STRINGSTRING
SUPT4H1 SUPT4H1 CDK7 CDK7 ENSCANP00000022785 ENSCANP00000022785 POLR2C POLR2C NELFCD NELFCD CTDP1 CTDP1 CCNH CCNH NCBP1 NCBP1 GTF2H5 GTF2H5 GTF2H1 GTF2H1 ENSCANP00000021879 ENSCANP00000021879 MNAT1 MNAT1 LOC105509844 LOC105509844 LOC105524160 LOC105524160 NELFB NELFB POLR2I POLR2I LOC105503213 LOC105503213 GTF2F1 GTF2F1 POLR2E POLR2E POLR2H POLR2H GTF2F2 GTF2F2 NELFE NELFE POLR2A POLR2A LOC105508545 LOC105508545 ERCC3 ERCC3 NELFA NELFA NCBP2 NCBP2 LOC105517070 LOC105517070 ERCC2 ERCC2 ENSCANP00000035075 ENSCANP00000035075 POLR2K POLR2K POLR2B POLR2B POLR2F POLR2F POLR2L POLR2L POLR2G POLR2G C6orf15 C6orf15 GTF2H4 GTF2H4 POLR2D POLR2D SUPT5H SUPT5H
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SUPT4H1Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa)
CDK7Cyclin dependent kinase 7. (309 aa)
ENSCANP00000022785Protein kinase domain-containing protein. (322 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
NELFCDUncharacterized protein. (581 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (859 aa)
CCNHCyclin H; Belongs to the cyclin family. (339 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
GTF2H1General transcription factor IIH subunit 1. (557 aa)
ENSCANP00000021879Uncharacterized protein. (88 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
LOC105509844Uncharacterized protein. (577 aa)
LOC105524160General transcription factor IIH subunit. (395 aa)
NELFBNegative elongation factor complex member B. (573 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (105 aa)
LOC105503213Uncharacterized protein. (266 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (454 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
POLR2HRNA polymerase II subunit H. (175 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
NELFENegative elongation factor complex member E. (395 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1986 aa)
LOC105508545Uncharacterized protein. (162 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
NELFANegative elongation factor complex member A. (481 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (138 aa)
LOC105517070Uncharacterized protein. (488 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
ENSCANP00000035075Uncharacterized protein. (208 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
POLR2FRNA polymerase II subunit F. (158 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
POLR2GRNA polymerase II subunit G. (231 aa)
C6orf15Chromosome 6 open reading frame 15. (312 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
SUPT5HTranscription elongation factor SPT5. (1087 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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