STRINGSTRING
NEDD9 NEDD9 CASS4 CASS4 ACTL7B ACTL7B ACTL7A ACTL7A ERAS ERAS MAPK11 MAPK11 ITGAV ITGAV CYFIP2 CYFIP2 PRKCA PRKCA FNDC3A FNDC3A ENSCANP00000004265 ENSCANP00000004265 PRKCD PRKCD BAIAP2 BAIAP2 ENSCANP00000005072 ENSCANP00000005072 HRAS HRAS PAK1 PAK1 KRAS KRAS PRKACB PRKACB RHOA RHOA HSP90AA1 HSP90AA1 NCF2 NCF2 VAV2 VAV2 ENSCANP00000008647 ENSCANP00000008647 CAV1 CAV1 CYBB CYBB PXN PXN ENSCANP00000011118 ENSCANP00000011118 PTK2B PTK2B TENM4 TENM4 CTNNB1 CTNNB1 VEGFC VEGFC PRKCZ PRKCZ PLCG1 PLCG1 NCK2 NCK2 TENM3 TENM3 TENM2 TENM2 ENSCANP00000013074 ENSCANP00000013074 ENSCANP00000013076 ENSCANP00000013076 STX12 STX12 MAPK12 MAPK12 SHD SHD AAMP AAMP AKT1 AKT1 NOS3 NOS3 ELMO1 ELMO1 LOC105504658 LOC105504658 RASA1 RASA1 ROCK1 ROCK1 ELMO3 ELMO3 NCKAP1 NCKAP1 VAV1 VAV1 TRIB3 TRIB3 FLT4 FLT4 PIK3CA PIK3CA DOCK1 DOCK1 ENSCANP00000016772 ENSCANP00000016772 CRK CRK NCKAP1L NCKAP1L ENSCANP00000017605 ENSCANP00000017605 SZRD1 SZRD1 FYN FYN PRKACA PRKACA RICTOR RICTOR ENSCANP00000018854 ENSCANP00000018854 ENSCANP00000019829 ENSCANP00000019829 LOC105524240 LOC105524240 EFS EFS WASF1 WASF1 SHE SHE WASF2 WASF2 LOC105514986 LOC105514986 CYFIP1 CYFIP1 CDH5 CDH5 PIK3R1 PIK3R1 AKT2 AKT2 MTOR MTOR BCAR1 BCAR1 PRKCB PRKCB ARVCF ARVCF MLST8 MLST8 ITPR3 ITPR3 PDPK1 PDPK1 CSDE1 CSDE1 CYBA CYBA SPHK1 SPHK1 ITGB3 ITGB3 ENSCANP00000024192 ENSCANP00000024192 TENM1 TENM1 ABI1 ABI1 LOC105527362 LOC105527362 SHC2 SHC2 ACTL8 ACTL8 SH2D2A SH2D2A VEGFD VEGFD PAK3 PAK3 PGF PGF LOC105521231 LOC105521231 MAPKAPK3 MAPKAPK3 TGFB1I1 TGFB1I1 BRK1 BRK1 THEM4 THEM4 AXL AXL AKT3 AKT3 ABI2 ABI2 LOC105512042 LOC105512042 SHB SHB VEGFA VEGFA ITPR1 ITPR1 FLT1 FLT1 LOC105515285 LOC105515285 RNF222 RNF222 PIK3CB PIK3CB AHCYL1 AHCYL1 PAK2 PAK2 STX7 STX7 ROCK2 ROCK2 PIK3R2 PIK3R2 CTNND1 CTNND1 NCF1 NCF1 NCK1 NCK1 KDR KDR NCF4 NCF4 NRP2 NRP2 MAPK13 MAPK13 ACTG1 ACTG1 MAPKAPK2 MAPKAPK2 CTNNA1 CTNNA1 NRP1 NRP1 SHF SHF FNDC3B FNDC3B ENSCANP00000036167 ENSCANP00000036167 VEGFB VEGFB PTK2 PTK2 LPXN LPXN ITPR2 ITPR2 CDC42 CDC42 VAV3 VAV3 MAPKAP1 MAPKAP1 POTEE POTEE WASF3 WASF3 HSH2D HSH2D ELMO2 ELMO2 MAPK14 MAPK14 JUP JUP SRC SRC LOC105509062 LOC105509062
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (839 aa)
CASS4Cas scaffold protein family member 4. (786 aa)
ACTL7BActin like 7B; Belongs to the actin family. (415 aa)
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)
ERASES cell expressed Ras. (233 aa)
MAPK11Mitogen-activated protein kinase. (306 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
ENSCANP00000004265Uncharacterized protein. (37 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
BAIAP2BAI1 associated protein 2. (534 aa)
ENSCANP00000005072Uncharacterized protein. (168 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PAK1Non-specific serine/threonine protein kinase. (555 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
RHOARas homolog family member A. (193 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (821 aa)
NCF2Neutrophil cytosolic factor 2. (498 aa)
VAV2Vav guanine nucleotide exchange factor 2. (810 aa)
ENSCANP00000008647Uncharacterized protein; Belongs to the actin family. (146 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (179 aa)
CYBBCytochrome b-245 beta chain. (570 aa)
PXNPaxillin. (1076 aa)
ENSCANP00000011118Uncharacterized protein. (176 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
TENM4Teneurin transmembrane protein 4. (2769 aa)
CTNNB1Catenin beta 1. (781 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (459 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (392 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa)
NCK2Cytoplasmic protein. (380 aa)
TENM3Teneurin transmembrane protein 3. (2699 aa)
TENM2Teneurin transmembrane protein 2. (2774 aa)
ENSCANP00000013074Uncharacterized protein; Belongs to the actin family. (156 aa)
ENSCANP00000013076Uncharacterized protein. (164 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (276 aa)
MAPK12Mitogen-activated protein kinase. (325 aa)
SHDSrc homology 2 domain containing transforming protein D. (279 aa)
AAMPAngio associated migratory cell protein. (462 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
LOC105504658Uncharacterized protein. (571 aa)
RASA1RAS p21 protein activator 1. (1047 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
ELMO3Engulfment and cell motility 3. (775 aa)
NCKAP1NCK associated protein 1. (1111 aa)
VAV1Vav guanine nucleotide exchange factor 1. (740 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1342 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1870 aa)
ENSCANP00000016772Uncharacterized protein. (67 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
ENSCANP00000017605Uncharacterized protein; Belongs to the actin family. (163 aa)
SZRD1SUZ RNA binding domain containing 1. (152 aa)
FYNTyrosine-protein kinase. (537 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (345 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1698 aa)
ENSCANP00000018854Uncharacterized protein; Belongs to the actin family. (349 aa)
ENSCANP00000019829Uncharacterized protein. (98 aa)
LOC105524240Uncharacterized protein. (370 aa)
EFSEmbryonal Fyn-associated substrate. (561 aa)
WASF1WASP family member 1. (559 aa)
SHESrc homology 2 domain containing E. (411 aa)
WASF2WASP family member 2. (498 aa)
LOC105514986SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (182 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1234 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (717 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (478 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (915 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
ARVCFARVCF delta catenin family member. (962 aa)
MLST8MTOR associated protein, LST8 homolog. (335 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (406 aa)
CSDE1Uncharacterized protein. (844 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (194 aa)
SPHK1Sphingosine kinase 1. (448 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
ENSCANP00000024192HATPase_c domain-containing protein. (669 aa)
TENM1Teneurin transmembrane protein 1. (2732 aa)
ABI1Abl interactor 1. (508 aa)
LOC105527362Uncharacterized protein. (835 aa)
SHC2SHC adaptor protein 2. (381 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
SH2D2ASH2 domain containing 2A. (399 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (200 aa)
LOC105521231Uncharacterized protein; Belongs to the actin family. (376 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
THEM4Thioesterase superfamily member 4. (240 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ABI2Abl interactor 2. (507 aa)
LOC105512042ANK_REP_REGION domain-containing protein; Belongs to the actin family. (796 aa)
SHBSH2 domain containing adaptor protein B. (301 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (412 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2697 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1255 aa)
LOC105515285HATPase_c domain-containing protein. (711 aa)
RNF222Ring finger protein 222. (220 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
STX7Syntaxin 7; Belongs to the syntaxin family. (261 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1383 aa)
PIK3R2Uncharacterized protein. (601 aa)
CTNND1Catenin delta 1. (968 aa)
NCF1Neutrophil cytosolic factor 1. (390 aa)
NCK1Cytoplasmic protein. (377 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
NCF4Neutrophil cytosolic factor 4. (339 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (930 aa)
MAPK13Mitogen-activated protein kinase. (491 aa)
ACTG1Uncharacterized protein. (376 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (431 aa)
CTNNA1Catenin alpha 1. (906 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
SHFSrc homology 2 domain containing F. (415 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
ENSCANP00000036167Uncharacterized protein. (105 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (197 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
CDC42Cell division cycle 42. (191 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
MAPKAP1MAPK associated protein 1. (522 aa)
POTEEANK_REP_REGION domain-containing protein; Belongs to the actin family. (952 aa)
WASF3WASP family member 3. (502 aa)
HSH2DHematopoietic SH2 domain containing. (352 aa)
ELMO2Engulfment and cell motility 2. (726 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
JUPJunction plakoglobin. (746 aa)
SRCTyrosine-protein kinase. (458 aa)
LOC105509062Uncharacterized protein. (647 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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