STRINGSTRING
RHOA RHOA ENSCANP00000008470 ENSCANP00000008470 ENSCANP00000008732 ENSCANP00000008732 TGFB1 TGFB1 PPP1R15A PPP1R15A SKIL SKIL MTMR4 MTMR4 CCNT2 CCNT2 ITGB6 ITGB6 UBE2D1 UBE2D1 LTBP2 LTBP2 COL1A2 COL1A2 XPO1 XPO1 UBA52 UBA52 USP9X USP9X MEIS3 MEIS3 PARD3 PARD3 LOC105523183 LOC105523183 LOC105516286 LOC105516286 PRKCZ PRKCZ ATP1B4 ATP1B4 ENSCANP00000012853 ENSCANP00000012853 PARD3B PARD3B ITGB1 ITGB1 ENSCANP00000013006 ENSCANP00000013006 PPP1CB PPP1CB TGIF1 TGIF1 NEDD8 NEDD8 IRX1 IRX1 USP15 USP15 EP300 EP300 SNW1 SNW1 MAPK3 MAPK3 FKBP1A FKBP1A LOC105503496 LOC105503496 PMEPA1 PMEPA1 ENSCANP00000017238 ENSCANP00000017238 NCOR1 NCOR1 CDK8 CDK8 STRAP STRAP CDK9 CDK9 ENSCANP00000019087 ENSCANP00000019087 ENSCANP00000019233 ENSCANP00000019233 ENSCANP00000019618 ENSCANP00000019618 ENSCANP00000019642 ENSCANP00000019642 TGFB2 TGFB2 ITGB5 ITGB5 NCOR2 NCOR2 ENSCANP00000022288 ENSCANP00000022288 ENSCANP00000022999 ENSCANP00000022999 ITGB3 ITGB3 YBX1 YBX1 PPP1CC PPP1CC NEDD4L NEDD4L LTBP4 LTBP4 E2F4 E2F4 ZFYVE9 ZFYVE9 SMURF2 SMURF2 MAPK1 MAPK1 ENSCANP00000026743 ENSCANP00000026743 STAT1 STAT1 SP1 SP1 CCNK CCNK CGN CGN SMURF1 SMURF1 SMAD4 SMAD4 LDLRAD4 LDLRAD4 FBN1 FBN1 SERPINE1 SERPINE1 TGFBR1 TGFBR1 WWTR1 WWTR1 MYC MYC HDAC1 HDAC1 UBE2M UBE2M SKI SKI TGFB3 TGFB3 F11R F11R TRIM33 TRIM33 LTBP1 LTBP1 PARP1 PARP1 TFDP2 TFDP2 LTBP3 LTBP3 SMAD2 SMAD2 CDKN2B CDKN2B CCNT1 CCNT1 TFDP1 TFDP1 CBL CBL ITGA8 ITGA8 RBL1 RBL1 RNF111 RNF111 PPM1A PPM1A SMAD3 SMAD3 JUNB JUNB BAMBI BAMBI CCNQ CCNQ TGIF2 TGIF2 MKX MKX MEN1 MEN1 ITGAV ITGAV PPP1CA PPP1CA LOC105517114 LOC105517114 STUB1 STUB1 ENSCANP00000003071 ENSCANP00000003071 LOC105527037 LOC105527037 PARD6A PARD6A PCSK4 PCSK4 ENSCANP00000003939 ENSCANP00000003939 E2F5 E2F5 TGFBR2 TGFBR2 IRX5 IRX5 ENSCANP00000004759 ENSCANP00000004759 ENSCANP00000005988 ENSCANP00000005988 CCNC CCNC FURIN FURIN SMAD7 SMAD7 IRX3 IRX3 ENSCANP00000007443 ENSCANP00000007443 ENSCANP00000007912 ENSCANP00000007912 LOC105521899 LOC105521899 ENSCANP00000000485 ENSCANP00000000485 RPS27A RPS27A ITGB8 ITGB8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RHOARas homolog family member A. (193 aa)
ENSCANP00000008470Uncharacterized protein. (1103 aa)
ENSCANP00000008732CSP domain-containing protein. (296 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (336 aa)
PPP1R15AProtein phosphatase 1 regulatory subunit 15A. (676 aa)
SKILSKI like proto-oncogene. (684 aa)
MTMR4Myotubularin related protein 4. (1195 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (716 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (746 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1821 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
XPO1Exportin 1. (1032 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
USP9XUbiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2418 aa)
MEIS3Meis homeobox 3. (464 aa)
PARD3Par-3 family cell polarity regulator. (1316 aa)
LOC105523183Ubiquitin-like domain-containing protein. (77 aa)
LOC105516286Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (449 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (392 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (357 aa)
ENSCANP00000012853C2 domain-containing protein. (51 aa)
PARD3BPar-3 family cell polarity regulator beta. (1204 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
ENSCANP00000013006Uncharacterized protein. (122 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (322 aa)
TGIF1TGFB induced factor homeobox 1. (392 aa)
NEDD8NEDD8 ubiquitin like modifier. (82 aa)
IRX1Iroquois homeobox 1. (460 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
EP300E1A binding protein p300. (2409 aa)
SNW1SNW domain containing 1. (571 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
FKBP1APeptidylprolyl isomerase. (127 aa)
LOC105503496Ubiquitin-like domain-containing protein. (147 aa)
PMEPA1Prostate transmembrane protein, androgen induced 1. (259 aa)
ENSCANP00000017238CSD_1 domain-containing protein. (323 aa)
NCOR1Nuclear receptor corepressor 1. (2440 aa)
CDK8Cyclin dependent kinase 8; Belongs to the protein kinase superfamily. (464 aa)
STRAPSerine/threonine kinase receptor associated protein. (363 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
ENSCANP00000019087Uncharacterized protein. (298 aa)
ENSCANP00000019233Uncharacterized protein. (380 aa)
ENSCANP00000019618CYCLIN domain-containing protein; Belongs to the cyclin family. (295 aa)
ENSCANP00000019642Ribosomal_S27 domain-containing protein. (93 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (792 aa)
NCOR2Nuclear receptor corepressor 2. (2510 aa)
ENSCANP00000022288Ubiquitin-like domain-containing protein. (79 aa)
ENSCANP00000022999Homeobox domain-containing protein. (276 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
YBX1CSD_1 domain-containing protein. (275 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (1131 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1599 aa)
E2F4E2F transcription factor 4. (370 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1409 aa)
SMURF2E3 ubiquitin-protein ligase. (734 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
ENSCANP00000026743Transcription factor. (322 aa)
STAT1Signal transducer and activator of transcription. (765 aa)
SP1Sp1 transcription factor. (718 aa)
CCNKCyclin K; Belongs to the cyclin family. (515 aa)
CGNMyosin_tail_1 domain-containing protein. (1204 aa)
SMURF1E3 ubiquitin-protein ligase. (763 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
LDLRAD4Low density lipoprotein receptor class A domain containing 4. (306 aa)
FBN1Fibrillin 1. (2816 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (337 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (476 aa)
UBE2MUbiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
SKISKI proto-oncogene. (649 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
F11RF11 receptor. (322 aa)
TRIM33Tripartite motif containing 33. (1046 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1510 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
TFDP2Transcription factor. (446 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1127 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (138 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (728 aa)
TFDP1Transcription factor. (410 aa)
CBLCbl proto-oncogene. (888 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1052 aa)
RBL1RB transcriptional corepressor like 1. (959 aa)
RNF111Ring finger protein 111. (994 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
CCNQCYCLIN domain-containing protein; Belongs to the cyclin family. (226 aa)
TGIF2TGFB induced factor homeobox 2. (237 aa)
MKXMohawk homeobox. (352 aa)
MEN1Menin 1. (610 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (329 aa)
LOC105517114Ubiquitin-like domain-containing protein. (156 aa)
STUB1STIP1 homology and U-box containing protein 1. (250 aa)
ENSCANP00000003071SER_THR_PHOSPHATASE domain-containing protein. (146 aa)
LOC105527037Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (459 aa)
PARD6APar-6 family cell polarity regulator alpha. (345 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (707 aa)
ENSCANP00000003939PPM-type phosphatase domain-containing protein. (346 aa)
E2F5E2F transcription factor 5. (343 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
IRX5Iroquois homeobox 5. (483 aa)
ENSCANP00000004759Ubiquitin-like domain-containing protein. (147 aa)
ENSCANP00000005988Peptidylprolyl isomerase. (107 aa)
CCNCCyclin C; Belongs to the cyclin family. (283 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa)
SMAD7Mothers against decapentaplegic homolog. (431 aa)
IRX3Iroquois homeobox 3. (411 aa)
ENSCANP00000007443Peptidylprolyl isomerase. (127 aa)
ENSCANP00000007912Ubiquitin-like domain-containing protein. (121 aa)
LOC105521899Ubiquitin-like domain-containing protein. (146 aa)
ENSCANP00000000485Ubiquitin-like domain-containing protein. (72 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (769 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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