STRINGSTRING
FYN FYN NRG4 NRG4 PIK3CA PIK3CA LOC105503496 LOC105503496 CUL5 CUL5 LOC105504658 LOC105504658 AKT1 AKT1 ERBB4 ERBB4 PLCG1 PLCG1 LOC105523183 LOC105523183 UBA52 UBA52 NRG2 NRG2 HSP90AA1 HSP90AA1 ENSCANP00000008262 ENSCANP00000008262 ERBB2 ERBB2 RHOA RHOA ENSCANP00000007912 ENSCANP00000007912 RNF41 RNF41 ERBB3 ERBB3 KRAS KRAS MATK MATK MEMO1 MEMO1 HBEGF HBEGF HRAS HRAS ENSCANP00000004759 ENSCANP00000004759 PRKCD PRKCD FNDC3A FNDC3A STUB1 STUB1 PRKCA PRKCA LOC105517114 LOC105517114 ERAS ERAS LOC105521899 LOC105521899 ENSCANP00000000485 ENSCANP00000000485 RPS27A RPS27A CDC37 CDC37 ERBIN ERBIN CSDE1 CSDE1 ENSCANP00000022288 ENSCANP00000022288 AKT2 AKT2 PIK3R1 PIK3R1 EREG EREG ENSCANP00000019847 ENSCANP00000019847 ENSCANP00000019829 ENSCANP00000019829 ENSCANP00000019642 ENSCANP00000019642 USP8 USP8 EGF EGF DIAPH1 DIAPH1 LOC105512038 LOC105512038 EGFR EGFR GRB2 GRB2 LOC105509062 LOC105509062 SRC SRC NRG3 NRG3 BTC BTC GAB1 GAB1 FNDC3B FNDC3B YES1 YES1 PTK6 PTK6 PTPN12 PTPN12 GRB7 GRB7 SOS1 SOS1 PRKCE PRKCE LOC105515285 LOC105515285 AKT3 AKT3 NRG1 NRG1 ENSCANP00000024192 ENSCANP00000024192 LOC105527499 LOC105527499 SHC1 SHC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FYNTyrosine-protein kinase. (537 aa)
NRG4Neuregulin 4. (115 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC105503496Ubiquitin-like domain-containing protein. (147 aa)
CUL5Cullin 5; Belongs to the cullin family. (780 aa)
LOC105504658Uncharacterized protein. (571 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
ERBB4Receptor protein-tyrosine kinase. (1283 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa)
LOC105523183Ubiquitin-like domain-containing protein. (77 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
NRG2Neuregulin 2. (671 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (821 aa)
ENSCANP00000008262USP8_dimer domain-containing protein. (105 aa)
ERBB2Receptor protein-tyrosine kinase. (1259 aa)
RHOARas homolog family member A. (193 aa)
ENSCANP00000007912Ubiquitin-like domain-containing protein. (121 aa)
RNF41Ring finger protein 41. (317 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1330 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
MATKTyrosine-protein kinase. (507 aa)
MEMO1Uncharacterized protein. (297 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
ENSCANP00000004759Ubiquitin-like domain-containing protein. (147 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
STUB1STIP1 homology and U-box containing protein 1. (250 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
LOC105517114Ubiquitin-like domain-containing protein. (156 aa)
ERASES cell expressed Ras. (233 aa)
LOC105521899Ubiquitin-like domain-containing protein. (146 aa)
ENSCANP00000000485Ubiquitin-like domain-containing protein. (72 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
CDC37Cell division cycle 37. (378 aa)
ERBINErbb2 interacting protein. (1418 aa)
CSDE1Uncharacterized protein. (844 aa)
ENSCANP00000022288Ubiquitin-like domain-containing protein. (79 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (478 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
EREGEpiregulin. (169 aa)
ENSCANP00000019847Uncharacterized protein. (250 aa)
ENSCANP00000019829Uncharacterized protein. (98 aa)
ENSCANP00000019642Ribosomal_S27 domain-containing protein. (93 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1118 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
DIAPH1Diaphanous related formin 1. (1236 aa)
LOC105512038Uncharacterized protein. (357 aa)
EGFRReceptor protein-tyrosine kinase. (1188 aa)
GRB2Uncharacterized protein. (156 aa)
LOC105509062Uncharacterized protein. (647 aa)
SRCTyrosine-protein kinase. (458 aa)
NRG3Neuregulin 3. (627 aa)
BTCBetacellulin. (178 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
YES1Tyrosine-protein kinase. (548 aa)
PTK6Tyrosine-protein kinase. (451 aa)
PTPN12Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (775 aa)
GRB7Growth factor receptor bound protein 7. (558 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1310 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
LOC105515285HATPase_c domain-containing protein. (711 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
NRG1Neuregulin 1. (645 aa)
ENSCANP00000024192HATPase_c domain-containing protein. (669 aa)
LOC105527499Uncharacterized protein. (381 aa)
SHC1SHC adaptor protein 1. (584 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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