STRINGSTRING
ANGPTL8 ANGPTL8 LOC105517114 LOC105517114 VLDLR VLDLR ANGPTL3 ANGPTL3 PCSK4 PCSK4 NR1H3 NR1H3 SAR1B SAR1B LMF1 LMF1 CLHC1 CLHC1 ENSCANP00000004759 ENSCANP00000004759 PLG PLG FGF21 FGF21 APOA4 APOA4 FURIN FURIN APOC3 APOC3 APOA5 APOA5 PRKACB PRKACB AMN AMN PTCHD1 PTCHD1 ENSCANP00000007912 ENSCANP00000007912 LDLR LDLR PTCHD3 PTCHD3 AP2M1 AP2M1 LMF2 LMF2 GPIHBP1 GPIHBP1 LOC105524083 LOC105524083 LIPC LIPC APOC4 APOC4 APOA2 APOA2 UBA52 UBA52 LOC105523183 LOC105523183 SOAT2 SOAT2 LOC105519768 LOC105519768 APOF APOF PLEKHD1 PLEKHD1 ABCA1 ABCA1 LIPA LIPA PCSK6 PCSK6 LPL LPL CETP CETP MBTPS1 MBTPS1 PDIA2 PDIA2 LSR LSR PRKACA PRKACA ZDHHC19 ZDHHC19 ALB ALB APOE APOE ENSCANP00000019642 ENSCANP00000019642 MBTPS2 MBTPS2 MYLIP MYLIP ZDHHC8 ZDHHC8 HDLBP HDLBP CIDEC CIDEC ILDR2 ILDR2 AP2S1 AP2S1 NPC2 NPC2 PTCHD4 PTCHD4 LIPG LIPG ENSCANP00000022288 ENSCANP00000022288 A2ML1 A2ML1 NR1H2 NR1H2 CUBN CUBN PZP PZP ABCG1 ABCG1 AP2B1 AP2B1 LOC105501272 LOC105501272 AADACL3 AADACL3 CLTC CLTC P4HB P4HB ENSCANP00000029966 ENSCANP00000029966 CDCP2 CDCP2 SOAT1 SOAT1 SAR1A SAR1A PCSK5 PCSK5 SCARB1 SCARB1 AP2A2 AP2A2 ENSCANP00000034239 ENSCANP00000034239 LOC105525710 LOC105525710 CLTA CLTA NCEH1 NCEH1 NPC1 NPC1 LDLRAP1 LDLRAP1 PCSK9 PCSK9 AADACL4 AADACL4 CREB3L3 CREB3L3 AP2A1 AP2A1 A2M A2M BMP1 BMP1 APOA1 APOA1 PLTP PLTP LCAT LCAT MTTP MTTP SMPDL3A SMPDL3A LOC105503496 LOC105503496 APOC2 APOC2 APOB APOB RPS27A RPS27A ENSCANP00000000485 ENSCANP00000000485 LOC105521899 LOC105521899 APOBR APOBR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANGPTL8Angiopoietin like 8. (198 aa)
LOC105517114Ubiquitin-like domain-containing protein. (156 aa)
VLDLRVery low density lipoprotein receptor. (873 aa)
ANGPTL3Angiopoietin like 3. (460 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (707 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (453 aa)
SAR1BSecretion associated Ras related GTPase 1B. (163 aa)
LMF1Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (567 aa)
CLHC1Clathrin heavy chain linker domain-containing protein 1. (464 aa)
ENSCANP00000004759Ubiquitin-like domain-containing protein. (147 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (810 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
APOA4Apolipoprotein A4. (412 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa)
APOC3Apolipoprotein C3. (117 aa)
APOA5Apolipoprotein A5. (366 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
AMNAmnion associated transmembrane protein. (453 aa)
PTCHD1Patched domain containing 1. (888 aa)
ENSCANP00000007912Ubiquitin-like domain-containing protein. (121 aa)
LDLRLow density lipoprotein receptor. (777 aa)
PTCHD3Patched domain containing 3. (760 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (458 aa)
LMF2Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (707 aa)
GPIHBP1Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. (141 aa)
LOC105524083CIDE-N domain-containing protein. (126 aa)
LIPCLipase C, hepatic type. (499 aa)
APOC4Uncharacterized protein. (127 aa)
APOA2Apolipoprotein A2. (100 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
LOC105523183Ubiquitin-like domain-containing protein. (77 aa)
SOAT2O-acyltransferase. (460 aa)
LOC105519768Uncharacterized protein. (1218 aa)
APOFApolipoprotein F. (326 aa)
PLEKHD1Pleckstrin homology and coiled-coil domain containing D1. (506 aa)
ABCA1ATP binding cassette subfamily A member 1. (2264 aa)
LIPALipase; Belongs to the AB hydrolase superfamily. Lipase family. (399 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (928 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
CETPCholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (493 aa)
MBTPS1Membrane bound transcription factor peptidase, site 1. (1052 aa)
PDIA2Protein disulfide isomerase family A member 2. (525 aa)
LSRLipolysis stimulated lipoprotein receptor. (754 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (345 aa)
ZDHHC19Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (307 aa)
ALBAlbumin. (604 aa)
APOEApolipoprotein E. (189 aa)
ENSCANP00000019642Ribosomal_S27 domain-containing protein. (93 aa)
MBTPS2Membrane bound transcription factor peptidase, site 2. (520 aa)
MYLIPMyosin regulatory light chain interacting protein. (445 aa)
ZDHHC8Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (760 aa)
HDLBPHigh density lipoprotein binding protein. (1269 aa)
CIDECCIDE-N domain-containing protein. (133 aa)
ILDR2Immunoglobulin like domain containing receptor 2. (565 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
NPC2NPC intracellular cholesterol transporter 2. (229 aa)
PTCHD4Patched domain containing 4. (846 aa)
LIPGLipase G, endothelial type. (500 aa)
ENSCANP00000022288Ubiquitin-like domain-containing protein. (79 aa)
A2ML1Alpha-2-macroglobulin like 1. (1454 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (459 aa)
CUBNCubilin. (3601 aa)
PZPPZP alpha-2-macroglobulin like. (1482 aa)
ABCG1ATP binding cassette subfamily G member 1. (684 aa)
AP2B1AP complex subunit beta. (951 aa)
LOC105501272Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (222 aa)
AADACL3Arylacetamide deacetylase like 3. (407 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
P4HBProtein disulfide-isomerase. (506 aa)
ENSCANP00000029966B2-adapt-app_C domain-containing protein. (214 aa)
CDCP2CUB domain containing protein 2. (540 aa)
SOAT1O-acyltransferase. (525 aa)
SAR1AUncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1758 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (950 aa)
ENSCANP00000034239Uncharacterized protein. (1410 aa)
LOC105525710Uncharacterized protein. (3238 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (237 aa)
NCEH1Neutral cholesterol ester hydrolase 1. (448 aa)
NPC1NPC intracellular cholesterol transporter 1. (1277 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (278 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (692 aa)
AADACL4Arylacetamide deacetylase like 4. (407 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (415 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (953 aa)
A2MAlpha-2-macroglobulin. (1474 aa)
BMP1Metalloendopeptidase. (980 aa)
APOA1Apolipoprotein A1. (267 aa)
PLTPPhospholipid transfer protein. (493 aa)
LCATLecithin-cholesterol acyltransferase. (440 aa)
MTTPMicrosomal triglyceride transfer protein. (909 aa)
SMPDL3AAcid sphingomyelinase-like phosphodiesterase. (453 aa)
LOC105503496Ubiquitin-like domain-containing protein. (147 aa)
APOC2Apolipoprotein C2. (101 aa)
APOBApolipoprotein B. (4555 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSCANP00000000485Ubiquitin-like domain-containing protein. (72 aa)
LOC105521899Ubiquitin-like domain-containing protein. (146 aa)
APOBRApolipoprotein B receptor. (1063 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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