ENSCANP00000011146	ENSCANP00000019067	ATPase family AAA domain containing 5.	DNA polymerase delta 1, catalytic subunit.	0.803
ATAD5	POLD2	ENSCANP00000011146	ENSCANP00000000021	ATPase family AAA domain containing 5.	DNA polymerase delta 2, accessory subunit.	0.660
ATAD5	POLE	ENSCANP00000011146	ENSCANP00000038530	ATPase family AAA domain containing 5.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.902
ATAD5	POLE2	ENSCANP00000011146	ENSCANP00000030322	ATPase family AAA domain containing 5.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.821
ATAD5	POLE3	ENSCANP00000011146	ENSCANP00000007437	ATPase family AAA domain containing 5.	DNA polymerase epsilon 3, accessory subunit.	0.725
ATAD5	POLE4	ENSCANP00000011146	ENSCANP00000039824	ATPase family AAA domain containing 5.	DNA polymerase epsilon 4, accessory subunit.	0.684
ATAD5	RAD18	ENSCANP00000011146	ENSCANP00000002030	ATPase family AAA domain containing 5.	RAD18 E3 ubiquitin protein ligase.	0.798
ATAD5	RFC1	ENSCANP00000011146	ENSCANP00000007965	ATPase family AAA domain containing 5.	Replication factor C subunit 1.	0.537
ATAD5	RFC2	ENSCANP00000011146	ENSCANP00000007354	ATPase family AAA domain containing 5.	Replication factor C subunit 2.	0.982
ATAD5	RFC3	ENSCANP00000011146	ENSCANP00000013590	ATPase family AAA domain containing 5.	Replication factor C subunit 3.	0.988
ATAD5	RFC4	ENSCANP00000011146	ENSCANP00000029254	ATPase family AAA domain containing 5.	Replication factor C subunit 4.	0.990