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| | MEF2A | Myocyte enhancer factor 2A. (512 aa) |
| | IRF3 | Interferon regulatory factor 3. (426 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (970 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (403 aa) |
| | SARM1 | Sterile alpha and TIR motif containing 1. (594 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (604 aa) |
| | RPS6KA3 | Ribosomal protein S6 kinase. (742 aa) |
| | NLRP13 | NLR family pyrin domain containing 13. (1021 aa) |
| | ENSCANP00000025746 | Uncharacterized protein; Belongs to the SKP1 family. (167 aa) |
| | ENSCANP00000025796 | Uncharacterized protein. (269 aa) |
| | ENSCANP00000025859 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (140 aa) |
| | MAPKAPK3 | MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1356 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (343 aa) |
| | CTSS | Cathepsin S; Belongs to the peptidase C1 family. (331 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa) |
| | MAPK15 | Mitogen-activated protein kinase. (545 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (275 aa) |
| | TICAM1 | Toll like receptor adaptor molecule 1. (517 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (165 aa) |
| | LOC105525747 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (636 aa) |
| | PPP4R1 | Protein phosphatase 4 regulatory subunit 1. (923 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | DNM2 | Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (840 aa) |
| | CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (396 aa) |
| | S100A8 | Protein S100; Belongs to the S-100 family. (92 aa) |
| | RBSN | Rabenosyn, RAB effector. (785 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (548 aa) |
| | S100B | S_100 domain-containing protein; Belongs to the S-100 family. (94 aa) |
| | CTSL | Cathepsin L; Belongs to the peptidase C1 family. (333 aa) |
| | RIPK3 | Receptor interacting serine/threonine kinase 3. (518 aa) |
| | APP | Amyloid beta precursor protein. (770 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (246 aa) |
| | LRRC45 | Leucine rich repeat containing 45. (670 aa) |
| | FBXW11 | F-box and WD repeat domain containing 11. (542 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa) |
| | DNM1 | Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (774 aa) |
| | LOC105522998 | Uncharacterized protein. (693 aa) |
| | ENSCANP00000031076 | C-type lectin domain-containing protein. (132 aa) |
| | LOC105502444 | C-type lectin domain-containing protein. (248 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (317 aa) |
| | PELI2 | Pellino E3 ubiquitin protein ligase family member 2. (394 aa) |
| | TLR9 | TIR domain-containing protein. (1033 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (438 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (594 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1040 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (275 aa) |
| | ENSCANP00000039105 | Uncharacterized protein. (106 aa) |
| | SIGIRR | Single Ig and TIR domain containing. (410 aa) |
| | KHNYN | KH and NYN domain containing. (678 aa) |
| | ENSCANP00000039354 | Protein kinase domain-containing protein. (353 aa) |
| | RPS6KA5 | Ribosomal protein S6 kinase. (802 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | BPI | Bactericidal permeability increasing protein. (487 aa) |
| | UNC93B1 | Unc-93 homolog B1, TLR signaling regulator. (591 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | LOC105508582 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (122 aa) |
| | LOC105508579 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (130 aa) |
| | RPS6KA2 | Ribosomal protein S6 kinase. (758 aa) |
| | ATF7 | Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (494 aa) |
| | S100A1 | Protein S100; Belongs to the S-100 family. (147 aa) |
| | PPP4R4 | Protein phosphatase 4 regulatory subunit 4. (854 aa) |
| | NLRX1 | NLR family member X1. (972 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (369 aa) |
| | ENSCANP00000036145 | Uncharacterized protein. (268 aa) |
| | FGG | Fibrinogen gamma chain. (453 aa) |
| | HMGB1 | Uncharacterized protein. (206 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (667 aa) |
| | CTSV | Cathepsin V; Belongs to the peptidase C1 family. (334 aa) |
| | FNBP4 | Formin binding protein 4. (950 aa) |
| | VRK3 | VRK serine/threonine kinase 3. (475 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | LOC105525710 | Uncharacterized protein. (3238 aa) |
| | ENSCANP00000034934 | SH2 domain-containing protein. (183 aa) |
| | NLRC5 | NLR family CARD domain containing 5. (1866 aa) |
| | HSP90B1 | Heat shock protein 90 beta family member 1. (804 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa) |
| | MAPKAPK2 | MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (431 aa) |
| | ENSCANP00000033944 | Uncharacterized protein; Belongs to the SKP1 family. (131 aa) |
| | CD36 | CD36 molecule; Belongs to the CD36 family. (472 aa) |
| | ITGAM | Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa) |
| | LOC105504558 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (87 aa) |
| | LRRC71 | Leucine rich repeat containing 71. (559 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) |
| | PELI3 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) |
| | LOC105523183 | Ubiquitin-like domain-containing protein. (77 aa) |
| | ENSCANP00000012071 | Uncharacterized protein. (157 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa) |
| | FOSL2 | FOS like 2, AP-1 transcription factor subunit. (309 aa) |
| | LRRC14 | Leucine rich repeat containing 14. (493 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (538 aa) |
| | UBE2D2 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | USP14 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (490 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (200 aa) |
| | GSDMB | Gasdermin B. (385 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | VWC2 | Von Willebrand factor C domain containing 2. (325 aa) |
| | CNPY3 | Canopy FGF signaling regulator 3. (277 aa) |
| | BTK | Tyrosine-protein kinase. (692 aa) |
| | UBE2NL | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa) |
| | IRF7 | Interferon regulatory factor 7. (503 aa) |
| | TICAM2 | Toll like receptor adaptor molecule 2. (235 aa) |
| | LGMN | Legumain. (433 aa) |
| | CCDC71L | Uncharacterized protein. (307 aa) |
| | BPIFC | BPI fold containing family C. (455 aa) |
| | ENSCANP00000015227 | Uncharacterized protein. (355 aa) |
| | ITGB2 | Integrin beta. (769 aa) |
| | RPS6KA1 | Ribosomal protein S6 kinase. (728 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa) |
| | NKIRAS1 | NFKB inhibitor interacting Ras like 1. (192 aa) |
| | LOC105503496 | Ubiquitin-like domain-containing protein. (147 aa) |
| | MAP3K20 | Mitogen-activated protein kinase kinase kinase 20. (800 aa) |
| | UNC93A | Unc-93 homolog A. (457 aa) |
| | MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) |
| | DUSP4 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa) |
| | RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1250 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa) |
| | LOC105520631 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (140 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | CTSB | Cathepsin B; Belongs to the peptidase C1 family. (339 aa) |
| | NFKB2 | Nuclear factor kappa B subunit 2. (900 aa) |
| | PTPN4 | Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (926 aa) |
| | PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) |
| | TNIP2 | TNFAIP3 interacting protein 2. (322 aa) |
| | ENSCANP00000018891 | Uncharacterized protein; Belongs to the SKP1 family. (137 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (550 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | IRAK2 | Interleukin 1 receptor associated kinase 2. (625 aa) |
| | NLRP6 | NLR family pyrin domain containing 6. (1041 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (648 aa) |
| | MAP3K8 | Mitogen-activated protein kinase kinase kinase 8. (467 aa) |
| | LY96 | Lymphocyte antigen 96. (160 aa) |
| | ENSCANP00000019642 | Ribosomal_S27 domain-containing protein. (93 aa) |
| | LOC105507991 | Uncharacterized protein. (869 aa) |
| | NFKBIB | NFKB inhibitor beta. (321 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | NLRP9 | NLR family pyrin domain containing 9. (876 aa) |
| | UBE2N | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (142 aa) |
| | DUSP3 | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa) |
| | CD180 | CD180 molecule. (661 aa) |
| | FGB | Fibrinogen beta chain. (491 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (373 aa) |
| | ENSCANP00000022288 | Ubiquitin-like domain-containing protein. (79 aa) |
| | NAIP | NLR family apoptosis inhibitory protein. (1369 aa) |
| | LRRC74B | Leucine rich repeat containing 74B. (366 aa) |
| | DUSP6 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa) |
| | APOB | Apolipoprotein B. (4555 aa) |
| | LRRC34 | Leucine rich repeat containing 34. (415 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (156 aa) |
| | LBP | Lipopolysaccharide binding protein. (474 aa) |
| | ENSCANP00000000485 | Ubiquitin-like domain-containing protein. (72 aa) |
| | LOC105513286 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | LOC105521899 | Ubiquitin-like domain-containing protein. (146 aa) |
| | CREM | cAMP responsive element modulator. (322 aa) |
| | TBK1 | TANK binding kinase 1. (713 aa) |
| | LOC105501700 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (306 aa) |
| | CNPY4 | Canopy FGF signaling regulator 4. (245 aa) |
| | S100A9 | Protein S100; Belongs to the S-100 family. (114 aa) |
| | TLR7 | Toll like receptor 7; Belongs to the Toll-like receptor family. (1049 aa) |
| | LRRC74A | Leucine rich repeat containing 74A. (488 aa) |
| | ENSCANP00000001894 | Uncharacterized protein. (215 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (468 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1257 aa) |
| | LOC105517114 | Ubiquitin-like domain-containing protein. (156 aa) |
| | CTSK | Cathepsin K; Belongs to the peptidase C1 family. (329 aa) |
| | ENSCANP00000002557 | Uncharacterized protein. (535 aa) |
| | TLR10 | Toll like receptor 10; Belongs to the Toll-like receptor family. (811 aa) |
| | TIFA | TRAF interacting protein with forkhead associated domain. (185 aa) |
| | LOC105509542 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | PIK3R4 | Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa) |
| | LOC105507704 | ETS domain-containing protein. (403 aa) |
| | LOC105515808 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa) |
| | LRRC31 | Leucine rich repeat containing 31. (552 aa) |
| | TLR1 | Toll-like receptor. (786 aa) |
| | IRAK3 | Interleukin 1 receptor associated kinase 3. (553 aa) |
| | TLR2 | Toll-like receptor. (784 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) |
| | ENSCANP00000004194 | CCHC NOA-type domain-containing protein. (374 aa) |
| | ENSCANP00000004477 | Uncharacterized protein. (192 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | BIRC7 | Baculoviral IAP repeat containing 7. (298 aa) |
| | ENSCANP00000004759 | Ubiquitin-like domain-containing protein. (147 aa) |
| | TONSL | Tonsoku like, DNA repair protein. (1240 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | TIRAP | TIR domain containing adaptor protein. (220 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa) |
| | TANK | TRAF family member associated NFKB activator. (425 aa) |
| | GSDME | Gasdermin E. (496 aa) |
| | FGA | Fibrinogen alpha chain. (909 aa) |
| | DUSP7 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (373 aa) |
| | MEF2C | Myocyte enhancer factor 2C. (483 aa) |
| | ENSCANP00000006830 | Protein kinase domain-containing protein. (373 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | ELK1 | ETS domain-containing protein. (428 aa) |
| | ATF1 | Activating transcription factor 1. (270 aa) |
| | NFKBIA | NFKB inhibitor alpha. (317 aa) |
| | TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa) |
| | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (605 aa) |
| | EEA1 | Early endosome antigen 1. (1411 aa) |
| | ENSCANP00000007912 | Ubiquitin-like domain-containing protein. (121 aa) |
| | N4BP1 | NEDD4 binding protein 1. (829 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (625 aa) |
| | DNM3 | Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa) |
| | LOC105508581 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (121 aa) |
| | SFTPD | Surfactant protein D. (378 aa) |
| | ECSIT | ECSIT signalling integrator. (432 aa) |
| | LOC105510963 | Serine/threonine-protein phosphatase. (291 aa) |
| | TLR8 | Toll like receptor 8; Belongs to the Toll-like receptor family. (1041 aa) |
| | ALPK1 | Alpha kinase 1. (1244 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | UBE2D1 | Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (399 aa) |
| | LY86 | Lymphocyte antigen 86. (162 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (527 aa) |
| | ENSCANP00000011220 | Uncharacterized protein. (277 aa) |
