STRINGSTRING
RRAD RRAD ID1 ID1 PPP4R4 PPP4R4 PPP2R1B PPP2R1B FOSB FOSB TCF12 TCF12 VRK3 VRK3 EGR1 EGR1 REST REST MAPKAPK2 MAPKAPK2 FOSL1 FOSL1 EGR4 EGR4 EGR2 EGR2 ID2 ID2 ENSCANP00000030238 ENSCANP00000030238 PPP2R1A PPP2R1A PPP2CA PPP2CA DNM2 DNM2 PPP4R1 PPP4R1 PPP2CB PPP2CB SGK1 SGK1 MAPK15 MAPK15 MAPK1 MAPK1 SRF SRF ASCL1 ASCL1 CHD4 CHD4 RPS6KA3 RPS6KA3 MEF2D MEF2D LYL1 LYL1 MEF2A MEF2A DUSP3 DUSP3 TRIB2 TRIB2 MAPK7 MAPK7 DUSP7 DUSP7 MEF2C MEF2C ELK1 ELK1 ATF1 ATF1 PPP2R5D PPP2R5D LOC105510963 LOC105510963 SH3GL3 SH3GL3 TPH1 TPH1 CREB1 CREB1 EP300 EP300 RPS6KA1 RPS6KA1 MAPK3 MAPK3 EGR3 EGR3 DUSP4 DUSP4 RELCH RELCH ID3 ID3 FOS FOS TRIB1 TRIB1 NAB2 NAB2 DUSP6 DUSP6 CREM CREM JUNB JUNB F3 F3 MAPK11 MAPK11 NAB1 NAB1 LOC105507704 LOC105507704 CDK5R1 CDK5R1 ARC ARC ATF2 ATF2 FNBP4 FNBP4 RPS6KA5 RPS6KA5 MAPK14 MAPK14 LOC105507991 LOC105507991 CDK5 CDK5 ENSCANP00000020706 ENSCANP00000020706 RPS6KA2 RPS6KA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (154 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (854 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (667 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
TCF12Transcription factor 12. (706 aa)
VRK3VRK serine/threonine kinase 3. (475 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (527 aa)
RESTRE1 silencing transcription factor. (1096 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (431 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
EGR4Early growth response 4. (589 aa)
EGR2Early growth response 2. (476 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
ENSCANP00000030238Uncharacterized protein. (315 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (594 aa)
PPP2CASerine/threonine-protein phosphatase. (275 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (840 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (923 aa)
PPP2CBSerine/threonine-protein phosphatase. (275 aa)
SGK1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (500 aa)
MAPK15Mitogen-activated protein kinase. (545 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
SRFSerum response factor. (406 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (231 aa)
CHD4Uncharacterized protein. (1882 aa)
RPS6KA3Ribosomal protein S6 kinase. (742 aa)
MEF2DMyocyte enhancer factor 2D. (521 aa)
LYL1LYL1 basic helix-loop-helix family member. (280 aa)
MEF2AMyocyte enhancer factor 2A. (512 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
TRIB2Tribbles pseudokinase 2. (343 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (373 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
ELK1ETS domain-containing protein. (428 aa)
ATF1Activating transcription factor 1. (270 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (605 aa)
LOC105510963Serine/threonine-protein phosphatase. (291 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (354 aa)
TPH1Tryptophan hydroxylase 1. (444 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
EP300E1A binding protein p300. (2409 aa)
RPS6KA1Ribosomal protein S6 kinase. (728 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
EGR3Early growth response 3. (387 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1250 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
TRIB1Tribbles pseudokinase 1. (206 aa)
NAB2NGFI-A binding protein 2. (525 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
CREMcAMP responsive element modulator. (322 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
F3Coagulation factor III, tissue factor. (296 aa)
MAPK11Mitogen-activated protein kinase. (306 aa)
NAB1NGFI-A binding protein 1. (487 aa)
LOC105507704ETS domain-containing protein. (403 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
ARCActivity regulated cytoskeleton associated protein. (396 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
FNBP4Formin binding protein 4. (950 aa)
RPS6KA5Ribosomal protein S6 kinase. (802 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
LOC105507991Uncharacterized protein. (869 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (302 aa)
ENSCANP00000020706Protein kinase domain-containing protein. (281 aa)
RPS6KA2Ribosomal protein S6 kinase. (758 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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