STRINGSTRING
SMURF2 SMURF2 ZFYVE16 ZFYVE16 NOG NOG GREM2 GREM2 ACVR2A ACVR2A SMAD7 SMAD7 BMPR1B BMPR1B SMAD9 SMAD9 UBE2D1 UBE2D1 CHRDL1 CHRDL1 ACVRL1 ACVRL1 ENSCANP00000012853 ENSCANP00000012853 ACVR1 ACVR1 BMP2 BMP2 BMPR1A BMPR1A GDF2 GDF2 SMAD5 SMAD5 SMAD1 SMAD1 FSTL1 FSTL1 AMHR2 AMHR2 CHRDL2 CHRDL2 CER1 CER1 ACVR2B ACVR2B SMURF1 SMURF1 BMP10 BMP10 SMAD4 SMAD4 SKI SKI BMPR2 BMPR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMURF2E3 ubiquitin-protein ligase. (734 aa)
ZFYVE16Zinc finger FYVE domain-containing protein. (1537 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
GREM2Gremlin. (168 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
SMAD7Mothers against decapentaplegic homolog. (431 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SMAD9Mothers against decapentaplegic homolog. (467 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
CHRDL1Chordin like 1. (458 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
ENSCANP00000012853C2 domain-containing protein. (51 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
GDF2Growth differentiation factor 2. (429 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
FSTL1Follistatin like 1. (317 aa)
AMHR2Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. (573 aa)
CHRDL2Chordin like 2. (452 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (750 aa)
SMURF1E3 ubiquitin-protein ligase. (763 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
SKISKI proto-oncogene. (649 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1030 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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