STRINGSTRING
ENSCANP00000007912 ENSCANP00000007912 ARHGEF7 ARHGEF7 EPS15L1 EPS15L1 ADAM17 ADAM17 PXN PXN PTPRT PTPRT PAG1 PAG1 CSK CSK ENSCANP00000011118 ENSCANP00000011118 ENSCANP00000011220 ENSCANP00000011220 UBA52 UBA52 LOC105523183 LOC105523183 PLCG1 PLCG1 SH3GL3 SH3GL3 ENSCANP00000013076 ENSCANP00000013076 AAMP AAMP STAM2 STAM2 ENSCANP00000014881 ENSCANP00000014881 LOC105504658 LOC105504658 LRIG3 LRIG3 LOC105503496 LOC105503496 PIK3CA PIK3CA STAM STAM EGFR EGFR EGF EGF ENSCANP00000019642 ENSCANP00000019642 ENSCANP00000019829 ENSCANP00000019829 EREG EREG PTPN3 PTPN3 PIK3R1 PIK3R1 LOC105524044 LOC105524044 ENSCANP00000022288 ENSCANP00000022288 CSDE1 CSDE1 SHC1 SHC1 SH3GL2 SH3GL2 LRIG2 LRIG2 ENSCANP00000025796 ENSCANP00000025796 TGFB1I1 TGFB1I1 SH3GL1 SH3GL1 SPRY2 SPRY2 RNF222 RNF222 ADAM10 ADAM10 ENSCANP00000032593 ENSCANP00000032593 SOS1 SOS1 PTPN11 PTPN11 ENSCANP00000033455 ENSCANP00000033455 HGS HGS ENSCANP00000034934 ENSCANP00000034934 PTPN12 PTPN12 LRIG1 LRIG1 FNDC3B FNDC3B ENSCANP00000036145 ENSCANP00000036145 PTPRK PTPRK EPS15 EPS15 EPN1 EPN1 GAB1 GAB1 EPGN EPGN LPXN LPXN BTC BTC CDC42 CDC42 ADAM12 ADAM12 AREG AREG CBL CBL SRC SRC GRB2 GRB2 RPS27A RPS27A ENSCANP00000000485 ENSCANP00000000485 LOC105521899 LOC105521899 ERAS ERAS SPRY1 SPRY1 LOC105517114 LOC105517114 ENSCANP00000002557 ENSCANP00000002557 FNDC3A FNDC3A ENSCANP00000004759 ENSCANP00000004759 ENSCANP00000005072 ENSCANP00000005072 HRAS HRAS SH3KBP1 SH3KBP1 HBEGF HBEGF TGFA TGFA KRAS KRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCANP00000007912Ubiquitin-like domain-containing protein. (121 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (748 aa)
EPS15L1Epidermal growth factor receptor pathway substrate 15 like 1. (857 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
PXNPaxillin. (1076 aa)
PTPRTProtein tyrosine phosphatase receptor type T. (1421 aa)
PAG1Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (432 aa)
CSKTyrosine-protein kinase. (450 aa)
ENSCANP00000011118Uncharacterized protein. (176 aa)
ENSCANP00000011220Uncharacterized protein. (277 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
LOC105523183Ubiquitin-like domain-containing protein. (77 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (354 aa)
ENSCANP00000013076Uncharacterized protein. (164 aa)
AAMPAngio associated migratory cell protein. (462 aa)
STAM2Signal transducing adaptor molecule 2. (525 aa)
ENSCANP00000014881Uncharacterized protein. (279 aa)
LOC105504658Uncharacterized protein. (571 aa)
LRIG3Leucine rich repeats and immunoglobulin like domains 3. (1070 aa)
LOC105503496Ubiquitin-like domain-containing protein. (147 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
STAMSignal transducing adaptor molecule. (540 aa)
EGFRReceptor protein-tyrosine kinase. (1188 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
ENSCANP00000019642Ribosomal_S27 domain-containing protein. (93 aa)
ENSCANP00000019829Uncharacterized protein. (98 aa)
EREGEpiregulin. (169 aa)
PTPN3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (913 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
LOC105524044Uncharacterized protein. (999 aa)
ENSCANP00000022288Ubiquitin-like domain-containing protein. (79 aa)
CSDE1Uncharacterized protein. (844 aa)
SHC1SHC adaptor protein 1. (584 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (337 aa)
LRIG2Leucine rich repeats and immunoglobulin like domains 2. (1065 aa)
ENSCANP00000025796Uncharacterized protein. (269 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa)
SH3GL1SH3 domain containing GRB2 like 1, endophilin A2. (365 aa)
SPRY2Sprouty RTK signaling antagonist 2. (315 aa)
RNF222Ring finger protein 222. (220 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
ENSCANP00000032593EH domain-containing protein. (109 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1310 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa)
ENSCANP00000033455BAR domain-containing protein. (299 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
ENSCANP00000034934SH2 domain-containing protein. (183 aa)
PTPN12Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (775 aa)
LRIG1Uncharacterized protein. (1039 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
ENSCANP00000036145Uncharacterized protein. (268 aa)
PTPRKProtein tyrosine phosphatase receptor type K. (1421 aa)
EPS15Epidermal growth factor receptor pathway substrate 15. (886 aa)
EPN1Epsin 1. (662 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
EPGNEpithelial mitogen. (154 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa)
BTCBetacellulin. (178 aa)
CDC42Cell division cycle 42. (191 aa)
ADAM12ADAM metallopeptidase domain 12. (879 aa)
AREGAmphiregulin. (275 aa)
CBLCbl proto-oncogene. (888 aa)
SRCTyrosine-protein kinase. (458 aa)
GRB2Uncharacterized protein. (156 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSCANP00000000485Ubiquitin-like domain-containing protein. (72 aa)
LOC105521899Ubiquitin-like domain-containing protein. (146 aa)
ERASES cell expressed Ras. (233 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
LOC105517114Ubiquitin-like domain-containing protein. (156 aa)
ENSCANP00000002557Uncharacterized protein. (535 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
ENSCANP00000004759Ubiquitin-like domain-containing protein. (147 aa)
ENSCANP00000005072Uncharacterized protein. (168 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
SH3KBP1SH3 domain containing kinase binding protein 1. (663 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
TGFATransforming growth factor alpha. (166 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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